| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Crizotinib (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Crizotinib (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT18 | keratin 18, type I | 0.196253 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.140373 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.137853 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.13518 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124881 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.100834 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0937427 |
| PLEC | plectin | 0.0857653 |
| DSPP | dentin sialophosphoprotein | 0.0813847 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0803429 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0755471 |
| ACTN4 | actinin, alpha 4 | 0.0751518 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0740967 |
| VIM | vimentin | 0.0717593 |
| PGK1 | phosphoglycerate kinase 1 | 0.0708175 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0694167 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.064452 |
| FLNA | filamin A, alpha | 0.0643124 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0630466 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0627957 |
| CANX | calnexin | 0.0625388 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0582937 |
| RPS4X | ribosomal protein S4, X-linked | 0.057605 |
| BCL2L1 | BCL2-like 1 | 0.0557534 |
| SEPTIN9 | septin 9 | 0.0546161 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0540102 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0512401 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0504055 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.050325 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0490302 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0486576 |
| LMO7 | LIM domain 7 | 0.0475445 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0445558 |
| SMAD3 | SMAD family member 3 | 0.0437833 |
| RPL7 | ribosomal protein L7 | 0.0425886 |
| LDHA | lactate dehydrogenase A | 0.0412515 |
| MKI67 | marker of proliferation Ki-67 | 0.0409958 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0400725 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0381777 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0379784 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0362733 |
| SNX9 | sorting nexin 9 | 0.0349635 |
| MSN | moesin | 0.0349272 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0348806 |
| RPL4 | ribosomal protein L4 | 0.0344296 |
| YME1L1 | YME1-like 1 ATPase | 0.0341055 |
| KRT8 | keratin 8, type II | 0.033487 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0334365 |
| PPL | periplakin | 0.0333039 |
| UBC | ubiquitin C | 0.033276 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0328186 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0326913 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0323562 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0320136 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0319131 |
| ITGA6 | integrin, alpha 6 | 0.0318474 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.031662 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0312626 |
| AFDN | afadin, adherens junction formation factor | 0.0311633 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0307917 |
| ANLN | anillin, actin binding protein | 0.0301601 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0298754 |
| EFNB2 | ephrin-B2 | 0.029817 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0297026 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0295519 |
| SPATA13 | spermatogenesis associated 13 | 0.0292803 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0291966 |
| KRT19 | keratin 19, type I | 0.0291545 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0289149 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0287019 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0283642 |
| OGA | O-GlcNAcase | 0.0281841 |
| FLNB | filamin B, beta | 0.0280419 |
| VCL | vinculin | 0.0278877 |
| SETD5 | SET domain containing 5 | 0.0278406 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0277171 |
| GLG1 | golgi glycoprotein 1 | 0.0275735 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0273504 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0271676 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0269205 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.026859 |
| ABHD2 | abhydrolase domain containing 2 | 0.0266427 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.026642 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0265547 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0265513 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.026539 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0261648 |
| ATF4 | activating transcription factor 4 | 0.0257303 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0256934 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.025529 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0254134 |
| RPL14 | ribosomal protein L14 | 0.0252739 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0250649 |
| SERINC1 | serine incorporator 1 | 0.0249808 |
| ANXA11 | annexin A11 | 0.0249163 |
| APP | amyloid beta (A4) precursor protein | 0.0247907 |
| LAMB3 | laminin, beta 3 | 0.0247843 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0245017 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0244619 |
| ERBIN | erbb2 interacting protein | 0.0243685 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.15847 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.107027 |
| SYT1 | synaptotagmin I | -0.0623898 |
| WWOX | WW domain containing oxidoreductase | -0.0607848 |
| CDH13 | cadherin 13 | -0.052942 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0452407 |
| TMSB10 | thymosin beta 10 | -0.0451967 |
| RPL35A | ribosomal protein L35a | -0.0440748 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0414567 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0385502 |
| INTS6 | integrator complex subunit 6 | -0.0378028 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0374378 |
| CCND1 | cyclin D1 | -0.0373215 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0364912 |
| RAD51B | RAD51 paralog B | -0.035394 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0347293 |
| EGR1 | early growth response 1 | -0.0344584 |
| ACTG1 | actin gamma 1 | -0.0339283 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0338696 |
| RPL37A | ribosomal protein L37a | -0.0335734 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0325145 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.030907 |
| EXOC4 | exocyst complex component 4 | -0.0306175 |
| POTEF | POTE ankyrin domain family, member F | -0.0305517 |
| PTMA | prothymosin, alpha | -0.0300966 |
| HMGB1 | high mobility group box 1 | -0.0292206 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.029215 |
| PFN1 | profilin 1 | -0.0289128 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0271298 |
| CDK6 | cyclin-dependent kinase 6 | -0.0271135 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0263255 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0259393 |
| TMEM123 | transmembrane protein 123 | -0.0251998 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0243768 |
| DIAPH2 | diaphanous-related formin 2 | -0.0241359 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0233445 |
| RPLP1 | ribosomal protein, large, P1 | -0.022642 |
| FRMD5 | FERM domain containing 5 | -0.0225017 |
| HMGA1 | high mobility group AT-hook 1 | -0.0222664 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0222082 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0220433 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.022026 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0220171 |
| RPS6 | ribosomal protein S6 | -0.0215346 |
| GPHN | gephyrin | -0.0214875 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0214297 |
| RPL28 | ribosomal protein L28 | -0.0210496 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0209511 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0207714 |
| PHF14 | PHD finger protein 14 | -0.0204839 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0204512 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0204418 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0198643 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0197254 |
| FHIT | fragile histidine triad | -0.0194222 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0193108 |
| RPL5 | ribosomal protein L5 | -0.0187712 |
| PCDH9 | protocadherin 9 | -0.0179576 |
| RPS19 | ribosomal protein S19 | -0.0178541 |
| UBAP2 | ubiquitin associated protein 2 | -0.0178182 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0176695 |
| FUS | FUS RNA binding protein | -0.0174023 |
| AK1 | adenylate kinase 1 | -0.0172929 |
| RPL9 | ribosomal protein L9 | -0.0172853 |
| CBX3 | chromobox homolog 3 | -0.0171556 |
| ZNF207 | zinc finger protein 207 | -0.0169321 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0163844 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0159193 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.01589 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0157157 |
| CENPP | centromere protein P | -0.0157094 |
| SMYD3 | SET and MYND domain containing 3 | -0.0154491 |
| MTAP | methylthioadenosine phosphorylase | -0.015396 |
| RPS25 | ribosomal protein S25 | -0.0153526 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0153344 |
| RPL36 | ribosomal protein L36 | -0.0150657 |
| RCC1 | regulator of chromosome condensation 1 | -0.0150594 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0150333 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0150315 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0148861 |
| IER3 | immediate early response 3 | -0.0148382 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0147084 |
| HELLS | helicase, lymphoid-specific | -0.0146421 |
| AIG1 | androgen-induced 1 | -0.0146043 |
| TFRC | transferrin receptor | -0.0145473 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0144702 |
| TCF12 | transcription factor 12 | -0.0143976 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0143901 |
| RPL26 | ribosomal protein L26 | -0.0143749 |
| RTN3 | reticulon 3 | -0.0142313 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0139962 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0138329 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0138201 |
| RPS8 | ribosomal protein S8 | -0.0138027 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0136191 |
| ZFR | zinc finger RNA binding protein | -0.0135955 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0135643 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0135197 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0135154 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0132583 |
