Cryoglobulinemia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A condition characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins that precipitate within the microvasculature on exposure to cold; microvasculature effects of cryoglobulinemia may result in restricted tissue blood flow, tissue hypoxia, and tissue necrosis. --2004 (Experimental Factor Ontology, EFO_0005846)
External Link https://www.disgenet.org/browser/0/1/0/C0010403
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Genes

36 genes associated with the disease Cryoglobulinemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADK adenosine kinase
BCL2 B-cell CLL/lymphoma 2
BTG3 BTG family, member 3
CCL2 chemokine (C-C motif) ligand 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CRYGD crystallin, gamma D
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
IVNS1ABP influenza virus NS1A binding protein
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
LAG3 lymphocyte-activation gene 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NLRP3 NLR family, pyrin domain containing 3
NOTCH4 notch 4
NR1D2 nuclear receptor subfamily 1, group D, member 2
PAEP progestagen-associated endometrial protein
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TSLP thymic stromal lymphopoietin
VCAM1 vascular cell adhesion molecule 1
VIPR1 vasoactive intestinal peptide receptor 1