Cul2-RING ubiquitin ligase complex Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. (Gene Ontology, GO_0031462)
External Link http://amigo.geneontology.org/amigo/term/GO:0031462
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Genes

24 proteins localized to the Cul2-RING ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASB4 ankyrin repeat and SOCS box containing 4
COMMD1 copper metabolism (Murr1) domain containing 1
CUL2 cullin 2
ELOB elongin B
ELOC elongin C
FEM1A fem-1 homolog a (C. elegans)
FEM1B fem-1 homolog b (C. elegans)
FEM1C fem-1 homolog c (C. elegans)
GLMN glomulin, FKBP associated protein
KLHDC10 kelch domain containing 10
KLHDC2 kelch domain containing 2
KLHDC3 kelch domain containing 3
PRAME preferentially expressed antigen in melanoma
PRAMEF6 PRAME family member 6
PRAMEF9 PRAME family member 9
RBX1 ring-box 1, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator
ZSWIM4 zinc finger, SWIM-type containing 4
ZSWIM5 zinc finger, SWIM-type containing 5
ZSWIM6 zinc finger, SWIM-type containing 6
ZSWIM8 zinc finger, SWIM-type containing 8
ZYG11A zyg-11 family member A, cell cycle regulator
ZYG11B zyg-11 family member B, cell cycle regulator