Cul2-RING ubiquitin ligase complex Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. (Gene Ontology, GO_0031462)
External Link http://amigo.geneontology.org/amigo/term/GO:0031462
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Genes

45 proteins localized to the Cul2-RING ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ASB4 ankyrin repeat and SOCS box containing 4
COMMD1 copper metabolism (Murr1) domain containing 1
CUL2 cullin 2
ELOB elongin B
ELOC elongin C
FEM1B fem-1 homolog b (C. elegans)
FEM1C fem-1 homolog c (C. elegans)
GLMN glomulin, FKBP associated protein
KLHDC10 kelch domain containing 10
KLHDC2 kelch domain containing 2
KLHDC3 kelch domain containing 3
LRRC75A leucine rich repeat containing 75A
OTULIN-DT OTULIN divergent transcript
PRAME preferentially expressed antigen in melanoma
PRAMEF1 PRAME family member 1
PRAMEF10 PRAME family member 10
PRAMEF11 PRAME family member 11
PRAMEF12 PRAME family member 12
PRAMEF13 PRAME family member 13
PRAMEF14 PRAME family member 14
PRAMEF15 PRAME family member 15
PRAMEF17 PRAME family member 17
PRAMEF18 PRAME family member 18
PRAMEF19 PRAME family member 19
PRAMEF2 PRAME family member 2
PRAMEF20 PRAME family member 20
PRAMEF22 PRAME family member 22
PRAMEF26 PRAME family member 26
PRAMEF33 PRAME family member 33
PRAMEF4 PRAME family member 4
PRAMEF5 PRAME family member 5
PRAMEF6 PRAME family member 6
PRAMEF7 PRAME family member 7
PRAMEF8 PRAME family member 8
PRAMEF9 PRAME family member 9
RBX1 ring-box 1, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator
ZSWIM4 zinc finger, SWIM-type containing 4
ZSWIM5 zinc finger, SWIM-type containing 5
ZSWIM6 zinc finger, SWIM-type containing 6
ZSWIM8 zinc finger, SWIM-type containing 8
ZYG11A zyg-11 family member A, cell cycle regulator
ZYG11B zyg-11 family member B, cell cycle regulator