Cul4-RING E3 ubiquitin ligase complex Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. (Gene Ontology, GO_0080008)
External Link http://amigo.geneontology.org/amigo/term/GO:0080008
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Genes

37 proteins localized to the Cul4-RING E3 ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
AMBRA1 autophagy/beclin-1 regulator 1
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
CARD16 caspase recruitment domain family, member 16
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRBN cereblon
CUL4A cullin 4A
CUL4B cullin 4B
DCAF1 DDB1 and CUL4 associated factor 1
DCAF10 DDB1 and CUL4 associated factor 10
DCAF11 DDB1 and CUL4 associated factor 11
DCAF12 DDB1 and CUL4 associated factor 12
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1
DCAF12L2 DDB1 and CUL4 associated factor 12-like 2
DCAF13 DDB1 and CUL4 associated factor 13
DCAF15 DDB1 and CUL4 associated factor 15
DCAF16 DDB1 and CUL4 associated factor 16
DCAF17 DDB1 and CUL4 associated factor 17
DCAF4 DDB1 and CUL4 associated factor 4
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1
DCAF4L2 DDB1 and CUL4 associated factor 4-like 2
DCAF5 DDB1 and CUL4 associated factor 5
DCAF6 DDB1 and CUL4 associated factor 6
DCAF7 DDB1 and CUL4 associated factor 7
DCAF8 DDB1 and CUL4 associated factor 8
DCAF8L1 DDB1 and CUL4 associated factor 8-like 1
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2
DDA1 DET1 and DDB1 associated 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DET1 de-etiolated homolog 1 (Arabidopsis)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ERCC8 excision repair cross-complementation group 8
FBXW5 F-box and WD repeat domain containing 5
GLMN glomulin, FKBP associated protein
RBX1 ring-box 1, E3 ubiquitin protein ligase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
WDTC1 WD and tetratricopeptide repeats 1