Cul4A-RING E3 ubiquitin ligase complex Gene Set

Dataset	GO Cellular Component Annotations 2025
Category	structural or functional annotations
Type	cellular component
Description	A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein. (Gene Ontology, GO_0031464)
External Link	http://amigo.geneontology.org/amigo/term/GO:0031464
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14 proteins localized to the Cul4A-RING E3 ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol	Name
ARIH1	ariadne RBR E3 ubiquitin protein ligase 1
CARD16	caspase recruitment domain family, member 16
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRBN	cereblon
CUL4A	cullin 4A
CUL4B	cullin 4B
DDB1	damage-specific DNA binding protein 1, 127kDa
DDB2	damage-specific DNA binding protein 2, 48kDa
DET1	de-etiolated homolog 1 (Arabidopsis)
DTL	denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ERCC8	excision repair cross-complementation group 8
GLMN	glomulin, FKBP associated protein
RBX1	ring-box 1, E3 ubiquitin protein ligase
TRPC4AP	transient receptor potential cation channel, subfamily C, member 4 associated protein