Cul5-RING ubiquitin ligase complex Gene Set

Dataset	GO Cellular Component Annotations 2025
Category	structural or functional annotations
Type	cellular component
Description	A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein. (Gene Ontology, GO_0031466)
External Link	http://amigo.geneontology.org/amigo/term/GO:0031466
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Genes

15 proteins localized to the Cul5-RING ubiquitin ligase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol	Name
ANKRD9	ankyrin repeat domain 9
ARIH2	ariadne RBR E3 ubiquitin protein ligase 2
ASB11	ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB4	ankyrin repeat and SOCS box containing 4
ASB9	ankyrin repeat and SOCS box containing 9
CUL5	cullin 5
ELOB	elongin B
ELOC	elongin C
KLHDC1	kelch domain containing 1
PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
RBX1	ring-box 1, E3 ubiquitin protein ligase
RNF7	ring finger protein 7
SOCS2	suppressor of cytokine signaling 2
SOCS4	suppressor of cytokine signaling 4
SPSB3	splA/ryanodine receptor domain and SOCS box containing 3