Cushing Syndrome Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0010481
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Genes

121 genes associated with the disease Cushing Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
ACE angiotensin I converting enzyme
ACP5 acid phosphatase 5, tartrate resistant
ADRA2A adrenoceptor alpha 2A
AGRP agouti related neuropeptide
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APRT adenine phosphoribosyltransferase
ARMC5 armadillo repeat containing 5
ATR ATR serine/threonine kinase
AVP arginine vasopressin
BCOR BCL6 corepressor
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BRD2 bromodomain containing 2
C1QL1 complement component 1, q subcomponent-like 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAMP cathelicidin antimicrobial peptide
CCDC6 coiled-coil domain containing 6
CDH23 cadherin-related 23
CETP cholesteryl ester transfer protein, plasma
CGA glycoprotein hormones, alpha polypeptide
CGB chorionic gonadotropin, beta polypeptide
CGB5 chorionic gonadotropin, beta polypeptide 5
CGB8 chorionic gonadotropin, beta polypeptide 8
COASY CoA synthase
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPA1 carboxypeptidase A1 (pancreatic)
CRH corticotropin releasing hormone
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5A cytochrome b5 type A (microsomal)
CYBB cytochrome b-245, beta polypeptide
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DMD dystrophin
DRD2 dopamine receptor D2
DST dystonin
E2F1 E2F transcription factor 1
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FASN fatty acid synthase
FBXO32 F-box protein 32
FDX1 ferredoxin 1
FDXR ferredoxin reductase
FH fumarate hydratase
FKBP5 FK506 binding protein 5
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXO3 forkhead box O3
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GNAS GNAS complex locus
GSTA1 glutathione S-transferase alpha 1
HDAC9 histone deacetylase 9
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL18 interleukin 18
IL6 interleukin 6
IRF6 interferon regulatory factor 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KRT20 keratin 20, type I
KRT5 keratin 5, type II
LEP leptin
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LHCGR luteinizing hormone/choriogonadotropin receptor
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEN1 multiple endocrine neoplasia I
MFAP1 microfibrillar-associated protein 1
NDRG2 NDRG family member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
PDE11A phosphodiesterase 11A
PDE8B phosphodiesterase 8B
PECAM1 platelet/endothelial cell adhesion molecule 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMPCA peptidase (mitochondrial processing) alpha
POMC proopiomelanocortin
POR P450 (cytochrome) oxidoreductase
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
REN renin
RET ret proto-oncogene
SCARB1 scavenger receptor class B, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOST sclerostin
SST somatostatin
STAR steroidogenic acute regulatory protein
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TP53 tumor protein p53
TSC22D3 TSC22 domain family, member 3
TWIST1 twist family bHLH transcription factor 1
TXN thioredoxin
TXNIP thioredoxin interacting protein
USP8 ubiquitin specific peptidase 8
UTS2 urotensin 2
VWF von Willebrand factor