Cyanuric chloride Gene Set

Dataset DeepCoverMOA Drug Mechanisms of Action
Category proteomics
Type drug perturbation
External Link https://pubchem.ncbi.nlm.nih.gov/compound/7954
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Genes

200 proteins with high or low expression in Cyanuric chloride relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

high expression

Symbol Name Standardized Value
TRMO tRNA methyltransferase O 0.65
ZBTB39 zinc finger and BTB domain containing 39 0.57
BORA bora, aurora kinase A activator 0.55
ZNF397 zinc finger protein 397 0.49
RNF115 ring finger protein 115 0.48
USP27X ubiquitin specific peptidase 27, X-linked 0.44
TANGO2 transport and golgi organization 2 homolog (Drosophila) 0.43
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.42
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.42
CD320 CD320 molecule 0.41
SELENOH selenoprotein H 0.41
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 0.39
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 0.38
CEP72 centrosomal protein 72kDa 0.38
SLC25A44 solute carrier family 25, member 44 0.38
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.37
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.36
RXRA retinoid X receptor, alpha 0.36
ENO1 enolase 1, (alpha) 0.35
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.34
DSE dermatan sulfate epimerase 0.34
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 0.33
LRRIQ1 leucine-rich repeats and IQ motif containing 1 0.33
ZNF436 zinc finger protein 436 0.33
RGPD8 RANBP2-like and GRIP domain containing 8 0.33
RAB20 RAB20, member RAS oncogene family 0.33
SCAI suppressor of cancer cell invasion 0.32
DPP4 dipeptidyl-peptidase 4 0.32
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.32
PCGF5 polycomb group ring finger 5 0.32
AEN apoptosis enhancing nuclease 0.31
TRAF5 TNF receptor-associated factor 5 0.31
SPC24 SPC24, NDC80 kinetochore complex component 0.31
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino 0.31
DERPC DERPC proline and glycine rich nuclear protein 0.31
ZNF146 zinc finger protein 146 0.31
GPX4 glutathione peroxidase 4 0.3
NKAPD1 NKAP domain containing 1 0.3
MYADM myeloid-associated differentiation marker 0.3
UBAP1 ubiquitin associated protein 1 0.29
TMOD1 tropomodulin 1 0.29
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.29
COL14A1 collagen, type XIV, alpha 1 0.28
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.28
GPX1 glutathione peroxidase 1 0.28
SNRPF small nuclear ribonucleoprotein polypeptide F 0.28
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.28
GSE1 Gse1 coiled-coil protein 0.28
EMC10 ER membrane protein complex subunit 10 0.27
ZNF91 zinc finger protein 91 0.27
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 0.27
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.27
RNF185 ring finger protein 185 0.27
ZNF564 zinc finger protein 564 0.27
ASB7 ankyrin repeat and SOCS box containing 7 0.27
ZNF525 zinc finger protein 525 0.26
ZNF696 zinc finger protein 696 0.26
DOLPP1 dolichyldiphosphatase 1 0.26
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 0.26
NF1 neurofibromin 1 0.26
KMT2C lysine (K)-specific methyltransferase 2C 0.26
PNPLA8 patatin-like phospholipase domain containing 8 0.26
NTHL1 nth endonuclease III-like 1 (E. coli) 0.26
DPYSL4 dihydropyrimidinase-like 4 0.25
SON SON DNA binding protein 0.25
IGFBP5 insulin-like growth factor binding protein 5 0.25
ZNF711 zinc finger protein 711 0.25
TTC7A tetratricopeptide repeat domain 7A 0.24
ZNF561 zinc finger protein 561 0.24
RAP1B RAP1B, member of RAS oncogene family 0.24
PRRX2 paired related homeobox 2 0.24
MAP2 microtubule-associated protein 2 0.24
EPHA5 EPH receptor A5 0.24
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase 0.23
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.23
MBNL2 muscleblind-like splicing regulator 2 0.23
ZNF197 zinc finger protein 197 0.23
TULP3 tubby like protein 3 0.23
GREB1L growth regulation by estrogen in breast cancer-like 0.23
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 0.23
METTL6 methyltransferase like 6 0.23
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 0.23
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.23
POMT2 protein-O-mannosyltransferase 2 0.23
ZRANB1 zinc finger, RAN-binding domain containing 1 0.23
ZFP36 ZFP36 ring finger protein 0.22
TMEM242 transmembrane protein 242 0.22
ABHD17B abhydrolase domain containing 17B 0.22
N4BP3 NEDD4 binding protein 3 0.22
BHLHA15 basic helix-loop-helix family, member a15 0.22
ZNF174 zinc finger protein 174 0.22
ZNF239 zinc finger protein 239 0.22
ZCCHC10 zinc finger, CCHC domain containing 10 0.22
TADA2A transcriptional adaptor 2A 0.22
FBXL16 F-box and leucine-rich repeat protein 16 0.22
NABP2 nucleic acid binding protein 2 0.22
ANAPC10 anaphase promoting complex subunit 10 0.22
KCTD20 potassium channel tetramerization domain containing 20 0.22
CNTNAP1 contactin associated protein 1 0.22
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 0.21

low expression

Symbol Name Standardized Value
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -1.8
EPDR1 ependymin related 1 -0.7
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.68
ZNF12 zinc finger protein 12 -0.64
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -0.63
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.6
FBXO41 F-box protein 41 -0.58
FAM241A family with sequence similarity 241 member A -0.55
TOR2A torsin family 2, member A -0.52
SHFL shiftless antiviral inhibitor of ribosomal frameshifting -0.47
ZFYVE28 zinc finger, FYVE domain containing 28 -0.47
SBSN suprabasin -0.45
UST uronyl-2-sulfotransferase -0.43
MPZL2 myelin protein zero-like 2 -0.43
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.42
CEBPZOS CEBPZ opposite strand -0.42
RAB30 RAB30, member RAS oncogene family -0.41
ZNF646 zinc finger protein 646 -0.4
NPDC1 neural proliferation, differentiation and control, 1 -0.4
WNT16 wingless-type MMTV integration site family, member 16 -0.39
LIME1 Lck interacting transmembrane adaptor 1 -0.39
CENPB centromere protein B, 80kDa -0.39
PRF1 perforin 1 (pore forming protein) -0.38
INHBA inhibin, beta A -0.38
FBXO33 F-box protein 33 -0.38
TM9SF3 transmembrane 9 superfamily member 3 -0.38
FRS2 fibroblast growth factor receptor substrate 2 -0.37
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -0.37
PRELID3B PRELI domain containing 3B -0.37
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.37
SIDT2 SID1 transmembrane family, member 2 -0.36
SNAI1 snail family zinc finger 1 -0.35
AP5S1 adaptor-related protein complex 5, sigma 1 subunit -0.35
TMEM219 transmembrane protein 219 -0.35
NDFIP1 Nedd4 family interacting protein 1 -0.34
GLRX glutaredoxin (thioltransferase) -0.33
PCSK9 proprotein convertase subtilisin/kexin type 9 -0.33
MAN2C1 mannosidase, alpha, class 2C, member 1 -0.32
TMEM51 transmembrane protein 51 -0.32
TCEA2 transcription elongation factor A (SII), 2 -0.32
THAP9 THAP domain containing 9 -0.32
CPE carboxypeptidase E -0.31
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 -0.31
TBP TATA box binding protein -0.31
NCOR1 nuclear receptor corepressor 1 -0.3
ZBED2 zinc finger, BED-type containing 2 -0.29
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -0.29
TM7SF2 transmembrane 7 superfamily member 2 -0.29
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast) -0.29
FAM133A family with sequence similarity 133, member A -0.29
INO80D INO80 complex subunit D -0.28
FBXL15 F-box and leucine-rich repeat protein 15 -0.28
SATB1 SATB homeobox 1 -0.28
GAB1 GRB2-associated binding protein 1 -0.28
CERS2 ceramide synthase 2 -0.28
CPEB3 cytoplasmic polyadenylation element binding protein 3 -0.27
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.27
ACTBL2 actin, beta-like 2 -0.27
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.27
ISOC2 isochorismatase domain containing 2 -0.27
CLDN7 claudin 7 -0.26
ADCK1 aarF domain containing kinase 1 -0.26
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.26
TXNDC16 thioredoxin domain containing 16 -0.26
PEX11B peroxisomal biogenesis factor 11 beta -0.26
DMWD dystrophia myotonica, WD repeat containing -0.26
GRID1 glutamate receptor, ionotropic, delta 1 -0.25
NCOA4 nuclear receptor coactivator 4 -0.25
COL6A3 collagen, type VI, alpha 3 -0.25
ADCY9 adenylate cyclase 9 -0.25
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.25
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -0.25
ZNF652 zinc finger protein 652 -0.25
TMLHE trimethyllysine hydroxylase, epsilon -0.24
NHSL1 NHS-like 1 -0.24
JARID2 jumonji, AT rich interactive domain 2 -0.24
ZNF496 zinc finger protein 496 -0.24
SATB2 SATB homeobox 2 -0.24
TACSTD2 tumor-associated calcium signal transducer 2 -0.24
COL6A6 collagen, type VI, alpha 6 -0.24
TMEM185B transmembrane protein 185B -0.24
HIST1H1T histone cluster 1, H1t -0.24
LYRM7 LYR motif containing 7 -0.24
ZBED5 zinc finger, BED-type containing 5 -0.24
BCL7B B-cell CLL/lymphoma 7B -0.24
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 -0.24
MISP3 MISP family member 3 -0.23
CAB39L calcium binding protein 39-like -0.23
MEST mesoderm specific transcript -0.23
COA7 cytochrome c oxidase assembly factor 7 (putative) -0.23
TADA2B transcriptional adaptor 2B -0.23
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.23
MKNK1 MAP kinase interacting serine/threonine kinase 1 -0.23
ABHD11 abhydrolase domain containing 11 -0.23
CCNDBP1 cyclin D-type binding-protein 1 -0.22
AGTRAP angiotensin II receptor-associated protein -0.22
FAM110C family with sequence similarity 110, member C -0.22
CALD1 caldesmon 1 -0.22
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) -0.22
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.22