| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.150258 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0959388 |
| NDRG1 | N-myc downstream regulated 1 | 0.0910278 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0851948 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.078661 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0747397 |
| VEGFA | vascular endothelial growth factor A | 0.0701908 |
| ARRDC3 | arrestin domain containing 3 | 0.0677718 |
| SMAD3 | SMAD family member 3 | 0.0667525 |
| SEPTIN9 | septin 9 | 0.0601328 |
| IRS2 | insulin receptor substrate 2 | 0.0582504 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0564744 |
| GOLGA4 | golgin A4 | 0.0564659 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0560981 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0557845 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0556915 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0548156 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0536166 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0529321 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0528809 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0524427 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0516632 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0516083 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0504743 |
| NAV2 | neuron navigator 2 | 0.050242 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0501979 |
| ITGAV | integrin, alpha V | 0.0499739 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0499476 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0497761 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0489694 |
| APP | amyloid beta (A4) precursor protein | 0.0489363 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0488866 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0480383 |
| ATP13A3 | ATPase type 13A3 | 0.0470006 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0464182 |
| FLNA | filamin A, alpha | 0.0452894 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0446636 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0441455 |
| FAT1 | FAT atypical cadherin 1 | 0.0437604 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0431306 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0427085 |
| PTK2 | protein tyrosine kinase 2 | 0.0426721 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0415795 |
| DENND2B | DENN domain containing 2B | 0.041506 |
| MSN | moesin | 0.0412235 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0406891 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0401254 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0401071 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0385838 |
| COPA | coatomer protein complex, subunit alpha | 0.0381151 |
| COG5 | component of oligomeric golgi complex 5 | 0.0369068 |
| PLEC | plectin | 0.0368461 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0364683 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0363746 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.036247 |
| WDR43 | WD repeat domain 43 | 0.0356823 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0355516 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0351396 |
| SBF2 | SET binding factor 2 | 0.0345166 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0341188 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.033699 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0335727 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.033544 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0334604 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0330828 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0330447 |
| DENND4C | DENN/MADD domain containing 4C | 0.0330433 |
| RUNX1 | runt-related transcription factor 1 | 0.0328281 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0326689 |
| RHEB | Ras homolog enriched in brain | 0.0323366 |
| CLINT1 | clathrin interactor 1 | 0.0322221 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0320849 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0320301 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0312828 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0312008 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0311143 |
| FMNL2 | formin-like 2 | 0.0309791 |
| HPCAL1 | hippocalcin-like 1 | 0.0308306 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.030586 |
| CTBP2 | C-terminal binding protein 2 | 0.0302727 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0301954 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0301637 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0300425 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.029829 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0298252 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0295436 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.029471 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291309 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0290415 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0289252 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0289005 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0284894 |
| CANX | calnexin | 0.0284212 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0284159 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0282552 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.028172 |
| SQSTM1 | sequestosome 1 | 0.0280395 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0279873 |
| SEPTIN2 | septin 2 | 0.0278596 |
| CADM1 | cell adhesion molecule 1 | 0.0278404 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.242658 |
| FRMD4A | FERM domain containing 4A | -0.210992 |
| GPC6 | glypican 6 | -0.105283 |
| ASPH | aspartate beta-hydroxylase | -0.0988019 |
| CP | ceruloplasmin (ferroxidase) | -0.0818696 |
| RAI14 | retinoic acid induced 14 | -0.0647879 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0596097 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0592948 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0546781 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0541163 |
| GLIS3 | GLIS family zinc finger 3 | -0.0436065 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0415687 |
| RIGI | RNA sensor RIG-I | -0.0410361 |
| EHBP1 | EH domain binding protein 1 | -0.040317 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0385432 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0380823 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0366384 |
| TMSB10 | thymosin beta 10 | -0.0355929 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0348134 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0345274 |
| RRBP1 | ribosome binding protein 1 | -0.0325131 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0324302 |
| IFI44L | interferon-induced protein 44-like | -0.0322866 |
| VCL | vinculin | -0.0320521 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.031694 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0312223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0304368 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0302118 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0295022 |
| FAM107B | family with sequence similarity 107, member B | -0.0291652 |
| MX1 | MX dynamin-like GTPase 1 | -0.0289175 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0287396 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.028568 |
| RNF213 | ring finger protein 213 | -0.0281578 |
| EXOC4 | exocyst complex component 4 | -0.0281129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0276738 |
| SCFD2 | sec1 family domain containing 2 | -0.0273809 |
| BNC2 | basonuclin 2 | -0.027349 |
| SP100 | SP100 nuclear antigen | -0.0269908 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0263444 |
| RND3 | Rho family GTPase 3 | -0.0251441 |
| EFNA5 | ephrin-A5 | -0.0246575 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0242026 |
| DIAPH3 | diaphanous-related formin 3 | -0.0241041 |
| CTSD | cathepsin D | -0.0238723 |
| EGFR | epidermal growth factor receptor | -0.0236608 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0233727 |
| RRM2 | ribonucleotide reductase M2 | -0.023247 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0232233 |
| TPM4 | tropomyosin 4 | -0.022758 |
| RAD51B | RAD51 paralog B | -0.0226627 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0225564 |
| DGKI | diacylglycerol kinase, iota | -0.0224137 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0222493 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0221196 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0216336 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0213403 |
| PTH2R | parathyroid hormone 2 receptor | -0.0212076 |
| OSMR | oncostatin M receptor | -0.0211501 |
| DIAPH2 | diaphanous-related formin 2 | -0.0210117 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0205357 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0203872 |
| XAF1 | XIAP associated factor 1 | -0.0203346 |
| HLA-E | major histocompatibility complex, class I, E | -0.01994 |
| CLMP | CXADR-like membrane protein | -0.019608 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0194966 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0194466 |
| MMP7 | matrix metallopeptidase 7 | -0.0193018 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0192127 |
| VIM | vimentin | -0.0190514 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0185717 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0182691 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0181556 |
| EGR1 | early growth response 1 | -0.0180337 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0180179 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0179895 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.017977 |
| INTS6 | integrator complex subunit 6 | -0.0179549 |
| NABP1 | nucleic acid binding protein 1 | -0.0179054 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0177598 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0173715 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0173413 |
| OXR1 | oxidation resistance 1 | -0.0173352 |
| FN1 | fibronectin 1 | -0.0172437 |
| PRKCA | protein kinase C, alpha | -0.0171976 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0171773 |
| TENM3 | teneurin transmembrane protein 3 | -0.016901 |
| TUT7 | terminal uridylyl transferase 7 | -0.0167399 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0166695 |
| RBPMS | RNA binding protein with multiple splicing | -0.016651 |
| AHNAK | AHNAK nucleoprotein | -0.0165448 |
| MCL1 | myeloid cell leukemia 1 | -0.0164137 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0163588 |
| IFI44 | interferon-induced protein 44 | -0.0162689 |
| S100A11 | S100 calcium binding protein A11 | -0.0161915 |
| APOL1 | apolipoprotein L, 1 | -0.0161887 |
| MT2A | metallothionein 2A | -0.0161438 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | -0.0160752 |
| SORCS2 | sortilin-related VPS10 domain containing receptor 2 | -0.0160516 |
| ZNF644 | zinc finger protein 644 | -0.0159465 |
