| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.0921855 |
| NDRG1 | N-myc downstream regulated 1 | 0.0796414 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0773924 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0746174 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0696006 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0691306 |
| FLNB | filamin B, beta | 0.0624859 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0582035 |
| ANXA2 | annexin A2 | 0.043334 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0420896 |
| KRT18 | keratin 18, type I | 0.040969 |
| NAV2 | neuron navigator 2 | 0.0393163 |
| ACTG1 | actin gamma 1 | 0.0382422 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0371923 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0365957 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0352943 |
| FLNA | filamin A, alpha | 0.0351416 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0339533 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0336903 |
| VEGFA | vascular endothelial growth factor A | 0.0334965 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326089 |
| KLF6 | Kruppel-like factor 6 | 0.0314769 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0294532 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0289303 |
| MED15 | mediator complex subunit 15 | 0.0274799 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0269604 |
| FMNL2 | formin-like 2 | 0.0267891 |
| UPP1 | uridine phosphorylase 1 | 0.0263323 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0261296 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0254477 |
| MINK1 | misshapen-like kinase 1 | 0.0250075 |
| NONO | non-POU domain containing, octamer-binding | 0.0239687 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0236782 |
| RND3 | Rho family GTPase 3 | 0.0231498 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0228941 |
| RNF213 | ring finger protein 213 | 0.0228661 |
| MSN | moesin | 0.0226585 |
| RPL3 | ribosomal protein L3 | 0.0224805 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0220897 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0220553 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0220266 |
| SMTN | smoothelin | 0.0219953 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0219938 |
| SFTPA2 | surfactant protein A2 | 0.0219881 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0216304 |
| LAMC2 | laminin, gamma 2 | 0.0213936 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0211738 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0206592 |
| TNS1 | tensin 1 | 0.0204661 |
| PNN | pinin, desmosome associated protein | 0.0204467 |
| TBC1D22A | TBC1 domain family, member 22A | 0.020206 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0200306 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0196638 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0194713 |
| RASA2 | RAS p21 protein activator 2 | 0.0193538 |
| DAPK1 | death-associated protein kinase 1 | 0.0191545 |
| LAMB3 | laminin, beta 3 | 0.0191517 |
| ANXA5 | annexin A5 | 0.0190851 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0189678 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0189283 |
| C1D | C1D nuclear receptor corepressor | 0.0187464 |
| MSI2 | musashi RNA-binding protein 2 | 0.0186208 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0185796 |
| CTBP2 | C-terminal binding protein 2 | 0.0182677 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0181481 |
| ACTN1 | actinin, alpha 1 | 0.0180835 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0175823 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0174021 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0171696 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.017158 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0170862 |
| EFHD2 | EF-hand domain family, member D2 | 0.0168264 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0168241 |
| RPS10 | ribosomal protein S10 | 0.0166902 |
| DENND1A | DENN/MADD domain containing 1A | 0.0164475 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.015905 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0159046 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0158087 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.015708 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0155773 |
| PAQR5 | progestin and adipoQ receptor family member V | 0.0155404 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0155279 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0155264 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0154761 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0153237 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0152212 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0151836 |
| KLC1 | kinesin light chain 1 | 0.015125 |
| FRMD6 | FERM domain containing 6 | 0.0150788 |
| YBX1 | Y box binding protein 1 | 0.0149911 |
| SEPTIN2 | septin 2 | 0.014979 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0149259 |
| BCL2L1 | BCL2-like 1 | 0.01474 |
| WDR43 | WD repeat domain 43 | 0.0146187 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0145388 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0143855 |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 | 0.0142499 |
| ADAR | adenosine deaminase, RNA-specific | 0.0141456 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0141209 |
| ATP13A3 | ATPase type 13A3 | 0.0140846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197528 |
| UBC | ubiquitin C | -0.194028 |
| VIM | vimentin | -0.155645 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.130985 |
| MT2A | metallothionein 2A | -0.120666 |
| TMSB10 | thymosin beta 10 | -0.119139 |
| RPS27A | ribosomal protein S27a | -0.0993697 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0958448 |
| ASPH | aspartate beta-hydroxylase | -0.0779507 |
| LDHA | lactate dehydrogenase A | -0.0779287 |
| PCBP2 | poly(rC) binding protein 2 | -0.0743321 |
| MT1X | metallothionein 1X | -0.0727091 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.070985 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0698949 |
| TXNRD1 | thioredoxin reductase 1 | -0.0696982 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0679438 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0662973 |
| ENO1 | enolase 1, (alpha) | -0.0662424 |
| AHNAK | AHNAK nucleoprotein | -0.0633045 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0586518 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0567372 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0552877 |
| KYNU | kynureninase | -0.054774 |
| RPS16 | ribosomal protein S16 | -0.0535935 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0530493 |
| RPLP1 | ribosomal protein, large, P1 | -0.0484797 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0459998 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0454929 |
| RPL4 | ribosomal protein L4 | -0.044233 |
| RTN4 | reticulon 4 | -0.0424926 |
| FTL | ferritin, light polypeptide | -0.0419901 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0414188 |
| RPS24 | ribosomal protein S24 | -0.0410657 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0404473 |
| RPL23 | ribosomal protein L23 | -0.0397749 |
| CA12 | carbonic anhydrase XII | -0.0392472 |
| PKM | pyruvate kinase, muscle | -0.0389664 |
| RPS19 | ribosomal protein S19 | -0.0373917 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0356527 |
| S100A6 | S100 calcium binding protein A6 | -0.0351797 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0344096 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0335473 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0334265 |
| RPS6 | ribosomal protein S6 | -0.0320524 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0319 |
| VMP1 | vacuole membrane protein 1 | -0.0315835 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0312554 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0311476 |
| PDE10A | phosphodiesterase 10A | -0.030998 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308155 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0300937 |
| GRAMD1B | GRAM domain containing 1B | -0.0298365 |
| CENPF | centromere protein F, 350/400kDa | -0.0297773 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0293622 |
| CMIP | c-Maf inducing protein | -0.0292746 |
| RPL28 | ribosomal protein L28 | -0.0291149 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0285891 |
| MCL1 | myeloid cell leukemia 1 | -0.0279996 |
| RPS5 | ribosomal protein S5 | -0.0279288 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0278893 |
| AXL | AXL receptor tyrosine kinase | -0.0278185 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0275391 |
| POTEF | POTE ankyrin domain family, member F | -0.0272027 |
| FAM107B | family with sequence similarity 107, member B | -0.0263991 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0263879 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0260881 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0258016 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0256596 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0255996 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0244321 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0243649 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0243093 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0241065 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0240075 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239703 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0238857 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0233294 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0232631 |
| BPTF | bromodomain PHD finger transcription factor | -0.0232509 |
| OSMR | oncostatin M receptor | -0.0231652 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0230728 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0229698 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0226935 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0225605 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0221254 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.022089 |
| GLG1 | golgi glycoprotein 1 | -0.0214382 |
| GPC6 | glypican 6 | -0.0213746 |
| SMC4 | structural maintenance of chromosomes 4 | -0.020831 |
| GLIS3 | GLIS family zinc finger 3 | -0.020805 |
| RPL19 | ribosomal protein L19 | -0.020628 |
| LDHB | lactate dehydrogenase B | -0.0205721 |
| IPO7 | importin 7 | -0.0204877 |
| SMYD3 | SET and MYND domain containing 3 | -0.0200602 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0200113 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0196838 |
| MYO9A | myosin IXA | -0.019681 |
| EREG | epiregulin | -0.0196778 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0196749 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0193368 |
