| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cyclosporin A_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.227195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.130186 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0973478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0906719 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0808588 |
| RPL3 | ribosomal protein L3 | 0.0658553 |
| FLNB | filamin B, beta | 0.0572715 |
| EGR1 | early growth response 1 | 0.0567457 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0530139 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0466302 |
| FLNA | filamin A, alpha | 0.046151 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0447118 |
| FN1 | fibronectin 1 | 0.0443072 |
| PRELID2 | PRELI domain containing 2 | 0.0440369 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0429991 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0413886 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0403405 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0401848 |
| BBX | bobby sox homolog (Drosophila) | 0.0398506 |
| GSE1 | Gse1 coiled-coil protein | 0.0378921 |
| SIK3 | SIK family kinase 3 | 0.0377735 |
| FNIP1 | folliculin interacting protein 1 | 0.037056 |
| CDK19 | cyclin-dependent kinase 19 | 0.0358704 |
| DBN1 | drebrin 1 | 0.035807 |
| CEP250 | centrosomal protein 250kDa | 0.0356611 |
| TMSB4X | thymosin beta 4, X-linked | 0.0355807 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0353783 |
| MED13L | mediator complex subunit 13-like | 0.035057 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0348491 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0344007 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0341801 |
| QKI | QKI, KH domain containing, RNA binding | 0.0340583 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0338919 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0334575 |
| MEST | mesoderm specific transcript | 0.033278 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0325525 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.032502 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.032338 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0319254 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0316892 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0312588 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0308652 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0306157 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0305013 |
| ZNF516 | zinc finger protein 516 | 0.0304934 |
| SFTPA2 | surfactant protein A2 | 0.0303034 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0300186 |
| PLEC | plectin | 0.0295483 |
| RAD51B | RAD51 paralog B | 0.0295122 |
| KIF1A | kinesin family member 1A | 0.0293934 |
| MYOF | myoferlin | 0.0291119 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0287749 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0277141 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0273227 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0271102 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0270652 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0268321 |
| FAM13A | family with sequence similarity 13, member A | 0.0267382 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0266219 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0261567 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0257359 |
| NDRG1 | N-myc downstream regulated 1 | 0.0253976 |
| COPA | coatomer protein complex, subunit alpha | 0.0252671 |
| MED15 | mediator complex subunit 15 | 0.0248835 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0247509 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0246792 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0246534 |
| NUP58 | nucleoporin 58 | 0.0242042 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0241487 |
| APP | amyloid beta (A4) precursor protein | 0.0241391 |
| TRERF1 | transcriptional regulating factor 1 | 0.0241329 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.024086 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0238912 |
| NFYA | nuclear transcription factor Y, alpha | 0.0236451 |
| ATXN2L | ataxin 2-like | 0.0231865 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0231633 |
| RYBP | RING1 and YY1 binding protein | 0.0229583 |
| SMTN | smoothelin | 0.0227535 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0227317 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0225914 |
| EGFR | epidermal growth factor receptor | 0.0225639 |
| GSN | gelsolin | 0.0223924 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0223898 |
| NUDCD3 | NudC domain containing 3 | 0.0223397 |
| SQSTM1 | sequestosome 1 | 0.0218272 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0217191 |
| IGF2 | insulin-like growth factor 2 | 0.0214895 |
| PDE10A | phosphodiesterase 10A | 0.0214751 |
| PLS3 | plastin 3 | 0.0214289 |
| SKIL | SKI-like proto-oncogene | 0.0214183 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0213517 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0213423 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0211602 |
| FUS | FUS RNA binding protein | 0.0211159 |
| ZNF451 | zinc finger protein 451 | 0.021113 |
| CLEC16A | C-type lectin domain family 16, member A | 0.0210999 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0209734 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0208268 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.020774 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0207426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.261096 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130389 |
| PEG10 | paternally expressed 10 | -0.112672 |
| MGP | matrix Gla protein | -0.0906677 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0872386 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0870577 |
| RPLP1 | ribosomal protein, large, P1 | -0.0821344 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0813035 |
| TMSB10 | thymosin beta 10 | -0.0717634 |
| RPS6 | ribosomal protein S6 | -0.0676361 |
| RPS24 | ribosomal protein S24 | -0.0667623 |
| ENO1 | enolase 1, (alpha) | -0.0652841 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0639647 |
| PTMA | prothymosin, alpha | -0.0639309 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0605369 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0602597 |
| RPS8 | ribosomal protein S8 | -0.0573614 |
| RPL26 | ribosomal protein L26 | -0.0569868 |
| HMGB1 | high mobility group box 1 | -0.0559833 |
| RPS27A | ribosomal protein S27a | -0.0559007 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0526459 |
| UBC | ubiquitin C | -0.050868 |
| LDHA | lactate dehydrogenase A | -0.0501448 |
| RPLP2 | ribosomal protein, large, P2 | -0.0483539 |
| IER3 | immediate early response 3 | -0.0479838 |
| RPL12 | ribosomal protein L12 | -0.0467223 |
| RPS2 | ribosomal protein S2 | -0.0463548 |
| RBM25 | RNA binding motif protein 25 | -0.046082 |
| MT2A | metallothionein 2A | -0.0448978 |
| RPS4X | ribosomal protein S4, X-linked | -0.0445057 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0431425 |
| PCBP2 | poly(rC) binding protein 2 | -0.0429669 |
| RPL34 | ribosomal protein L34 | -0.0419796 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0405389 |
| DEK | DEK proto-oncogene | -0.0397216 |
| RPL23 | ribosomal protein L23 | -0.039313 |
| AHNAK | AHNAK nucleoprotein | -0.0366993 |
| FTL | ferritin, light polypeptide | -0.0363492 |
| RPL31 | ribosomal protein L31 | -0.035766 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0355476 |
| RPS20 | ribosomal protein S20 | -0.0353776 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0342757 |
| RPS23 | ribosomal protein S23 | -0.0339339 |
| HMGA2 | high mobility group AT-hook 2 | -0.0336449 |
| RPL36 | ribosomal protein L36 | -0.0335898 |
| RPL35A | ribosomal protein L35a | -0.0332593 |
| COL1A2 | collagen, type I, alpha 2 | -0.0330214 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0324533 |
| RANBP17 | RAN binding protein 17 | -0.0321333 |
| RPL28 | ribosomal protein L28 | -0.0317784 |
| ACTG1 | actin gamma 1 | -0.0314792 |
| RPS25 | ribosomal protein S25 | -0.0313373 |
| SEPTIN11 | septin 11 | -0.0310602 |
| CENPE | centromere protein E, 312kDa | -0.0310329 |
| RPS5 | ribosomal protein S5 | -0.031006 |
| RPS3 | ribosomal protein S3 | -0.0305443 |
| RPL37A | ribosomal protein L37a | -0.0303027 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0296421 |
| RPS14 | ribosomal protein S14 | -0.0296158 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.029199 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0288032 |
| RPL5 | ribosomal protein L5 | -0.0287769 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0285334 |
| S100A9 | S100 calcium binding protein A9 | -0.0285311 |
| EXOC6B | exocyst complex component 6B | -0.0284238 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0282582 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0280608 |
| YBX1 | Y box binding protein 1 | -0.0280207 |
| RPL13A | ribosomal protein L13a | -0.0277388 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0277074 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0275572 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0274632 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0273048 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0272139 |
| RPL8 | ribosomal protein L8 | -0.0271467 |
| CADM2 | cell adhesion molecule 2 | -0.0266694 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.026646 |
| RPS16 | ribosomal protein S16 | -0.0266189 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0265102 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.026441 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0263352 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0259496 |
| NOP58 | NOP58 ribonucleoprotein | -0.0257303 |
| RPS13 | ribosomal protein S13 | -0.0255196 |
| DUSP6 | dual specificity phosphatase 6 | -0.0252542 |
| RPS29 | ribosomal protein S29 | -0.0250559 |
| HMGA1 | high mobility group AT-hook 1 | -0.0249617 |
| RPS21 | ribosomal protein S21 | -0.0249032 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0247888 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0247875 |
| CENPF | centromere protein F, 350/400kDa | -0.0246524 |
| MATR3 | matrin 3 | -0.0245273 |
| RPL19 | ribosomal protein L19 | -0.0243888 |
| DIAPH3 | diaphanous-related formin 3 | -0.0242734 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0240703 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0240085 |
| PCM1 | pericentriolar material 1 | -0.0239907 |
| UBE3C | ubiquitin protein ligase E3C | -0.0238381 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0238315 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0235918 |
