| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.249381 |
| LAMB3 | laminin, beta 3 | 0.194892 |
| PLEC | plectin | 0.189045 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.170812 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.143539 |
| EZR | ezrin | 0.134493 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.129532 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.110698 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0968017 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0964402 |
| LAMA4 | laminin, alpha 4 | 0.0916884 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0882486 |
| KRT8 | keratin 8, type II | 0.0818141 |
| LAMC2 | laminin, gamma 2 | 0.0806201 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0800802 |
| EGR1 | early growth response 1 | 0.0800328 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0794899 |
| ANXA2 | annexin A2 | 0.0769377 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0757725 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0752441 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0738963 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0736623 |
| KRT18 | keratin 18, type I | 0.0704913 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0688001 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0675116 |
| NDRG1 | N-myc downstream regulated 1 | 0.0652065 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0651156 |
| LMO7 | LIM domain 7 | 0.0646272 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0643748 |
| PTMA | prothymosin, alpha | 0.0637913 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0612247 |
| ACTG1 | actin gamma 1 | 0.0609148 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0607722 |
| EGFR | epidermal growth factor receptor | 0.0599692 |
| ACTN4 | actinin, alpha 4 | 0.0579161 |
| SMAD3 | SMAD family member 3 | 0.0577175 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0576445 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.057155 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0568432 |
| MUC17 | mucin 17, cell surface associated | 0.0553584 |
| FAM107B | family with sequence similarity 107, member B | 0.05368 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0513934 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0513317 |
| TXNRD1 | thioredoxin reductase 1 | 0.0504126 |
| KLF6 | Kruppel-like factor 6 | 0.0486772 |
| UPP1 | uridine phosphorylase 1 | 0.0466592 |
| RCOR1 | REST corepressor 1 | 0.045709 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0443309 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0432657 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0423177 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.040944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0407846 |
| EPHA2 | EPH receptor A2 | 0.0404613 |
| DSPP | dentin sialophosphoprotein | 0.0403173 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0397892 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0397601 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.039709 |
| MXD1 | MAX dimerization protein 1 | 0.0391715 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0389663 |
| EMP1 | epithelial membrane protein 1 | 0.0388971 |
| VIM | vimentin | 0.0388393 |
| OSBP2 | oxysterol binding protein 2 | 0.0373067 |
| TPM3 | tropomyosin 3 | 0.0372502 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0362173 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0361379 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0355444 |
| B2M | beta-2-microglobulin | 0.0353796 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0351485 |
| TMSB10 | thymosin beta 10 | 0.0348755 |
| DIAPH1 | diaphanous-related formin 1 | 0.0348674 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0345377 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0345092 |
| FOSL1 | FOS-like antigen 1 | 0.0339743 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0338839 |
| RBM39 | RNA binding motif protein 39 | 0.033447 |
| MED15 | mediator complex subunit 15 | 0.0331784 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0331596 |
| PGK1 | phosphoglycerate kinase 1 | 0.0331066 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0326321 |
| SULF2 | sulfatase 2 | 0.0326012 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0325942 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0324813 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0322974 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0322039 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0320457 |
| OXSR1 | oxidative stress responsive 1 | 0.0316307 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.031309 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0311452 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0304884 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0302255 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301849 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0300454 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0297483 |
| APP | amyloid beta (A4) precursor protein | 0.0297417 |
| SQSTM1 | sequestosome 1 | 0.0295243 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0293587 |
| ARRDC3 | arrestin domain containing 3 | 0.0291547 |
| OGA | O-GlcNAcase | 0.0291242 |
| FSCN1 | fascin actin-bundling protein 1 | 0.028787 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0286678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS2 | ribosomal protein S2 | -0.0391887 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0309005 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0251976 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0225017 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0218775 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0204124 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.019716 |
| DSTN | destrin (actin depolymerizing factor) | -0.019216 |
| RPS6 | ribosomal protein S6 | -0.0185987 |
| RTN4 | reticulon 4 | -0.0172008 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0166212 |
| CDCP1 | CUB domain containing protein 1 | -0.0158374 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.01564 |
| FAM3C | family with sequence similarity 3, member C | -0.0156274 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0143091 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0141732 |
| TMEM165 | transmembrane protein 165 | -0.0138398 |
| RPL21 | ribosomal protein L21 | -0.0137026 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0133169 |
| RPL27A | ribosomal protein L27a | -0.0132559 |
| GOLGA4 | golgin A4 | -0.0132012 |
| HMGA1 | high mobility group AT-hook 1 | -0.0130639 |
| RPL9 | ribosomal protein L9 | -0.0125105 |
| RPS24 | ribosomal protein S24 | -0.0124856 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0123964 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0123531 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0118163 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0118071 |
| RPLP1 | ribosomal protein, large, P1 | -0.0117477 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0114658 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0114324 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0113238 |
| EFNA5 | ephrin-A5 | -0.0110401 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0109438 |
| CDK17 | cyclin-dependent kinase 17 | -0.0105165 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0102216 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0102151 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.010178 |
| RPS20 | ribosomal protein S20 | -0.0100596 |
| FTL | ferritin, light polypeptide | -0.0100239 |
| VCAN | versican | -0.0100081 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00993164 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0099228 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00989003 |
| DSG2 | desmoglein 2 | -0.00987621 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.00986411 |
| METTL15 | methyltransferase like 15 | -0.00984516 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00963924 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00953087 |
| RPS28 | ribosomal protein S28 | -0.00939852 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.00938879 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00926071 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0091983 |
| RPL39 | ribosomal protein L39 | -0.00917734 |
| PMP22 | peripheral myelin protein 22 | -0.00915908 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.00906772 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.00892604 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.00883379 |
| IFI44 | interferon-induced protein 44 | -0.00880209 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00879426 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00871084 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00858446 |
| FBXO28 | F-box protein 28 | -0.00857936 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.00857187 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00844099 |
| RPL28 | ribosomal protein L28 | -0.00842932 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.008386 |
| PRELID2 | PRELI domain containing 2 | -0.00835868 |
| TMEM123 | transmembrane protein 123 | -0.00834848 |
| RPLP2 | ribosomal protein, large, P2 | -0.00832549 |
| AK1 | adenylate kinase 1 | -0.00832251 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.00824504 |
| USP53 | ubiquitin specific peptidase 53 | -0.0081938 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.00818863 |
| SPIDR | scaffolding protein involved in DNA repair | -0.00818107 |
| PLS3 | plastin 3 | -0.00809881 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00807085 |
| TUBA1B | tubulin, alpha 1b | -0.00798948 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00790366 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00788253 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.00781863 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.00781765 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0077163 |
| RPL12 | ribosomal protein L12 | -0.0077051 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.00770281 |
| RPS16 | ribosomal protein S16 | -0.00765286 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 | -0.00757236 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00756345 |
| CEP170 | centrosomal protein 170kDa | -0.00752629 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0075067 |
| DEK | DEK proto-oncogene | -0.00749399 |
| ABHD17C | abhydrolase domain containing 17C | -0.00745544 |
| SMC4 | structural maintenance of chromosomes 4 | -0.00744716 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00743542 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00740928 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.00739475 |
| CRLS1 | cardiolipin synthase 1 | -0.00735967 |
| TASOR2 | transcription activation suppressor family member 2 | -0.00734283 |
| PKP4 | plakophilin 4 | -0.00726561 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0072637 |
