| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.204272 |
| NDRG1 | N-myc downstream regulated 1 | 0.11417 |
| CEP250 | centrosomal protein 250kDa | 0.113485 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0828852 |
| NCOA3 | nuclear receptor coactivator 3 | 0.076138 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0740098 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0672526 |
| VEGFA | vascular endothelial growth factor A | 0.0662522 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.064369 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.063353 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0628926 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0606616 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0559157 |
| RAB6A | RAB6A, member RAS oncogene family | 0.054252 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0535484 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0490435 |
| TPD52 | tumor protein D52 | 0.0476256 |
| FAM13A | family with sequence similarity 13, member A | 0.0423742 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.042314 |
| CCNY | cyclin Y | 0.0421926 |
| TMEM123 | transmembrane protein 123 | 0.0413502 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0406135 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0404872 |
| DTNA | dystrobrevin, alpha | 0.0390829 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0388403 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0382423 |
| ZNF292 | zinc finger protein 292 | 0.0377857 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0375145 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0373254 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0373139 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0368431 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0362586 |
| FLNB | filamin B, beta | 0.0361437 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.0359777 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.035862 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.035178 |
| COPA | coatomer protein complex, subunit alpha | 0.0349623 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0345706 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0333876 |
| SLC22A23 | solute carrier family 22, member 23 | 0.033368 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0332335 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0324979 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0317851 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0314283 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0313062 |
| SRP54 | signal recognition particle 54kDa | 0.0303206 |
| CANX | calnexin | 0.0302817 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0298272 |
| EGFR | epidermal growth factor receptor | 0.029781 |
| PLEC | plectin | 0.0289624 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0287344 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0286286 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0275222 |
| GOLGA4 | golgin A4 | 0.0274801 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0272559 |
| PRELID2 | PRELI domain containing 2 | 0.0271868 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0271428 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0271408 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0266348 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0265654 |
| SCFD1 | sec1 family domain containing 1 | 0.0261551 |
| KIF1A | kinesin family member 1A | 0.0261049 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0258571 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0258034 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0254913 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0254496 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0253199 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0252667 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0252535 |
| SQSTM1 | sequestosome 1 | 0.025102 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0249583 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0247397 |
| TMEM165 | transmembrane protein 165 | 0.0246907 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0245523 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.024463 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.024361 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0240758 |
| FNBP4 | formin binding protein 4 | 0.0240702 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0240674 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0239359 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0237341 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.023655 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0236495 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0232032 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 0.0231578 |
| MYO9B | myosin IXB | 0.0229216 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0225386 |
| FDPS | farnesyl diphosphate synthase | 0.0225068 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0224457 |
| FOXO3 | forkhead box O3 | 0.0224173 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0222546 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0219846 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.021966 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0218943 |
| USO1 | USO1 vesicle transport factor | 0.0218601 |
| INHBA | inhibin, beta A | 0.0217393 |
| RBM39 | RNA binding motif protein 39 | 0.0215393 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0213615 |
| FNIP1 | folliculin interacting protein 1 | 0.0210648 |
| TMEM41B | transmembrane protein 41B | 0.0209743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.240724 |
| RPL19 | ribosomal protein L19 | -0.168587 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.121001 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0843506 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0817824 |
| CDK12 | cyclin-dependent kinase 12 | -0.0732237 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0682373 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0581546 |
| ASPH | aspartate beta-hydroxylase | -0.056941 |
| TMSB10 | thymosin beta 10 | -0.0545076 |
| VMP1 | vacuole membrane protein 1 | -0.0532604 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0496982 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.045572 |
| S100A9 | S100 calcium binding protein A9 | -0.0423847 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0410369 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0399994 |
| SMYD3 | SET and MYND domain containing 3 | -0.0384413 |
| NTN4 | netrin 4 | -0.0372975 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0364123 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0347796 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.034675 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0340566 |
| POTEF | POTE ankyrin domain family, member F | -0.033672 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0315899 |
| RPS3 | ribosomal protein S3 | -0.0309841 |
| AHR | aryl hydrocarbon receptor | -0.0305444 |
| CCND1 | cyclin D1 | -0.0303176 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0302081 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301925 |
| RPL12 | ribosomal protein L12 | -0.0298673 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0296677 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0292496 |
| DUSP4 | dual specificity phosphatase 4 | -0.0289612 |
| PRR11 | proline rich 11 | -0.028586 |
| S100A8 | S100 calcium binding protein A8 | -0.0285142 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0283909 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0270204 |
| ENAH | enabled homolog (Drosophila) | -0.0266425 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0264532 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0250665 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0250184 |
| ACACA | acetyl-CoA carboxylase alpha | -0.024989 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0248284 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0248035 |
| OSMR | oncostatin M receptor | -0.0245311 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0241122 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0238452 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0238021 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0234844 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.0234047 |
| CD24 | CD24 molecule | -0.0232122 |
| RPL32 | ribosomal protein L32 | -0.0229657 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0228857 |
| MT2A | metallothionein 2A | -0.0227025 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0226259 |
| RPS8 | ribosomal protein S8 | -0.022592 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0223722 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0220925 |
| AUTS2 | autism susceptibility candidate 2 | -0.0220277 |
| TC2N | tandem C2 domains, nuclear | -0.0219875 |
| S100P | S100 calcium binding protein P | -0.0219085 |
| TUBA1B | tubulin, alpha 1b | -0.0213319 |
| RPL35A | ribosomal protein L35a | -0.0212286 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0210736 |
| CBX3 | chromobox homolog 3 | -0.0210255 |
| RPS24 | ribosomal protein S24 | -0.0208624 |
| FOXP1 | forkhead box P1 | -0.0207706 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0205837 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0204886 |
| RPS19 | ribosomal protein S19 | -0.0204264 |
| RPL11 | ribosomal protein L11 | -0.02019 |
| RPS21 | ribosomal protein S21 | -0.0198134 |
| SGMS1 | sphingomyelin synthase 1 | -0.0197598 |
| RPL35 | ribosomal protein L35 | -0.0196933 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.019658 |
| SYAP1 | synapse associated protein 1 | -0.0196556 |
| MED13L | mediator complex subunit 13-like | -0.019521 |
| RPS14 | ribosomal protein S14 | -0.0195008 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0194183 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0194134 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0193171 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0187436 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0186236 |
| RPS5 | ribosomal protein S5 | -0.0185013 |
| TTC6 | tetratricopeptide repeat domain 6 | -0.0184983 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0182363 |
| S100A14 | S100 calcium binding protein A14 | -0.0182362 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0182233 |
| RPS17 | ribosomal protein S17 | -0.018132 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0180172 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0178689 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0178134 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.017709 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0176763 |
| TPI1 | triosephosphate isomerase 1 | -0.0176547 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0176501 |
| CLDN7 | claudin 7 | -0.0176034 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0175702 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0175518 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0168285 |
