| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.111659 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.104401 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0969461 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0966229 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0949685 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0858546 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0626556 |
| NGLY1 | N-glycanase 1 | 0.0581766 |
| HELZ | helicase with zinc finger | 0.0572283 |
| RPL3 | ribosomal protein L3 | 0.056961 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0530832 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0529996 |
| CABIN1 | calcineurin binding protein 1 | 0.0522626 |
| DST | dystonin | 0.0511297 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0504615 |
| NUP58 | nucleoporin 58 | 0.0503797 |
| ARFGEF3 | ARFGEF family member 3 | 0.0491542 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0483436 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0478971 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0473766 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0469509 |
| EFNA5 | ephrin-A5 | 0.0468375 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0464265 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0461531 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0461143 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0458304 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0457437 |
| NEBL | nebulette | 0.0449743 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0442928 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0440875 |
| OGA | O-GlcNAcase | 0.0439296 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0435185 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0411107 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0409544 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0405209 |
| CDK19 | cyclin-dependent kinase 19 | 0.0403086 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0399313 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0384965 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.037694 |
| ATRN | attractin | 0.0368572 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.0366243 |
| FOXO3 | forkhead box O3 | 0.0363478 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.036132 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0356547 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0351848 |
| SMYD3 | SET and MYND domain containing 3 | 0.0347893 |
| RPLP0 | ribosomal protein, large, P0 | 0.0339949 |
| YEATS2 | YEATS domain containing 2 | 0.0339846 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0339255 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0327134 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0326497 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0321818 |
| PTCH1 | patched 1 | 0.0319682 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0318781 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0315457 |
| PTK2 | protein tyrosine kinase 2 | 0.0309009 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0302008 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0300732 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0296939 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0295096 |
| CEP250 | centrosomal protein 250kDa | 0.0294516 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.029318 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0293172 |
| TPM3 | tropomyosin 3 | 0.0290932 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.028727 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.028654 |
| FUS | FUS RNA binding protein | 0.0286531 |
| FAT1 | FAT atypical cadherin 1 | 0.0285877 |
| PNN | pinin, desmosome associated protein | 0.0282552 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0280606 |
| INSIG2 | insulin induced gene 2 | 0.0278276 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0277213 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0276856 |
| AUTS2 | autism susceptibility candidate 2 | 0.0275614 |
| CCNY | cyclin Y | 0.0275476 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0273196 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0270608 |
| VEGFA | vascular endothelial growth factor A | 0.0269053 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0266315 |
| ATP9A | ATPase, class II, type 9A | 0.0265246 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0263117 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0262597 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0262137 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0262081 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0260105 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0259341 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0256839 |
| KIAA1958 | KIAA1958 | 0.0256504 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0254161 |
| FLNA | filamin A, alpha | 0.0253995 |
| CANX | calnexin | 0.0252219 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.024891 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0248589 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0248526 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | 0.0247592 |
| NKTR | natural killer cell triggering receptor | 0.0247353 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0246902 |
| PDE8A | phosphodiesterase 8A | 0.0246843 |
| TENM2 | teneurin transmembrane protein 2 | 0.0242816 |
| KIF13A | kinesin family member 13A | 0.0242111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.143845 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.113134 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.101146 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0988995 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0731666 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0714428 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0643163 |
| RIGI | RNA sensor RIG-I | -0.0617795 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.054416 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0509215 |
| RAD51B | RAD51 paralog B | -0.0480365 |
| RPLP1 | ribosomal protein, large, P1 | -0.0468084 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0459032 |
| HMGB1 | high mobility group box 1 | -0.0421006 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0406177 |
| RPL12 | ribosomal protein L12 | -0.0391017 |
| VCL | vinculin | -0.0366767 |
| RPS24 | ribosomal protein S24 | -0.0331742 |
| MLIP | muscular LMNA-interacting protein | -0.0331472 |
| ZNF608 | zinc finger protein 608 | -0.0326845 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0323056 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0318923 |
| SHROOM3 | shroom family member 3 | -0.0307228 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0303917 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0302331 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0293218 |
| ZNF644 | zinc finger protein 644 | -0.0292462 |
| SETX | senataxin | -0.0290878 |
| TCF12 | transcription factor 12 | -0.0286792 |
| VMP1 | vacuole membrane protein 1 | -0.0275639 |
| RPS21 | ribosomal protein S21 | -0.026889 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0264974 |
| AHI1 | Abelson helper integration site 1 | -0.0264526 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0264157 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0260615 |
| PTMA | prothymosin, alpha | -0.0259894 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0255746 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0253401 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0251929 |
| RPL34 | ribosomal protein L34 | -0.0249558 |
| RPS2 | ribosomal protein S2 | -0.0249135 |
| VIM | vimentin | -0.0248423 |
| RPLP2 | ribosomal protein, large, P2 | -0.0247218 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0244119 |
| PHF14 | PHD finger protein 14 | -0.0243302 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0236227 |
| RPS6 | ribosomal protein S6 | -0.0235899 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0235876 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0231556 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0222232 |
| DCDC2 | doublecortin domain containing 2 | -0.0218313 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0216098 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0215578 |
| RPL35A | ribosomal protein L35a | -0.0215502 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0214806 |
| FBXO11 | F-box protein 11 | -0.0214601 |
| RPS20 | ribosomal protein S20 | -0.0211956 |
| NID1 | nidogen 1 | -0.0209646 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0208441 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0208341 |
| RPL19 | ribosomal protein L19 | -0.0207373 |
| PMP22 | peripheral myelin protein 22 | -0.0205525 |
| RPL28 | ribosomal protein L28 | -0.0204837 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.020283 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0200453 |
| RPS28 | ribosomal protein S28 | -0.0199204 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0198303 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0197516 |
| CADM2 | cell adhesion molecule 2 | -0.0196211 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0193433 |
| CBX3 | chromobox homolog 3 | -0.0192866 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0192204 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0191736 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.0191369 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.01897 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0188904 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.018788 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0187726 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0186747 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0183946 |
| RANBP17 | RAN binding protein 17 | -0.0183513 |
| RPL35 | ribosomal protein L35 | -0.0182936 |
| MAGEA4 | melanoma antigen family A4 | -0.0182491 |
| FHIT | fragile histidine triad | -0.0182484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0178834 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0175719 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0174104 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0173233 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0172934 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0171478 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0171432 |
| DTNB | dystrobrevin, beta | -0.0171174 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0171007 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0170674 |
| RPL31 | ribosomal protein L31 | -0.0168314 |
| TUBB4B | tubulin, beta 4B class IVb | -0.016741 |
| NOP56 | NOP56 ribonucleoprotein | -0.0167037 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0166216 |
| RERG | RAS-like, estrogen-regulated, growth inhibitor | -0.0164351 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0163995 |
