| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.123267 |
| FN1 | fibronectin 1 | 0.120416 |
| CD109 | CD109 molecule | 0.116121 |
| COPA | coatomer protein complex, subunit alpha | 0.0712273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0676703 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0628176 |
| CABIN1 | calcineurin binding protein 1 | 0.0618993 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0609451 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0605684 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0594607 |
| VGF | VGF nerve growth factor inducible | 0.0540813 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0538781 |
| NUP58 | nucleoporin 58 | 0.0518007 |
| VEGFA | vascular endothelial growth factor A | 0.0514482 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0491026 |
| INSIG1 | insulin induced gene 1 | 0.0490319 |
| NAV2 | neuron navigator 2 | 0.0489989 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.048892 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0475278 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0472688 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0460041 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0457108 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.044843 |
| NBAS | neuroblastoma amplified sequence | 0.0441381 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0432754 |
| ASPH | aspartate beta-hydroxylase | 0.0426555 |
| EGR1 | early growth response 1 | 0.0425803 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0420458 |
| APP | amyloid beta (A4) precursor protein | 0.0405198 |
| PTK2 | protein tyrosine kinase 2 | 0.0405034 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0392628 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0388273 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0375606 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0375147 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.037036 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0365823 |
| MRTFA | myocardin related transcription factor A | 0.0362754 |
| FLNB | filamin B, beta | 0.0361458 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0360992 |
| FMNL2 | formin-like 2 | 0.0360855 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0356823 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.035642 |
| SFTPA2 | surfactant protein A2 | 0.034863 |
| ACTN1 | actinin, alpha 1 | 0.0346515 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0344577 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0344128 |
| SETD5 | SET domain containing 5 | 0.034313 |
| ZYX | zyxin | 0.0336319 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0335677 |
| CDK19 | cyclin-dependent kinase 19 | 0.0333808 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0331463 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0331322 |
| PLEC | plectin | 0.0321317 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0319377 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.031825 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0314589 |
| PHF21A | PHD finger protein 21A | 0.0314285 |
| SEPTIN9 | septin 9 | 0.0306635 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0302885 |
| MED15 | mediator complex subunit 15 | 0.0302793 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0301122 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0298922 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0298357 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0296548 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0295563 |
| RBM33 | RNA binding motif protein 33 | 0.0292906 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0284279 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0282041 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0281146 |
| PKM | pyruvate kinase, muscle | 0.0277938 |
| PRELID2 | PRELI domain containing 2 | 0.0274769 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0274698 |
| EP300 | E1A binding protein p300 | 0.0274029 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0272735 |
| RPL3 | ribosomal protein L3 | 0.0272236 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0270058 |
| FLNA | filamin A, alpha | 0.0270002 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0268882 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0268381 |
| CDC73 | cell division cycle 73 | 0.0265577 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0264699 |
| POM121 | POM121 transmembrane nucleoporin | 0.0262106 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0255232 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0252622 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0247589 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.024727 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0244242 |
| SRPK2 | SRSF protein kinase 2 | 0.0242555 |
| AFDN | afadin, adherens junction formation factor | 0.0240894 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0240775 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0239528 |
| CEP250 | centrosomal protein 250kDa | 0.0239159 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0238415 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0237939 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0236752 |
| TMEM178B | transmembrane protein 178B | 0.0236072 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0235797 |
| HELZ | helicase with zinc finger | 0.0234873 |
| STXBP1 | syntaxin binding protein 1 | 0.0234808 |
| TPR | translocated promoter region, nuclear basket protein | 0.0233626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113772 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.085977 |
| VIM | vimentin | -0.0841139 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.081884 |
| NLGN1 | neuroligin 1 | -0.0597498 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0589434 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0569753 |
| TMSB10 | thymosin beta 10 | -0.045923 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0446159 |
| GPC6 | glypican 6 | -0.0412537 |
| IER3 | immediate early response 3 | -0.0375233 |
| MACROD2 | MACRO domain containing 2 | -0.036735 |
| NAV3 | neuron navigator 3 | -0.03487 |
| RPLP1 | ribosomal protein, large, P1 | -0.0310253 |
| FRMD4A | FERM domain containing 4A | -0.0306239 |
| S100A6 | S100 calcium binding protein A6 | -0.0283655 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0276917 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0273864 |
| HMCN1 | hemicentin 1 | -0.0241644 |
| MT2A | metallothionein 2A | -0.0210771 |
| FMN1 | formin 1 | -0.0208167 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0207969 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0202734 |
| AHNAK | AHNAK nucleoprotein | -0.0202044 |
| FRMD5 | FERM domain containing 5 | -0.0197358 |
| EHBP1 | EH domain binding protein 1 | -0.0196156 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0194308 |
| HMGA2 | high mobility group AT-hook 2 | -0.0190849 |
| TMEM123 | transmembrane protein 123 | -0.0182185 |
| DCT | dopachrome tautomerase | -0.0177466 |
| ACTG1 | actin gamma 1 | -0.0176393 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0173141 |
| PTMA | prothymosin, alpha | -0.0169357 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0169131 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0167807 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0166398 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0165936 |
| LSAMP | limbic system-associated membrane protein | -0.0164236 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.016196 |
| RPL35A | ribosomal protein L35a | -0.0160271 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0157063 |
| HMGB1 | high mobility group box 1 | -0.0156169 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0155106 |
| GNAS | GNAS complex locus | -0.0154084 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0152526 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0151542 |
| NPR2 | natriuretic peptide receptor 2 | -0.015153 |
| S100A9 | S100 calcium binding protein A9 | -0.0150543 |
| SCFD2 | sec1 family domain containing 2 | -0.0150398 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0150317 |
| NEGR1 | neuronal growth regulator 1 | -0.0149873 |
| NHSL1 | NHS-like 1 | -0.0146406 |
| CTSD | cathepsin D | -0.0145609 |
| PTCHD4 | patched domain containing 4 | -0.0144975 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0142452 |
| BSG | basigin (Ok blood group) | -0.0142439 |
| OSMR | oncostatin M receptor | -0.0141247 |
| NBEA | neurobeachin | -0.0140066 |
| FHIT | fragile histidine triad | -0.0139222 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0138319 |
| COL1A2 | collagen, type I, alpha 2 | -0.0134988 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0134116 |
| RPS24 | ribosomal protein S24 | -0.0133023 |
| AGMO | alkylglycerol monooxygenase | -0.0131311 |
| EBF1 | early B-cell factor 1 | -0.0130007 |
| CDK14 | cyclin-dependent kinase 14 | -0.0129979 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0129766 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0129444 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0127215 |
| FTL | ferritin, light polypeptide | -0.0125691 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0124417 |
| DMD | dystrophin | -0.0124277 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0123252 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0122743 |
| ATXN7L1 | ataxin 7-like 1 | -0.0121337 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0121079 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0120805 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0120576 |
| TNNC1 | troponin C type 1 (slow) | -0.0118574 |
| NRG1 | neuregulin 1 | -0.0116984 |
| PAX3 | paired box 3 | -0.0116612 |
| CENPF | centromere protein F, 350/400kDa | -0.011563 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0111254 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0110451 |
| HBP1 | HMG-box transcription factor 1 | -0.0108861 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0108683 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0106453 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0104957 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0104565 |
| RANBP17 | RAN binding protein 17 | -0.0104345 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0104097 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0103503 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0102178 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0101265 |
| CCND1 | cyclin D1 | -0.0101248 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0101021 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0100516 |
| FGF13 | fibroblast growth factor 13 | -0.00994893 |
| SSH2 | slingshot protein phosphatase 2 | -0.00982788 |
| NRXN3 | neurexin 3 | -0.00978932 |
