| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.160309 |
| LAMB3 | laminin, beta 3 | 0.151553 |
| VEGFA | vascular endothelial growth factor A | 0.135235 |
| NDRG1 | N-myc downstream regulated 1 | 0.131771 |
| PLAU | plasminogen activator, urokinase | 0.123712 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.109864 |
| FLNB | filamin B, beta | 0.102172 |
| PLEC | plectin | 0.101296 |
| APP | amyloid beta (A4) precursor protein | 0.0930177 |
| LAMC2 | laminin, gamma 2 | 0.0861599 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0834048 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0823131 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0788586 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0745448 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0738384 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0728339 |
| ANXA2 | annexin A2 | 0.0723405 |
| SPAG9 | sperm associated antigen 9 | 0.0688223 |
| SMAD3 | SMAD family member 3 | 0.0683247 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.065943 |
| ACTG1 | actin gamma 1 | 0.0655541 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0648186 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0647571 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0647239 |
| CCNY | cyclin Y | 0.0646607 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0645363 |
| FAM13A | family with sequence similarity 13, member A | 0.0642741 |
| TMSB4X | thymosin beta 4, X-linked | 0.0637486 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0630901 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0621958 |
| CALR | calreticulin | 0.0610909 |
| DTNA | dystrobrevin, alpha | 0.0605498 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0603446 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.059661 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0595133 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0591493 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.059081 |
| FLNA | filamin A, alpha | 0.0573468 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0568587 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0559167 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0538117 |
| KRT8 | keratin 8, type II | 0.0537383 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0515775 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.051359 |
| CANX | calnexin | 0.0513433 |
| RBM39 | RNA binding motif protein 39 | 0.0505532 |
| EZR | ezrin | 0.0492943 |
| KLF6 | Kruppel-like factor 6 | 0.0480922 |
| OGA | O-GlcNAcase | 0.046709 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0464379 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0464199 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0458464 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0457483 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0449443 |
| JUP | junction plakoglobin | 0.0446057 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0444697 |
| HPCAL1 | hippocalcin-like 1 | 0.0439406 |
| RACK1 | receptor for activated C kinase 1 | 0.0439247 |
| COPA | coatomer protein complex, subunit alpha | 0.0429438 |
| G0S2 | G0/G1 switch 2 | 0.0428613 |
| MYO5B | myosin VB | 0.0427983 |
| TSC22D2 | TSC22 domain family, member 2 | 0.042771 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0421291 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0419763 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0419513 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0417202 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0416383 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0407949 |
| PGK1 | phosphoglycerate kinase 1 | 0.0402094 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0400867 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0400164 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0391916 |
| KRT18 | keratin 18, type I | 0.0391628 |
| HELZ | helicase with zinc finger | 0.0391484 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0390608 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0390566 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0388779 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0388579 |
| ARRDC3 | arrestin domain containing 3 | 0.0386126 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0384786 |
| ANXA1 | annexin A1 | 0.0382579 |
| MED15 | mediator complex subunit 15 | 0.0375738 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0369924 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0367641 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0365632 |
| FOSL1 | FOS-like antigen 1 | 0.036081 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0359701 |
| LASP1 | LIM and SH3 protein 1 | 0.0355608 |
| WAC | WW domain containing adaptor with coiled-coil | 0.035448 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0354336 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0346535 |
| SFTPA2 | surfactant protein A2 | 0.0346456 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0342922 |
| JUN | jun proto-oncogene | 0.0341788 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0339999 |
| FUS | FUS RNA binding protein | 0.0339621 |
| MCL1 | myeloid cell leukemia 1 | 0.0338685 |
| ACTN1 | actinin, alpha 1 | 0.0338602 |
| CEP250 | centrosomal protein 250kDa | 0.0338268 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0335231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP7 | matrix metallopeptidase 7 | -0.102524 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0971321 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0897814 |
| MT2A | metallothionein 2A | -0.07142 |
| CP | ceruloplasmin (ferroxidase) | -0.0659561 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0618397 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0553864 |
| EFNA5 | ephrin-A5 | -0.054183 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0521601 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0472506 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0418695 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0392088 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0382862 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0357762 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0346625 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0320017 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0316835 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0313407 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0298228 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0297579 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0292428 |
| MX1 | MX dynamin-like GTPase 1 | -0.0284064 |
| APOL1 | apolipoprotein L, 1 | -0.0283975 |
| TMSB10 | thymosin beta 10 | -0.0281666 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0280469 |
| PCDH7 | protocadherin 7 | -0.0275034 |
| HMGA1 | high mobility group AT-hook 1 | -0.0275033 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0273056 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.027282 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0269548 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267028 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0263478 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0255953 |
| S100A6 | S100 calcium binding protein A6 | -0.0255414 |
| RPS2 | ribosomal protein S2 | -0.0253137 |
| MX2 | MX dynamin-like GTPase 2 | -0.0242663 |
| LCN2 | lipocalin 2 | -0.0240079 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0238091 |
| CDCP1 | CUB domain containing protein 1 | -0.023626 |
| OSMR | oncostatin M receptor | -0.023365 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0223521 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0219709 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0217214 |
| NRG3 | neuregulin 3 | -0.0215994 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0215484 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0210013 |
| PLAT | plasminogen activator, tissue | -0.0201955 |
| CSTB | cystatin B (stefin B) | -0.0200756 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0199769 |
| RAD51B | RAD51 paralog B | -0.019582 |
| RPS6 | ribosomal protein S6 | -0.0195292 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0191764 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.019028 |
| PMP22 | peripheral myelin protein 22 | -0.0190235 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0189271 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0186146 |
| S100A11 | S100 calcium binding protein A11 | -0.0185233 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0184551 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0183897 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0183162 |
| DSTN | destrin (actin depolymerizing factor) | -0.0182196 |
| TAPBP | TAP binding protein (tapasin) | -0.0180995 |
| RPS24 | ribosomal protein S24 | -0.0180837 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0179474 |
| BICC1 | BicC family RNA binding protein 1 | -0.0177472 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0173142 |
| FTL | ferritin, light polypeptide | -0.0172728 |
| DSG2 | desmoglein 2 | -0.0171496 |
| NABP1 | nucleic acid binding protein 1 | -0.0171025 |
| ITGA1 | integrin, alpha 1 | -0.0170963 |
| GLIS3 | GLIS family zinc finger 3 | -0.0168759 |
| RIGI | RNA sensor RIG-I | -0.0167702 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0166166 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.0165713 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0165437 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0164197 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0159329 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0157286 |
| SP100 | SP100 nuclear antigen | -0.0156682 |
| TMC5 | transmembrane channel-like 5 | -0.0156668 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0156163 |
| RPS19 | ribosomal protein S19 | -0.0156013 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0153315 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0153085 |
| ANTXR2 | anthrax toxin receptor 2 | -0.01517 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0150648 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0149479 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0148988 |
| RPL19 | ribosomal protein L19 | -0.0148035 |
| RPS29 | ribosomal protein S29 | -0.0144502 |
| UTRN | utrophin | -0.014399 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0142046 |
| XAF1 | XIAP associated factor 1 | -0.0140894 |
| RNF213 | ring finger protein 213 | -0.0140697 |
| EHBP1 | EH domain binding protein 1 | -0.0138375 |
| VCAN | versican | -0.0138242 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0138154 |
| IFI44L | interferon-induced protein 44-like | -0.0133883 |
| IFI44 | interferon-induced protein 44 | -0.0133497 |
| NRP1 | neuropilin 1 | -0.0132607 |
