| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.268665 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.11488 |
| NDRG1 | N-myc downstream regulated 1 | 0.104027 |
| VEGFA | vascular endothelial growth factor A | 0.0915883 |
| FAM13A | family with sequence similarity 13, member A | 0.0872312 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0858232 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0709447 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0699985 |
| WDR45B | WD repeat domain 45B | 0.0644673 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0623373 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0622672 |
| SEPTIN9 | septin 9 | 0.0594874 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0566682 |
| HELZ | helicase with zinc finger | 0.0539353 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0532936 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0516291 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0466213 |
| RPL3 | ribosomal protein L3 | 0.0446401 |
| COPA | coatomer protein complex, subunit alpha | 0.0431193 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0431118 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0424079 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0423316 |
| NUP58 | nucleoporin 58 | 0.0416865 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.041685 |
| LPIN1 | lipin 1 | 0.0416664 |
| PLEC | plectin | 0.0414868 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0411479 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0409451 |
| STC1 | stanniocalcin 1 | 0.0402983 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0398316 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0383382 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0361581 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.036053 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0358748 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0350611 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0350426 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0345891 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0336635 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0330695 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0328708 |
| SETD5 | SET domain containing 5 | 0.0324093 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0319352 |
| MEF2A | myocyte enhancer factor 2A | 0.0317062 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.031564 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0311438 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0308682 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0307133 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0305675 |
| TOP1 | topoisomerase (DNA) I | 0.0302304 |
| HMGB2 | high mobility group box 2 | 0.0300422 |
| FLNB | filamin B, beta | 0.0296525 |
| GPC5 | glypican 5 | 0.0290765 |
| SMAD3 | SMAD family member 3 | 0.0290272 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0284449 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0284243 |
| CANX | calnexin | 0.0284187 |
| ANXA2 | annexin A2 | 0.0283839 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0281934 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0279901 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279799 |
| YEATS2 | YEATS domain containing 2 | 0.0278445 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0271931 |
| TOB1 | transducer of ERBB2, 1 | 0.0271502 |
| USP36 | ubiquitin specific peptidase 36 | 0.026941 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0265485 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0264465 |
| MED15 | mediator complex subunit 15 | 0.0262782 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0261284 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0259572 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0258362 |
| VGF | VGF nerve growth factor inducible | 0.025491 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254866 |
| APP | amyloid beta (A4) precursor protein | 0.0252048 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0250831 |
| XPO1 | exportin 1 | 0.0250273 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0249413 |
| RARA | retinoic acid receptor, alpha | 0.0249257 |
| NONO | non-POU domain containing, octamer-binding | 0.0245581 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0244437 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0242451 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.02423 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0242197 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0241566 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0240151 |
| OGA | O-GlcNAcase | 0.0239977 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0239369 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.023837 |
| ARRDC3 | arrestin domain containing 3 | 0.0234868 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0234286 |
| NFYA | nuclear transcription factor Y, alpha | 0.0233305 |
| PKM | pyruvate kinase, muscle | 0.0232087 |
| DENND4C | DENN/MADD domain containing 4C | 0.0230728 |
| WDR43 | WD repeat domain 43 | 0.0228783 |
| SQSTM1 | sequestosome 1 | 0.0227239 |
| CASC3 | cancer susceptibility candidate 3 | 0.0227192 |
| MEF2D | myocyte enhancer factor 2D | 0.0223961 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0221263 |
| SET | SET nuclear proto-oncogene | 0.0220689 |
| DTNA | dystrobrevin, alpha | 0.0220507 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0220085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.243429 |
| LSAMP | limbic system-associated membrane protein | -0.154297 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153353 |
| SYT1 | synaptotagmin I | -0.115223 |
| VCL | vinculin | -0.103687 |
| FMN1 | formin 1 | -0.0919114 |
| RPS6 | ribosomal protein S6 | -0.0755829 |
| TLE4 | transducin-like enhancer of split 4 | -0.0750559 |
| RPLP1 | ribosomal protein, large, P1 | -0.0727227 |
| BPTF | bromodomain PHD finger transcription factor | -0.0713203 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0702429 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0684679 |
| RPS24 | ribosomal protein S24 | -0.0675645 |
| RPL35A | ribosomal protein L35a | -0.0609941 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0603253 |
| RPL34 | ribosomal protein L34 | -0.0583763 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.058231 |
| RPL38 | ribosomal protein L38 | -0.05702 |
| KLHL13 | kelch-like family member 13 | -0.0559653 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0553659 |
| RPL19 | ribosomal protein L19 | -0.0550972 |
| RPL23 | ribosomal protein L23 | -0.0521177 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0520863 |
| NREP | neuronal regeneration related protein | -0.0499525 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0497244 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0492055 |
| COL3A1 | collagen, type III, alpha 1 | -0.0491297 |
| VMP1 | vacuole membrane protein 1 | -0.0435367 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0430025 |
| PCDH9 | protocadherin 9 | -0.0422533 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0418363 |
| TMSB10 | thymosin beta 10 | -0.0416526 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0399947 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.039221 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0391743 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0386831 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0384983 |
| THBS1 | thrombospondin 1 | -0.0382059 |
| RPL31 | ribosomal protein L31 | -0.0379744 |
| RPS19 | ribosomal protein S19 | -0.0375941 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.037362 |
| PTMA | prothymosin, alpha | -0.0366018 |
| RPL12 | ribosomal protein L12 | -0.0361175 |
| RPS23 | ribosomal protein S23 | -0.0360484 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0355877 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.035549 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0352504 |
| RPL37A | ribosomal protein L37a | -0.0345275 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0340158 |
| MEIS2 | Meis homeobox 2 | -0.0339059 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0336682 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0331661 |
| RPS12 | ribosomal protein S12 | -0.0326634 |
| FTL | ferritin, light polypeptide | -0.0322591 |
| RPS2 | ribosomal protein S2 | -0.0317221 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0312861 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.030795 |
| ACTG1 | actin gamma 1 | -0.03043 |
| TCF12 | transcription factor 12 | -0.0303613 |
| S100A9 | S100 calcium binding protein A9 | -0.0303505 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0299541 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0297954 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0297263 |
| CCDC47 | coiled-coil domain containing 47 | -0.029706 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0295546 |
| DPH6 | diphthamine biosynthesis 6 | -0.0294898 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0294025 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0287064 |
| CNTN4 | contactin 4 | -0.0286603 |
| FHIT | fragile histidine triad | -0.028605 |
| RPL9 | ribosomal protein L9 | -0.0285977 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0284189 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0280249 |
| GPATCH8 | G patch domain containing 8 | -0.0279633 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0278217 |
| ZNF804A | zinc finger protein 804A | -0.0277994 |
| COL1A1 | collagen, type I, alpha 1 | -0.0277666 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0276279 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0274955 |
| RPL27 | ribosomal protein L27 | -0.0274535 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0273239 |
| PRKCA | protein kinase C, alpha | -0.0271876 |
| RPL32 | ribosomal protein L32 | -0.0268704 |
| RIGI | RNA sensor RIG-I | -0.0266565 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0266525 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0258975 |
| GATA3 | GATA binding protein 3 | -0.0258796 |
| RPS14 | ribosomal protein S14 | -0.025766 |
| IER3 | immediate early response 3 | -0.0256983 |
| RPL4 | ribosomal protein L4 | -0.0256941 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.025663 |
| RPS8 | ribosomal protein S8 | -0.0256381 |
| EFNA5 | ephrin-A5 | -0.0251756 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0250708 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249552 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0247354 |
| TRIB2 | tribbles pseudokinase 2 | -0.0246045 |
| TPM4 | tropomyosin 4 | -0.0245759 |
| AUTS2 | autism susceptibility candidate 2 | -0.0245016 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0243712 |
