| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.13622 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.10636 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0844837 |
| NDRG1 | N-myc downstream regulated 1 | 0.0797911 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0770611 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0688776 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0674378 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0639918 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0601669 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0594877 |
| TXNIP | thioredoxin interacting protein | 0.0593477 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0555893 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0555882 |
| CANX | calnexin | 0.0533822 |
| RNF149 | ring finger protein 149 | 0.0497799 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.048922 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0478808 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0475104 |
| VEGFA | vascular endothelial growth factor A | 0.0437413 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0429891 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0417633 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0406067 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0403824 |
| RUNX1 | runt-related transcription factor 1 | 0.0376006 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.037396 |
| COPA | coatomer protein complex, subunit alpha | 0.037279 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0361609 |
| CALR | calreticulin | 0.0353301 |
| PTEN | phosphatase and tensin homolog | 0.035153 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0350822 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0350274 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0350084 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0344479 |
| H1-0 | H1.0 linker histone | 0.034119 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.034057 |
| B2M | beta-2-microglobulin | 0.0338846 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0336627 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0336105 |
| AHI1 | Abelson helper integration site 1 | 0.0330738 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0315069 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0314975 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0309463 |
| RNF43 | ring finger protein 43 | 0.030809 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0305083 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0304469 |
| MKI67 | marker of proliferation Ki-67 | 0.0302428 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0296498 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0295247 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0294061 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0292206 |
| RAB1A | RAB1A, member RAS oncogene family | 0.029089 |
| DIAPH3 | diaphanous-related formin 3 | 0.0288463 |
| STK24 | serine/threonine kinase 24 | 0.0286647 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0282713 |
| OGA | O-GlcNAcase | 0.0280325 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0277899 |
| CLTC | clathrin, heavy chain (Hc) | 0.0276883 |
| FNIP1 | folliculin interacting protein 1 | 0.0275417 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0274368 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0271097 |
| DENND4C | DENN/MADD domain containing 4C | 0.0270547 |
| IL20RA | interleukin 20 receptor, alpha | 0.0268732 |
| HELZ | helicase with zinc finger | 0.0268609 |
| GOLGA4 | golgin A4 | 0.0268059 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0263655 |
| MEIS2 | Meis homeobox 2 | 0.0262989 |
| YEATS2 | YEATS domain containing 2 | 0.0261628 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0261589 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0258876 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0256988 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0256573 |
| SBF2 | SET binding factor 2 | 0.0255991 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0253731 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0253547 |
| FDPS | farnesyl diphosphate synthase | 0.0252402 |
| NEBL | nebulette | 0.025215 |
| RAB6A | RAB6A, member RAS oncogene family | 0.024881 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0248131 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0247044 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0244129 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0243394 |
| TMEM51 | transmembrane protein 51 | 0.0243271 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0238545 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0238489 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0237938 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237812 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0237386 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0236582 |
| TMEM39A | transmembrane protein 39A | 0.0236543 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0236113 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.023567 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0235021 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0234736 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0233936 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0233519 |
| SUCO | SUN domain containing ossification factor | 0.0232787 |
| AOPEP | aminopeptidase O (putative) | 0.0231641 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0230896 |
| ARGLU1 | arginine and glutamate rich 1 | 0.022859 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0227704 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.131805 |
| INTS6 | integrator complex subunit 6 | -0.110568 |
| RNF213 | ring finger protein 213 | -0.103284 |
| SP100 | SP100 nuclear antigen | -0.098378 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0966261 |
| RIGI | RNA sensor RIG-I | -0.0951468 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0948764 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0910773 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0887797 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0862989 |
| ANXA2 | annexin A2 | -0.0854068 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.083887 |
| VCL | vinculin | -0.0833038 |
| MX1 | MX dynamin-like GTPase 1 | -0.0796883 |
| PLSCR2 | phospholipid scramblase 2 | -0.0752896 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0727184 |
| LYZ | lysozyme | -0.0725372 |
| XAF1 | XIAP associated factor 1 | -0.0707316 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0672523 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0645136 |
| MX2 | MX dynamin-like GTPase 2 | -0.0642079 |
| NPSR1 | neuropeptide S receptor 1 | -0.0634762 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0611806 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0577416 |
| LCN2 | lipocalin 2 | -0.055542 |
| AREG | amphiregulin | -0.0540506 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0539618 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0494881 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0493755 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0487644 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0469844 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0466633 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0464704 |
| LMO7 | LIM domain 7 | -0.0462807 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0461264 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0453879 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0453357 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0447618 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0442312 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0418064 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0413495 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0404705 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0402134 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0391069 |
| MUC20 | mucin 20, cell surface associated | -0.0390996 |
| PMP22 | peripheral myelin protein 22 | -0.037902 |
| POF1B | premature ovarian failure, 1B | -0.0375481 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0370688 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0363532 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0362481 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.03617 |
| PLSCR1 | phospholipid scramblase 1 | -0.0360352 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0354422 |
| NABP1 | nucleic acid binding protein 1 | -0.0350727 |
| MCL1 | myeloid cell leukemia 1 | -0.034164 |
| ACTG1 | actin gamma 1 | -0.032629 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0311454 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0309942 |
| ETV6 | ets variant 6 | -0.0302518 |
| UBAP2 | ubiquitin associated protein 2 | -0.0295377 |
| TMSB10 | thymosin beta 10 | -0.0293982 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0290506 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0289196 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0287689 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0283885 |
| PERP | PERP, TP53 apoptosis effector | -0.0283361 |
| TNS4 | tensin 4 | -0.0282925 |
| FBXO39 | F-box protein 39 | -0.0279745 |
| LAMA4 | laminin, alpha 4 | -0.0275059 |
| PRKCA | protein kinase C, alpha | -0.0272221 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0271519 |
| NCOA7 | nuclear receptor coactivator 7 | -0.026035 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0260322 |
| PHF3 | PHD finger protein 3 | -0.026026 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0253646 |
| LAP3 | leucine aminopeptidase 3 | -0.0249394 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.024502 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0244423 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0239385 |
| FTL | ferritin, light polypeptide | -0.0238157 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.023595 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0235791 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0235407 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0228777 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0228242 |
| CUX1 | cut-like homeobox 1 | -0.0225398 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0225286 |
| IER3 | immediate early response 3 | -0.0223752 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0223328 |
| PTMA | prothymosin, alpha | -0.0222394 |
| POU2F2 | POU class 2 homeobox 2 | -0.0222279 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0221508 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0221235 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0220547 |
| BCL2L1 | BCL2-like 1 | -0.0219464 |
| USP53 | ubiquitin specific peptidase 53 | -0.0219205 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0217401 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0214176 |
| MSI2 | musashi RNA-binding protein 2 | -0.0212847 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0209791 |
