| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cyclosporin A_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.239957 |
| NDRG1 | N-myc downstream regulated 1 | 0.119224 |
| STC1 | stanniocalcin 1 | 0.0925638 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0838404 |
| HDAC9 | histone deacetylase 9 | 0.0833467 |
| CANX | calnexin | 0.0773667 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0716818 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0574089 |
| VEGFA | vascular endothelial growth factor A | 0.057254 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0559317 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0548271 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.053925 |
| FAM13A | family with sequence similarity 13, member A | 0.0539242 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0533325 |
| PLEC | plectin | 0.0511297 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0503393 |
| SMAD3 | SMAD family member 3 | 0.0493361 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0472367 |
| KYNU | kynureninase | 0.0443395 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0434091 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0430856 |
| ANKRD11 | ankyrin repeat domain 11 | 0.04208 |
| FLNA | filamin A, alpha | 0.039378 |
| OGA | O-GlcNAcase | 0.0388319 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0380573 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0375891 |
| COPA | coatomer protein complex, subunit alpha | 0.0365918 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0359566 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0356457 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0356227 |
| ASPH | aspartate beta-hydroxylase | 0.0354371 |
| LOXL2 | lysyl oxidase-like 2 | 0.0350471 |
| APP | amyloid beta (A4) precursor protein | 0.034973 |
| LRRC49 | leucine rich repeat containing 49 | 0.0346537 |
| FNIP1 | folliculin interacting protein 1 | 0.0346486 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0345505 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0343864 |
| ZNF160 | zinc finger protein 160 | 0.0339735 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0336918 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0333631 |
| COL5A1 | collagen, type V, alpha 1 | 0.03249 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0319176 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0316989 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0314389 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0313827 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0308237 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0304077 |
| ATP13A3 | ATPase type 13A3 | 0.0302227 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0300988 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300444 |
| MSN | moesin | 0.0300193 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0297674 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0297297 |
| PRELID2 | PRELI domain containing 2 | 0.0296324 |
| CLTC | clathrin, heavy chain (Hc) | 0.0294766 |
| YEATS2 | YEATS domain containing 2 | 0.0293557 |
| CD44 | CD44 molecule (Indian blood group) | 0.0293409 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0288554 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0287044 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0282262 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0282196 |
| CALU | calumenin | 0.0282191 |
| HDLBP | high density lipoprotein binding protein | 0.028215 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0281768 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0281721 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0280669 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0279629 |
| SEPTIN2 | septin 2 | 0.0279567 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0278331 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0269647 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0263797 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0260032 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0259272 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0257375 |
| CD109 | CD109 molecule | 0.025696 |
| JAK1 | Janus kinase 1 | 0.0256378 |
| ZNF841 | zinc finger protein 841 | 0.0252667 |
| FLNB | filamin B, beta | 0.0251955 |
| CALD1 | caldesmon 1 | 0.0250659 |
| HELZ | helicase with zinc finger | 0.0250219 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0248904 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.024783 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0246752 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0245996 |
| CADM1 | cell adhesion molecule 1 | 0.0244185 |
| ACTN1 | actinin, alpha 1 | 0.0243169 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0239357 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0239004 |
| TMEM39A | transmembrane protein 39A | 0.0238606 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0235907 |
| ANXA2 | annexin A2 | 0.0234721 |
| TXNIP | thioredoxin interacting protein | 0.02326 |
| SBF2 | SET binding factor 2 | 0.0232571 |
| SETD5 | SET domain containing 5 | 0.0225525 |
| ZNF292 | zinc finger protein 292 | 0.0221835 |
| TPM3 | tropomyosin 3 | 0.0219573 |
| AHNAK | AHNAK nucleoprotein | 0.0217642 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0217104 |
| SNX13 | sorting nexin 13 | 0.0217009 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0216158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.129834 |
| TMSB10 | thymosin beta 10 | -0.1258 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.102805 |
| VIM | vimentin | -0.0561302 |
| PTMA | prothymosin, alpha | -0.0528261 |
| FN1 | fibronectin 1 | -0.0526621 |
| RPS6 | ribosomal protein S6 | -0.0468538 |
| RPL35A | ribosomal protein L35a | -0.043114 |
| LDHA | lactate dehydrogenase A | -0.0423584 |
| MT2A | metallothionein 2A | -0.0414837 |
| POTEF | POTE ankyrin domain family, member F | -0.0393109 |
| TPM4 | tropomyosin 4 | -0.0392852 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.036672 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0354058 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0346003 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0345025 |
| RPS8 | ribosomal protein S8 | -0.0334615 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0317978 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0303057 |
| TPI1 | triosephosphate isomerase 1 | -0.0297316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0281837 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0276787 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0264513 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0260936 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0258096 |
| HLA-A | major histocompatibility complex, class I, A | -0.0252769 |
| MAP1B | microtubule-associated protein 1B | -0.0246957 |
| ATF4 | activating transcription factor 4 | -0.0239339 |
| EGR1 | early growth response 1 | -0.0238857 |
| RPL28 | ribosomal protein L28 | -0.0238388 |
| HLA-B | major histocompatibility complex, class I, B | -0.0237787 |
| GNAS | GNAS complex locus | -0.0236622 |
| HMGA1 | high mobility group AT-hook 1 | -0.0227696 |
| SCFD2 | sec1 family domain containing 2 | -0.0226541 |
| RPS19 | ribosomal protein S19 | -0.0224944 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0222942 |
| NLGN1 | neuroligin 1 | -0.0222856 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0221323 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0218664 |
| RPL31 | ribosomal protein L31 | -0.0212702 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0206878 |
| PFN1 | profilin 1 | -0.0203499 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0197413 |
| CBX3 | chromobox homolog 3 | -0.0197365 |
| DEK | DEK proto-oncogene | -0.01865 |
| S100A6 | S100 calcium binding protein A6 | -0.0181105 |
| ACTG1 | actin gamma 1 | -0.0179376 |
| RPL12 | ribosomal protein L12 | -0.0178812 |
| RPS5 | ribosomal protein S5 | -0.0173363 |
| RPS16 | ribosomal protein S16 | -0.0172545 |
| ENO1 | enolase 1, (alpha) | -0.0170773 |
| RPS21 | ribosomal protein S21 | -0.0169324 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0165656 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0163734 |
| SEC61G | Sec61 gamma subunit | -0.0161918 |
| RPLP2 | ribosomal protein, large, P2 | -0.0159749 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0158755 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0155147 |
| RPS20 | ribosomal protein S20 | -0.0154538 |
| CCND1 | cyclin D1 | -0.0154504 |
| RPL36 | ribosomal protein L36 | -0.0154309 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0153004 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0151615 |
| ZNF804A | zinc finger protein 804A | -0.014959 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0149519 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0149401 |
| VCL | vinculin | -0.0147602 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0147419 |
| RPL8 | ribosomal protein L8 | -0.0147303 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0145931 |
| DSTN | destrin (actin depolymerizing factor) | -0.0145913 |
| COL5A2 | collagen, type V, alpha 2 | -0.0145249 |
| NOP58 | NOP58 ribonucleoprotein | -0.0143571 |
| TAPBP | TAP binding protein (tapasin) | -0.0142777 |
| AHR | aryl hydrocarbon receptor | -0.0142709 |
| B2M | beta-2-microglobulin | -0.0142113 |
| PRSS23 | protease, serine, 23 | -0.0141775 |
| RPS3 | ribosomal protein S3 | -0.014171 |
| CTSD | cathepsin D | -0.0141353 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0140507 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0140195 |
| RPS14 | ribosomal protein S14 | -0.0136846 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.013605 |
| CENPF | centromere protein F, 350/400kDa | -0.0135802 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0135697 |
| RPL32 | ribosomal protein L32 | -0.0135095 |
| DIAPH3 | diaphanous-related formin 3 | -0.0134876 |
| RPL18 | ribosomal protein L18 | -0.0132948 |
| RPS29 | ribosomal protein S29 | -0.0131769 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0131537 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0130791 |
| RPL11 | ribosomal protein L11 | -0.0130754 |
| IGF2 | insulin-like growth factor 2 | -0.0129875 |
| ADM | adrenomedullin | -0.0129763 |
| S100A9 | S100 calcium binding protein A9 | -0.0129293 |
| S100A10 | S100 calcium binding protein A10 | -0.0128679 |
| RPL37A | ribosomal protein L37a | -0.0127771 |
| RPL34 | ribosomal protein L34 | -0.0127762 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0126611 |
| TUBA1B | tubulin, alpha 1b | -0.0126576 |
