| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.200015 |
| NDRG1 | N-myc downstream regulated 1 | 0.185761 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.176552 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.166788 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.160341 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.10794 |
| VEGFA | vascular endothelial growth factor A | 0.0975551 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0824693 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0763529 |
| KRT18 | keratin 18, type I | 0.0744684 |
| PLEC | plectin | 0.071814 |
| FAT1 | FAT atypical cadherin 1 | 0.0707531 |
| KRT8 | keratin 8, type II | 0.0696093 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.067894 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0667895 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0647869 |
| RPL3 | ribosomal protein L3 | 0.0623999 |
| HELZ | helicase with zinc finger | 0.0612391 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0586466 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0575713 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0562821 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.053283 |
| EGR1 | early growth response 1 | 0.0503184 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.048278 |
| YEATS2 | YEATS domain containing 2 | 0.0478244 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0460142 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0454902 |
| NUP58 | nucleoporin 58 | 0.0449544 |
| FLNB | filamin B, beta | 0.044308 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0441096 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0438409 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.043531 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0422445 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0421779 |
| CTBP2 | C-terminal binding protein 2 | 0.0419121 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0415765 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0412879 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0407509 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0404087 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0403052 |
| MKI67 | marker of proliferation Ki-67 | 0.0400572 |
| HOXB9 | homeobox B9 | 0.039862 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0397628 |
| SETD5 | SET domain containing 5 | 0.0390706 |
| CDK19 | cyclin-dependent kinase 19 | 0.0385037 |
| BRD2 | bromodomain containing 2 | 0.0382165 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.037928 |
| MCL1 | myeloid cell leukemia 1 | 0.0376883 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0376215 |
| COPA | coatomer protein complex, subunit alpha | 0.0375684 |
| PRELID2 | PRELI domain containing 2 | 0.0373151 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0372791 |
| ZNF292 | zinc finger protein 292 | 0.0372376 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0367441 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0366531 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.03614 |
| DSPP | dentin sialophosphoprotein | 0.0356315 |
| MED15 | mediator complex subunit 15 | 0.0350764 |
| BBX | bobby sox homolog (Drosophila) | 0.0346462 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0346364 |
| CANX | calnexin | 0.0339701 |
| FLNA | filamin A, alpha | 0.0339045 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0337257 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.033449 |
| PKM | pyruvate kinase, muscle | 0.0333926 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0332947 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0327981 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0326781 |
| GOLGA4 | golgin A4 | 0.0325896 |
| NONO | non-POU domain containing, octamer-binding | 0.0325482 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0322351 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0322131 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0320665 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0320155 |
| CEP250 | centrosomal protein 250kDa | 0.0319916 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.03138 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0313187 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0312236 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0305989 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0304284 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0302906 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0302096 |
| PCBP2 | poly(rC) binding protein 2 | 0.0297517 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0296556 |
| RNF24 | ring finger protein 24 | 0.0296403 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0295712 |
| CALR | calreticulin | 0.0295029 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0294506 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0292957 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0289671 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0286924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0284243 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0283306 |
| TPM3 | tropomyosin 3 | 0.0280272 |
| PGK1 | phosphoglycerate kinase 1 | 0.0278715 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0276607 |
| RUNX1 | runt-related transcription factor 1 | 0.027483 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0274287 |
| HPCAL1 | hippocalcin-like 1 | 0.0273925 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0272005 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.221193 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108218 |
| AHNAK | AHNAK nucleoprotein | -0.105932 |
| TMSB10 | thymosin beta 10 | -0.0584984 |
| RPL35A | ribosomal protein L35a | -0.049057 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0484275 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452406 |
| RPS24 | ribosomal protein S24 | -0.0434597 |
| FTL | ferritin, light polypeptide | -0.041427 |
| RPL34 | ribosomal protein L34 | -0.040803 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036421 |
| RPS6 | ribosomal protein S6 | -0.0327523 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0318288 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0302708 |
| RPL4 | ribosomal protein L4 | -0.025923 |
| RPLP2 | ribosomal protein, large, P2 | -0.0249012 |
| CCDC47 | coiled-coil domain containing 47 | -0.0247042 |
| RPS8 | ribosomal protein S8 | -0.0237097 |
| JMJD1C | jumonji domain containing 1C | -0.0236072 |
| RPS27A | ribosomal protein S27a | -0.0235701 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0232426 |
| RPS20 | ribosomal protein S20 | -0.0227399 |
| CCND1 | cyclin D1 | -0.0222014 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0221983 |
| RPL12 | ribosomal protein L12 | -0.0219618 |
| RPS16 | ribosomal protein S16 | -0.0214423 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0213131 |
| R3HDM1 | R3H domain containing 1 | -0.0212545 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0206501 |
| RPS5 | ribosomal protein S5 | -0.020625 |
| RPL27A | ribosomal protein L27a | -0.0200473 |
| RPL28 | ribosomal protein L28 | -0.0197746 |
| RTN3 | reticulon 3 | -0.0194395 |
| RPS19 | ribosomal protein S19 | -0.0192855 |
| EPCAM | epithelial cell adhesion molecule | -0.0187423 |
| HMGB1 | high mobility group box 1 | -0.01865 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0186035 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0184891 |
| RPS25 | ribosomal protein S25 | -0.0182367 |
| RPL26 | ribosomal protein L26 | -0.0182345 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0180532 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0180386 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.017859 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0175584 |
| RPL31 | ribosomal protein L31 | -0.017545 |
| RPS2 | ribosomal protein S2 | -0.0173592 |
| RPL38 | ribosomal protein L38 | -0.0170585 |
| TENM3 | teneurin transmembrane protein 3 | -0.016835 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0167581 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0166228 |
| RPL37 | ribosomal protein L37 | -0.016586 |
| GPHN | gephyrin | -0.0164611 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0164596 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0162346 |
| RPL32 | ribosomal protein L32 | -0.0162069 |
| RPS28 | ribosomal protein S28 | -0.0160282 |
| LRRC23 | leucine rich repeat containing 23 | -0.0160019 |
| S100A10 | S100 calcium binding protein A10 | -0.0159623 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0158998 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0158776 |
| KLHDC10 | kelch domain containing 10 | -0.0158692 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.015761 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0156551 |
| CDK13 | cyclin-dependent kinase 13 | -0.0156424 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0156228 |
| RPL19 | ribosomal protein L19 | -0.015543 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0152682 |
| RPS29 | ribosomal protein S29 | -0.0152345 |
| NFIA | nuclear factor I/A | -0.0151321 |
| UBB | ubiquitin B | -0.0148856 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0147533 |
| MTDH | metadherin | -0.0147296 |
| FRMD5 | FERM domain containing 5 | -0.0147154 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0146245 |
| RPL14 | ribosomal protein L14 | -0.014551 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.014376 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0142614 |
| RPL39 | ribosomal protein L39 | -0.0142343 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.014067 |
| RANBP17 | RAN binding protein 17 | -0.0140068 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.01384 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0138126 |
| SRSF10 | serine/arginine-rich splicing factor 10 | -0.013746 |
| TUT4 | terminal uridylyl transferase 4 | -0.0136509 |
| NOP58 | NOP58 ribonucleoprotein | -0.0136393 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0134882 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0134142 |
| RPS13 | ribosomal protein S13 | -0.0133659 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0133329 |
| IER3 | immediate early response 3 | -0.0133027 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0132999 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0132352 |
| EVI5 | ecotropic viral integration site 5 | -0.0131387 |
| SCFD2 | sec1 family domain containing 2 | -0.0130947 |
| RPS15 | ribosomal protein S15 | -0.0129907 |
| EREG | epiregulin | -0.0128876 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0128373 |
| ABLIM1 | actin binding LIM protein 1 | -0.0127378 |
| RPL36 | ribosomal protein L36 | -0.0126092 |
| TMEM123 | transmembrane protein 123 | -0.0125963 |
