| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cyclosporin A_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.203016 |
| PLEC | plectin | 0.129206 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.119131 |
| FLNA | filamin A, alpha | 0.114629 |
| APP | amyloid beta (A4) precursor protein | 0.100985 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0979712 |
| FLNB | filamin B, beta | 0.0855764 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0709689 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0686548 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0654472 |
| SMAD3 | SMAD family member 3 | 0.0644985 |
| FNDC3B | fibronectin type III domain containing 3B | 0.063344 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0633079 |
| CALR | calreticulin | 0.0604874 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0577919 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0573071 |
| SEPTIN9 | septin 9 | 0.0540856 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.050594 |
| RPL3 | ribosomal protein L3 | 0.0490706 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0487331 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0486895 |
| SETD5 | SET domain containing 5 | 0.0485924 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0479777 |
| LAMC2 | laminin, gamma 2 | 0.0476239 |
| ASPH | aspartate beta-hydroxylase | 0.0461234 |
| VEGFA | vascular endothelial growth factor A | 0.0459883 |
| KRT7 | keratin 7, type II | 0.0456211 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.044911 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0447175 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0444064 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0442295 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0429237 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0422737 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0409069 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0405768 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0402612 |
| PAX8 | paired box 8 | 0.0397162 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0396953 |
| MED15 | mediator complex subunit 15 | 0.0393983 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0387094 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.037498 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0371721 |
| LAMB3 | laminin, beta 3 | 0.0366393 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0363781 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0363073 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0362857 |
| PRELID2 | PRELI domain containing 2 | 0.0361977 |
| SET | SET nuclear proto-oncogene | 0.0358695 |
| PATJ | PATJ crumbs cell polarity complex component | 0.035604 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0355225 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0353771 |
| CANX | calnexin | 0.0351374 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0345149 |
| MINK1 | misshapen-like kinase 1 | 0.0340317 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0338115 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0330653 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0327601 |
| PTK2 | protein tyrosine kinase 2 | 0.0325113 |
| AFDN | afadin, adherens junction formation factor | 0.0324867 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0323485 |
| CLTC | clathrin, heavy chain (Hc) | 0.0321984 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.03145 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0312425 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0311305 |
| UPP1 | uridine phosphorylase 1 | 0.0308018 |
| B2M | beta-2-microglobulin | 0.0305497 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0303858 |
| MKI67 | marker of proliferation Ki-67 | 0.0303387 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0300934 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.029808 |
| ATXN1 | ataxin 1 | 0.0296943 |
| TPM3 | tropomyosin 3 | 0.0294534 |
| GSK3B | glycogen synthase kinase 3 beta | 0.029434 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0293574 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0293105 |
| RNF213 | ring finger protein 213 | 0.0291238 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0290578 |
| CD44 | CD44 molecule (Indian blood group) | 0.0290287 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.028639 |
| POTEF | POTE ankyrin domain family, member F | 0.0283278 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.028196 |
| COPA | coatomer protein complex, subunit alpha | 0.0278564 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0274864 |
| ATXN2 | ataxin 2 | 0.0274838 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0273205 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0272863 |
| FNIP1 | folliculin interacting protein 1 | 0.027134 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0268797 |
| CTBP2 | C-terminal binding protein 2 | 0.0268134 |
| BCL2L1 | BCL2-like 1 | 0.0266679 |
| ZFHX3 | zinc finger homeobox 3 | 0.0266585 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0266288 |
| PRRC2C | proline-rich coiled-coil 2C | 0.026436 |
| ACTN1 | actinin, alpha 1 | 0.0262083 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0258925 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0257976 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0256608 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.025513 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0253172 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0248903 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150843 |
| FTL | ferritin, light polypeptide | -0.11717 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.116657 |
| TMSB10 | thymosin beta 10 | -0.116412 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.102854 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0856539 |
| RPL35A | ribosomal protein L35a | -0.073931 |
| CCND1 | cyclin D1 | -0.067244 |
| RPS6 | ribosomal protein S6 | -0.0634253 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0482554 |
| PTMA | prothymosin, alpha | -0.0462601 |
| RPS24 | ribosomal protein S24 | -0.0447649 |
| RPL19 | ribosomal protein L19 | -0.0447644 |
| RPLP1 | ribosomal protein, large, P1 | -0.044584 |
| RPL23 | ribosomal protein L23 | -0.0421055 |
| RPS8 | ribosomal protein S8 | -0.0419244 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0410399 |
| ENO1 | enolase 1, (alpha) | -0.0403648 |
| HMGB1 | high mobility group box 1 | -0.0398468 |
| RPL12 | ribosomal protein L12 | -0.0395923 |
| RPS19 | ribosomal protein S19 | -0.037909 |
| AHNAK | AHNAK nucleoprotein | -0.0376514 |
| LDHA | lactate dehydrogenase A | -0.0360512 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0348734 |
| RPL28 | ribosomal protein L28 | -0.0342925 |
| IER3 | immediate early response 3 | -0.0332335 |
| RPL32 | ribosomal protein L32 | -0.0329115 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0326226 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0321551 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0318994 |
| RPS14 | ribosomal protein S14 | -0.0316289 |
| GNAS | GNAS complex locus | -0.0309444 |
| RPLP2 | ribosomal protein, large, P2 | -0.0308157 |
| RPL38 | ribosomal protein L38 | -0.0294907 |
| S100A10 | S100 calcium binding protein A10 | -0.0292922 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.028562 |
| RPL26 | ribosomal protein L26 | -0.0285369 |
| MACROD2 | MACRO domain containing 2 | -0.028509 |
| HMGA1 | high mobility group AT-hook 1 | -0.0284887 |
| RPS15 | ribosomal protein S15 | -0.0279562 |
| S100A9 | S100 calcium binding protein A9 | -0.0278193 |
| RPL37A | ribosomal protein L37a | -0.0275905 |
| RPL31 | ribosomal protein L31 | -0.0273793 |
| RPL34 | ribosomal protein L34 | -0.0273195 |
| RPS16 | ribosomal protein S16 | -0.0268482 |
| RPS29 | ribosomal protein S29 | -0.0263387 |
| RPL13A | ribosomal protein L13a | -0.0262526 |
| RPL9 | ribosomal protein L9 | -0.0261808 |
| NPR2 | natriuretic peptide receptor 2 | -0.0257134 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0254038 |
| RPL27 | ribosomal protein L27 | -0.0251002 |
| RPL4 | ribosomal protein L4 | -0.0244184 |
| RPS5 | ribosomal protein S5 | -0.0239532 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0238526 |
| RPL35 | ribosomal protein L35 | -0.0233636 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0227459 |
| RPL11 | ribosomal protein L11 | -0.0225278 |
| RPS21 | ribosomal protein S21 | -0.0220912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0220001 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.021872 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0218671 |
| S100A6 | S100 calcium binding protein A6 | -0.0218481 |
| RPL5 | ribosomal protein L5 | -0.0218138 |
| WWOX | WW domain containing oxidoreductase | -0.021795 |
| RPS20 | ribosomal protein S20 | -0.0215754 |
| RPS27A | ribosomal protein S27a | -0.0213808 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0213008 |
| RPS25 | ribosomal protein S25 | -0.0207158 |
| LDHB | lactate dehydrogenase B | -0.020629 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0206162 |
| ITGB8 | integrin, beta 8 | -0.0205757 |
| DSTN | destrin (actin depolymerizing factor) | -0.0205194 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0203766 |
| DEK | DEK proto-oncogene | -0.0203107 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0200919 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0198428 |
| FAM162A | family with sequence similarity 162, member A | -0.019735 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0196827 |
| RPS4X | ribosomal protein S4, X-linked | -0.019527 |
| TFRC | transferrin receptor | -0.0193055 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0191395 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0191129 |
| WWC1 | WW and C2 domain containing 1 | -0.0189986 |
| RPL36 | ribosomal protein L36 | -0.0189693 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0188552 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0187396 |
| MATR3 | matrin 3 | -0.0186275 |
| RPS11 | ribosomal protein S11 | -0.0185304 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0184828 |
| RPS3 | ribosomal protein S3 | -0.0183796 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0182487 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0181417 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0181284 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0181024 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0178409 |
| RPS23 | ribosomal protein S23 | -0.0176204 |
| RPS2 | ribosomal protein S2 | -0.0174866 |
| RPL27A | ribosomal protein L27a | -0.0174269 |
| SFXN1 | sideroflexin 1 | -0.0171477 |
| RTN4 | reticulon 4 | -0.0171273 |
