| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.121968 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0987356 |
| FAM13A | family with sequence similarity 13, member A | 0.0853458 |
| VEGFA | vascular endothelial growth factor A | 0.0846142 |
| PLEC | plectin | 0.0720629 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0698366 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0697676 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0654134 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0563011 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0541839 |
| YBX1 | Y box binding protein 1 | 0.0537307 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0493526 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0468256 |
| G0S2 | G0/G1 switch 2 | 0.0446785 |
| FLNB | filamin B, beta | 0.0425224 |
| ZNF292 | zinc finger protein 292 | 0.0392479 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.038445 |
| LOC112694756 | uncharaterized LOC112694756 | 0.037777 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0372924 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0372213 |
| FLNA | filamin A, alpha | 0.0366465 |
| CD44 | CD44 molecule (Indian blood group) | 0.0361506 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0359549 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0350053 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0345191 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0341593 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0337531 |
| PKM | pyruvate kinase, muscle | 0.0334348 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0332943 |
| RPL3 | ribosomal protein L3 | 0.032325 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0320471 |
| SMAD3 | SMAD family member 3 | 0.031197 |
| NUP58 | nucleoporin 58 | 0.0311312 |
| STC1 | stanniocalcin 1 | 0.0309315 |
| CDCP1 | CUB domain containing protein 1 | 0.0307632 |
| ARRDC3 | arrestin domain containing 3 | 0.0302039 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0297714 |
| FOSL1 | FOS-like antigen 1 | 0.0292549 |
| NONO | non-POU domain containing, octamer-binding | 0.0291817 |
| OGA | O-GlcNAcase | 0.0290083 |
| RACK1 | receptor for activated C kinase 1 | 0.0283168 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0273623 |
| CANX | calnexin | 0.0273588 |
| HELZ | helicase with zinc finger | 0.0271875 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.027146 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270034 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0259399 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.025518 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253354 |
| RNF145 | ring finger protein 145 | 0.0249638 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0246955 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.02468 |
| RPS12 | ribosomal protein S12 | 0.0246057 |
| NAV2 | neuron navigator 2 | 0.0243582 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0241487 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239205 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0237936 |
| SEPTIN9 | septin 9 | 0.0231455 |
| SPAG9 | sperm associated antigen 9 | 0.0229485 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0226603 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0222064 |
| RPL12 | ribosomal protein L12 | 0.0219098 |
| SMTN | smoothelin | 0.0218802 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0218299 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0218119 |
| MATR3 | matrin 3 | 0.0215876 |
| WDR45B | WD repeat domain 45B | 0.0213244 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0209065 |
| IRS2 | insulin receptor substrate 2 | 0.0208074 |
| SET | SET nuclear proto-oncogene | 0.0207049 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.020577 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0201639 |
| JUN | jun proto-oncogene | 0.0200753 |
| RPS8 | ribosomal protein S8 | 0.0198931 |
| CALR | calreticulin | 0.0198898 |
| PRRC2C | proline-rich coiled-coil 2C | 0.019879 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.019874 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0196264 |
| RPS10 | ribosomal protein S10 | 0.0191483 |
| RPL7 | ribosomal protein L7 | 0.0190554 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0190243 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.018981 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0189296 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.018863 |
| HMGB2 | high mobility group box 2 | 0.0186847 |
| COL6A3 | collagen, type VI, alpha 3 | 0.01868 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0186042 |
| RPL23 | ribosomal protein L23 | 0.0182164 |
| APP | amyloid beta (A4) precursor protein | 0.0182008 |
| RLF | rearranged L-myc fusion | 0.0181142 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0180389 |
| PTK2 | protein tyrosine kinase 2 | 0.0180164 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0179702 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0177983 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0177611 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0176541 |
| USP3 | ubiquitin specific peptidase 3 | 0.0173737 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0171597 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0171409 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0171177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.322893 |
| FN1 | fibronectin 1 | -0.215964 |
| HMGA2 | high mobility group AT-hook 2 | -0.144305 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.104249 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0983593 |
| CDH13 | cadherin 13 | -0.0864538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0847879 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0802316 |
| ASPH | aspartate beta-hydroxylase | -0.0758052 |
| RAI14 | retinoic acid induced 14 | -0.0730305 |
| LOX | lysyl oxidase | -0.0708702 |
| IGF2 | insulin-like growth factor 2 | -0.0649487 |
| TENM2 | teneurin transmembrane protein 2 | -0.0631564 |
| CCND1 | cyclin D1 | -0.0587735 |
| EGR1 | early growth response 1 | -0.0557735 |
| COL5A1 | collagen, type V, alpha 1 | -0.0532164 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0513791 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0512713 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0507208 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0497029 |
| GLIS3 | GLIS family zinc finger 3 | -0.0493352 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0485665 |
| VCL | vinculin | -0.0474208 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0473674 |
| COL1A1 | collagen, type I, alpha 1 | -0.0463136 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0457592 |
| MYO10 | myosin X | -0.0438173 |
| TMSB10 | thymosin beta 10 | -0.0425716 |
| NAV1 | neuron navigator 1 | -0.042442 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0416222 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0411162 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0365074 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.035924 |
| MT2A | metallothionein 2A | -0.0354929 |
| CAVIN1 | caveolae associated protein 1 | -0.0347532 |
| IL1B | interleukin 1, beta | -0.0344472 |
| DIAPH2 | diaphanous-related formin 2 | -0.0344071 |
| MCL1 | myeloid cell leukemia 1 | -0.0343432 |
| FMN1 | formin 1 | -0.0343418 |
| INHBA | inhibin, beta A | -0.0340934 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0338547 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0337332 |
| BPTF | bromodomain PHD finger transcription factor | -0.0332371 |
| IGF1R | insulin-like growth factor 1 receptor | -0.032455 |
| CLMP | CXADR-like membrane protein | -0.0320427 |
| MAP4 | microtubule-associated protein 4 | -0.0317695 |
| RPS24 | ribosomal protein S24 | -0.0317454 |
| HIP1 | huntingtin interacting protein 1 | -0.0313798 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0313223 |
| CLIC4 | chloride intracellular channel 4 | -0.0309102 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0302809 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0302662 |
| USP34 | ubiquitin specific peptidase 34 | -0.0301502 |
| TPM4 | tropomyosin 4 | -0.0300024 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0297783 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0297087 |
| GOLGB1 | golgin B1 | -0.0295208 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.028821 |
| RAD51B | RAD51 paralog B | -0.0285864 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0283704 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0270772 |
| GLG1 | golgi glycoprotein 1 | -0.0269762 |
| PCBP3 | poly(rC) binding protein 3 | -0.0269092 |
| EGFR | epidermal growth factor receptor | -0.0267578 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0263032 |
| INTS6 | integrator complex subunit 6 | -0.0262808 |
| TUBB6 | tubulin, beta 6 class V | -0.0261321 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0258941 |
| FRMD4A | FERM domain containing 4A | -0.0258602 |
| EHBP1 | EH domain binding protein 1 | -0.0257405 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0254125 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0250886 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0249283 |
| AHNAK | AHNAK nucleoprotein | -0.0248401 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0248083 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0245825 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0245404 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0244933 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0243207 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0242479 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0242168 |
| PRSS23 | protease, serine, 23 | -0.0242055 |
| TMEM263 | transmembrane protein 263 | -0.0241862 |
| SMYD3 | SET and MYND domain containing 3 | -0.0240111 |
| ARF4 | ADP-ribosylation factor 4 | -0.0238951 |
| DUSP6 | dual specificity phosphatase 6 | -0.0237259 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.023438 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0233893 |
| CUX1 | cut-like homeobox 1 | -0.0233282 |
| PTMA | prothymosin, alpha | -0.023066 |
| ZNF609 | zinc finger protein 609 | -0.0228714 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0224922 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0224349 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0223396 |
| ATXN1 | ataxin 1 | -0.0223368 |
| JMJD1C | jumonji domain containing 1C | -0.022219 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0221932 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.021864 |
| RRBP1 | ribosome binding protein 1 | -0.0217294 |
| TMEM165 | transmembrane protein 165 | -0.0216604 |
