| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.267275 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.177442 |
| VEGFA | vascular endothelial growth factor A | 0.142405 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.118197 |
| PLEC | plectin | 0.0792808 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0669093 |
| NDRG1 | N-myc downstream regulated 1 | 0.0611208 |
| CADM1 | cell adhesion molecule 1 | 0.0575912 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0549964 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0547802 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0527644 |
| ATP13A3 | ATPase type 13A3 | 0.0515631 |
| CDH13 | cadherin 13 | 0.0496783 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0494053 |
| NAV2 | neuron navigator 2 | 0.0489393 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0470137 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0456961 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0439311 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0432134 |
| APP | amyloid beta (A4) precursor protein | 0.0383864 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0383658 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0375748 |
| CALR | calreticulin | 0.0375153 |
| FLNA | filamin A, alpha | 0.0366799 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0363695 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0352895 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0344612 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0343376 |
| FMNL2 | formin-like 2 | 0.0326521 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321902 |
| ARRDC3 | arrestin domain containing 3 | 0.0315234 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0295742 |
| PTK2 | protein tyrosine kinase 2 | 0.0290836 |
| RPL3 | ribosomal protein L3 | 0.0288825 |
| CD44 | CD44 molecule (Indian blood group) | 0.0288179 |
| ZNF292 | zinc finger protein 292 | 0.0279919 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0275411 |
| RACK1 | receptor for activated C kinase 1 | 0.0264921 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0262872 |
| ANXA2 | annexin A2 | 0.0261615 |
| SMAD3 | SMAD family member 3 | 0.025716 |
| ICAM1 | intercellular adhesion molecule 1 | 0.025467 |
| QKI | QKI, KH domain containing, RNA binding | 0.025288 |
| PDE10A | phosphodiesterase 10A | 0.0252124 |
| RASA2 | RAS p21 protein activator 2 | 0.0251032 |
| MED15 | mediator complex subunit 15 | 0.0242567 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.023857 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0230293 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0229019 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0225832 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0223242 |
| TFG | TRK-fused gene | 0.0222609 |
| CANX | calnexin | 0.022253 |
| RND3 | Rho family GTPase 3 | 0.0215323 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0214293 |
| TNS1 | tensin 1 | 0.0211714 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0209726 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0208609 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0205874 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0204053 |
| MRTFA | myocardin related transcription factor A | 0.0202101 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0201888 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0201817 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0201721 |
| PTMA | prothymosin, alpha | 0.0201715 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0196994 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0196438 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0196028 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0195278 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0192033 |
| YBX1 | Y box binding protein 1 | 0.0190444 |
| COL5A1 | collagen, type V, alpha 1 | 0.0189894 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0189276 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0178757 |
| FLNB | filamin B, beta | 0.0177461 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0177179 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0176499 |
| CCNY | cyclin Y | 0.0175786 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0175363 |
| STK10 | serine/threonine kinase 10 | 0.0175245 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0174104 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0173838 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0173779 |
| COPA | coatomer protein complex, subunit alpha | 0.0173505 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0170032 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0169592 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0168286 |
| TRAM2 | translocation associated membrane protein 2 | 0.0166772 |
| FAT1 | FAT atypical cadherin 1 | 0.0162072 |
| HMGB2 | high mobility group box 2 | 0.0160761 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0160005 |
| IL6ST | interleukin 6 signal transducer | 0.0159676 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0158871 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0157732 |
| DENND5A | DENN/MADD domain containing 5A | 0.0157549 |
| WTAP | Wilms tumor 1 associated protein | 0.0157421 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0156924 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0154194 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0154019 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0153134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.166032 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.153362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130909 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.124611 |
| MT2A | metallothionein 2A | -0.122833 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0983014 |
| COL1A1 | collagen, type I, alpha 1 | -0.092918 |
| COL1A2 | collagen, type I, alpha 2 | -0.0819488 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0703383 |
| LOX | lysyl oxidase | -0.0623772 |
| TPM4 | tropomyosin 4 | -0.0573515 |
| TMSB10 | thymosin beta 10 | -0.0481621 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0461683 |
| MAP1B | microtubule-associated protein 1B | -0.0422432 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0408918 |
| LDHA | lactate dehydrogenase A | -0.0372952 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0363023 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0354035 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0322358 |
| FTL | ferritin, light polypeptide | -0.0311528 |
| TAPBP | TAP binding protein (tapasin) | -0.0300277 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0294566 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.028561 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.028069 |
| POSTN | periostin, osteoblast specific factor | -0.0274214 |
| MYADM | myeloid-associated differentiation marker | -0.0253039 |
| FBN1 | fibrillin 1 | -0.0247274 |
| UBC | ubiquitin C | -0.0227744 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0225121 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0223583 |
| POTEF | POTE ankyrin domain family, member F | -0.0216185 |
| EGR1 | early growth response 1 | -0.021525 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0213235 |
| IER3 | immediate early response 3 | -0.0209919 |
| HLA-A | major histocompatibility complex, class I, A | -0.0207167 |
| ARF4 | ADP-ribosylation factor 4 | -0.0205452 |
| DSTN | destrin (actin depolymerizing factor) | -0.0192444 |
| VCAN | versican | -0.0187621 |
| AXL | AXL receptor tyrosine kinase | -0.0187613 |
| ECE1 | endothelin converting enzyme 1 | -0.018548 |
| BSG | basigin (Ok blood group) | -0.018508 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0178676 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0178442 |
| GOLGB1 | golgin B1 | -0.0177146 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0176599 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0173531 |
| GLIS3 | GLIS family zinc finger 3 | -0.0171553 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0169208 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0168622 |
| FN1 | fibronectin 1 | -0.0167133 |
| PFN1 | profilin 1 | -0.0164821 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0156165 |
| WASF2 | WAS protein family, member 2 | -0.0154294 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0154035 |
| IL6 | interleukin 6 | -0.0149336 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0148149 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0146857 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.014322 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0142777 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0141965 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0141741 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0139587 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0133615 |
| RTN4 | reticulon 4 | -0.0132442 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0132124 |
| MT1X | metallothionein 1X | -0.0131838 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0128332 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0127612 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0123849 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0123562 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0123212 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0123115 |
| TUBA1B | tubulin, alpha 1b | -0.0122921 |
| SEC24A | SEC24 family member A | -0.0121995 |
| S100A6 | S100 calcium binding protein A6 | -0.0121971 |
| RPS19 | ribosomal protein S19 | -0.0120585 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0119798 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0118958 |
| SCFD2 | sec1 family domain containing 2 | -0.0118221 |
| RPL27A | ribosomal protein L27a | -0.0117803 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0116928 |
| RPLP2 | ribosomal protein, large, P2 | -0.0115124 |
| RPS16 | ribosomal protein S16 | -0.0114446 |
| COL3A1 | collagen, type III, alpha 1 | -0.0114442 |
| RPLP1 | ribosomal protein, large, P1 | -0.0113765 |
| PKM | pyruvate kinase, muscle | -0.0113068 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0112678 |
| EGFR | epidermal growth factor receptor | -0.0112167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0108534 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0108166 |
| CCND1 | cyclin D1 | -0.0107071 |
| NRP1 | neuropilin 1 | -0.0106259 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0106187 |
| RPS14 | ribosomal protein S14 | -0.0104586 |
| YIPF5 | Yip1 domain family, member 5 | -0.0104194 |
| CTSD | cathepsin D | -0.0103573 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0103467 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0102389 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0101734 |
| PERP | PERP, TP53 apoptosis effector | -0.0100969 |
