| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.111503 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0926596 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0912906 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0860257 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.06896 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0613494 |
| FBXO32 | F-box protein 32 | 0.0553101 |
| OGA | O-GlcNAcase | 0.0523487 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.051791 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0498815 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0482389 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0481329 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0478438 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0463369 |
| PLEC | plectin | 0.0452779 |
| HYOU1 | hypoxia up-regulated 1 | 0.0446209 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0440934 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0439304 |
| KRT8 | keratin 8, type II | 0.0439187 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0431535 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0424889 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0422242 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0416424 |
| LOC112694756 | uncharaterized LOC112694756 | 0.040675 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0402658 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0401731 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0384306 |
| BRD2 | bromodomain containing 2 | 0.0381647 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0380237 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.036325 |
| YBX1 | Y box binding protein 1 | 0.0350421 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0347444 |
| SUCO | SUN domain containing ossification factor | 0.0336985 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0335618 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0333734 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0327397 |
| PDZD8 | PDZ domain containing 8 | 0.0325518 |
| VEGFA | vascular endothelial growth factor A | 0.0325415 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0323556 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0322909 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0317106 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0313598 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0306983 |
| TUFT1 | tuftelin 1 | 0.0300134 |
| SMAD3 | SMAD family member 3 | 0.0298755 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0298407 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0295002 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0292109 |
| HELZ | helicase with zinc finger | 0.0290922 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0289699 |
| ANLN | anillin, actin binding protein | 0.0287504 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0286532 |
| MED15 | mediator complex subunit 15 | 0.0286174 |
| LMO7 | LIM domain 7 | 0.0284142 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0283921 |
| KRT18 | keratin 18, type I | 0.0282625 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0281185 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0279845 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275279 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0274221 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0273921 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0273784 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0272788 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0271836 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.027086 |
| PGM3 | phosphoglucomutase 3 | 0.0270513 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0269909 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0269596 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.026905 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0267532 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0266679 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0265981 |
| NUP58 | nucleoporin 58 | 0.0265069 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.026482 |
| FAT1 | FAT atypical cadherin 1 | 0.0264654 |
| CUL3 | cullin 3 | 0.0262895 |
| CALU | calumenin | 0.0262891 |
| HMGB2 | high mobility group box 2 | 0.0262626 |
| AFF1 | AF4/FMR2 family, member 1 | 0.026035 |
| CANX | calnexin | 0.0259058 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0258817 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.025782 |
| RND3 | Rho family GTPase 3 | 0.025648 |
| RBM39 | RNA binding motif protein 39 | 0.0256477 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0256114 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0253481 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0252311 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0251424 |
| TOP1 | topoisomerase (DNA) I | 0.0244533 |
| SLMAP | sarcolemma associated protein | 0.0244213 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0242841 |
| FLNA | filamin A, alpha | 0.0242641 |
| RPLP0 | ribosomal protein, large, P0 | 0.0242415 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0241167 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0240543 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0240128 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0240046 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0239027 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0238984 |
| HOXB9 | homeobox B9 | 0.0237879 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | -0.116604 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.102756 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.101749 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0943885 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0872788 |
| FRY | furry homolog (Drosophila) | -0.0853856 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0805049 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0788134 |
| TMSB10 | thymosin beta 10 | -0.0781888 |
| PTMA | prothymosin, alpha | -0.07582 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0739237 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0704129 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0702745 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.069441 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.065137 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0644334 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0634588 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0633034 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0608731 |
| DGKH | diacylglycerol kinase, eta | -0.0602719 |
| DIAPH2 | diaphanous-related formin 2 | -0.0593449 |
| RPS6 | ribosomal protein S6 | -0.0592673 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0592304 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0586027 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0577659 |
| LYZ | lysozyme | -0.0561202 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0547148 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0546915 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0540469 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0526377 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0504875 |
| ANXA2 | annexin A2 | -0.0504594 |
| KRT20 | keratin 20, type I | -0.0503629 |
| WASF2 | WAS protein family, member 2 | -0.0498302 |
| LAMA4 | laminin, alpha 4 | -0.0495176 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0490159 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0448433 |
| TMC5 | transmembrane channel-like 5 | -0.0437514 |
| S100A6 | S100 calcium binding protein A6 | -0.0434886 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0431376 |
| FTL | ferritin, light polypeptide | -0.0430711 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0412546 |
| TMEM123 | transmembrane protein 123 | -0.0411727 |
| RNF213 | ring finger protein 213 | -0.0408652 |
| EXOC4 | exocyst complex component 4 | -0.0406026 |
| PCED1B | PC-esterase domain containing 1B | -0.0397994 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0396172 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0375661 |
| POF1B | premature ovarian failure, 1B | -0.0374339 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.037422 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0367159 |
| CA12 | carbonic anhydrase XII | -0.0366411 |
| ETV6 | ets variant 6 | -0.0350285 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0349308 |
| ACACA | acetyl-CoA carboxylase alpha | -0.034683 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0340911 |
| KLK10 | kallikrein-related peptidase 10 | -0.0337384 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0329026 |
| MUC13 | mucin 13, cell surface associated | -0.0328016 |
| MMP7 | matrix metallopeptidase 7 | -0.0325248 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0320629 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0315388 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0314257 |
| KLF10 | Kruppel-like factor 10 | -0.0314214 |
| KRT19 | keratin 19, type I | -0.0313164 |
| FOXP1 | forkhead box P1 | -0.0308893 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0305377 |
| PGK1 | phosphoglycerate kinase 1 | -0.0304879 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0304357 |
| JUP | junction plakoglobin | -0.030266 |
| JUN | jun proto-oncogene | -0.0294472 |
| MECOM | MDS1 and EVI1 complex locus | -0.0292173 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.02902 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0289601 |
| ITGA1 | integrin, alpha 1 | -0.0285486 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0283536 |
| POTEF | POTE ankyrin domain family, member F | -0.0283535 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0282157 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0280965 |
| TCF12 | transcription factor 12 | -0.0280834 |
| PKM | pyruvate kinase, muscle | -0.0276476 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0274311 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0267621 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0266879 |
| AHNAK | AHNAK nucleoprotein | -0.0266005 |
| RRBP1 | ribosome binding protein 1 | -0.0264113 |
| CCDC91 | coiled-coil domain containing 91 | -0.0259001 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0258936 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0257388 |
| BPTF | bromodomain PHD finger transcription factor | -0.0255117 |
| PRELID2 | PRELI domain containing 2 | -0.0254701 |
| USP54 | ubiquitin specific peptidase 54 | -0.0253979 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0253394 |
| EGR1 | early growth response 1 | -0.0251895 |
| AGR2 | anterior gradient 2 | -0.0250874 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0250016 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0249132 |
| CUX1 | cut-like homeobox 1 | -0.0248727 |
| GPX2 | glutathione peroxidase 2 | -0.0246937 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0245829 |
