| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.280635 |
| NDRG1 | N-myc downstream regulated 1 | 0.167413 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.167347 |
| PLEC | plectin | 0.152239 |
| PODXL | podocalyxin-like | 0.132648 |
| MSN | moesin | 0.115236 |
| KRT6A | keratin 6A, type II | 0.0885166 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0830399 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0805276 |
| MTSS1 | metastasis suppressor 1 | 0.0789555 |
| FLNA | filamin A, alpha | 0.0688449 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.06589 |
| CD44 | CD44 molecule (Indian blood group) | 0.0648823 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0634893 |
| ITGA6 | integrin, alpha 6 | 0.0632841 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0599445 |
| GRB10 | growth factor receptor-bound protein 10 | 0.059594 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.058158 |
| TGM2 | transglutaminase 2 | 0.0544153 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0542745 |
| TPM3 | tropomyosin 3 | 0.0541769 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0536791 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0528882 |
| EFHD2 | EF-hand domain family, member D2 | 0.0526653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0500199 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0495644 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0487195 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0484784 |
| FOXO1 | forkhead box O1 | 0.048292 |
| COPA | coatomer protein complex, subunit alpha | 0.0468087 |
| IGF2 | insulin-like growth factor 2 | 0.0457633 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0456093 |
| LAMC2 | laminin, gamma 2 | 0.0453737 |
| LMO7 | LIM domain 7 | 0.0450043 |
| EGR1 | early growth response 1 | 0.0449678 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.044764 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0444476 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0436887 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0427456 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0423034 |
| LAMA5 | laminin, alpha 5 | 0.0419154 |
| ANXA1 | annexin A1 | 0.0409769 |
| MCL1 | myeloid cell leukemia 1 | 0.0408293 |
| MEF2A | myocyte enhancer factor 2A | 0.0404891 |
| AMOTL1 | angiomotin like 1 | 0.0402273 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0398572 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0394895 |
| CEP250 | centrosomal protein 250kDa | 0.0392848 |
| NAV2 | neuron navigator 2 | 0.0384322 |
| CUL4B | cullin 4B | 0.0383778 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0380705 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0380551 |
| PLS3 | plastin 3 | 0.0379764 |
| MED15 | mediator complex subunit 15 | 0.0377069 |
| VEGFA | vascular endothelial growth factor A | 0.0375564 |
| EZR | ezrin | 0.037231 |
| BCL2L1 | BCL2-like 1 | 0.0370947 |
| APP | amyloid beta (A4) precursor protein | 0.0365108 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0353802 |
| SMAD3 | SMAD family member 3 | 0.035087 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0350223 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0349966 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0348134 |
| MYO10 | myosin X | 0.0346351 |
| RPL3 | ribosomal protein L3 | 0.0340825 |
| RASAL2 | RAS protein activator like 2 | 0.0338764 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0333514 |
| ARRDC3 | arrestin domain containing 3 | 0.0332065 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0328424 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0325259 |
| MYOF | myoferlin | 0.0324448 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0322207 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0322082 |
| EPHA2 | EPH receptor A2 | 0.03195 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0318046 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0317905 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0317196 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0316223 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0315393 |
| BLCAP | bladder cancer associated protein | 0.0314907 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0312969 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0312174 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.031119 |
| YOD1 | YOD1 deubiquitinase | 0.0303608 |
| FOSL1 | FOS-like antigen 1 | 0.0298893 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0297829 |
| ANXA2 | annexin A2 | 0.0296495 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296419 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0289434 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0288886 |
| SEPTIN9 | septin 9 | 0.0287021 |
| SULF1 | sulfatase 1 | 0.0286606 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0285805 |
| B2M | beta-2-microglobulin | 0.0278086 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0275503 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0273422 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0272549 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0271372 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.026974 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0265649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.133753 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113318 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0845412 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0766519 |
| TMSB10 | thymosin beta 10 | -0.0730167 |
| RPLP1 | ribosomal protein, large, P1 | -0.0632378 |
| RPS6 | ribosomal protein S6 | -0.0612875 |
| RPS21 | ribosomal protein S21 | -0.0596151 |
| RPS24 | ribosomal protein S24 | -0.0491014 |
| GNAS | GNAS complex locus | -0.0478428 |
| MT2A | metallothionein 2A | -0.0465189 |
| RPLP2 | ribosomal protein, large, P2 | -0.0464122 |
| RPS8 | ribosomal protein S8 | -0.0443919 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0427438 |
| RPS19 | ribosomal protein S19 | -0.0385146 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0367469 |
| RPL34 | ribosomal protein L34 | -0.0363895 |
| AHNAK | AHNAK nucleoprotein | -0.0353085 |
| RPL35A | ribosomal protein L35a | -0.0341232 |
| RPL11 | ribosomal protein L11 | -0.0334217 |
| RPL27A | ribosomal protein L27a | -0.0325622 |
| RPL12 | ribosomal protein L12 | -0.03128 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307213 |
| PTMA | prothymosin, alpha | -0.0306539 |
| RPS25 | ribosomal protein S25 | -0.0305621 |
| S100A10 | S100 calcium binding protein A10 | -0.0303701 |
| S100A6 | S100 calcium binding protein A6 | -0.0292281 |
| FTL | ferritin, light polypeptide | -0.0291961 |
| RPL8 | ribosomal protein L8 | -0.0286348 |
| RPS20 | ribosomal protein S20 | -0.0284863 |
| RPL37 | ribosomal protein L37 | -0.0270471 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0268859 |
| RPS13 | ribosomal protein S13 | -0.0263236 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0262796 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0255918 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0252053 |
| S100A2 | S100 calcium binding protein A2 | -0.0249417 |
| RPL39 | ribosomal protein L39 | -0.0245751 |
| IER3 | immediate early response 3 | -0.0242817 |
| RPL23 | ribosomal protein L23 | -0.0239643 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0235858 |
| RPS14 | ribosomal protein S14 | -0.0233054 |
| RPL32 | ribosomal protein L32 | -0.0232472 |
| RPS27A | ribosomal protein S27a | -0.0230621 |
| HMGB1 | high mobility group box 1 | -0.0228537 |
| RPL19 | ribosomal protein L19 | -0.0226476 |
| RPS16 | ribosomal protein S16 | -0.0226203 |
| RPL5 | ribosomal protein L5 | -0.0223001 |
| RPL28 | ribosomal protein L28 | -0.0222821 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0222478 |
| ARF1 | ADP-ribosylation factor 1 | -0.022157 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0220534 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0218245 |
| RPL31 | ribosomal protein L31 | -0.0218097 |
| RPL26 | ribosomal protein L26 | -0.0209892 |
| RPS29 | ribosomal protein S29 | -0.0204143 |
| RPL35 | ribosomal protein L35 | -0.0199662 |
| RPS4X | ribosomal protein S4, X-linked | -0.019826 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0195596 |
| RPS5 | ribosomal protein S5 | -0.0194967 |
| TKT | transketolase | -0.0194893 |
| RPS11 | ribosomal protein S11 | -0.0192319 |
| RPL13A | ribosomal protein L13a | -0.019201 |
| RPL4 | ribosomal protein L4 | -0.0188532 |
| ADIRF | adipogenesis regulatory factor | -0.0184638 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0184621 |
| RPS2 | ribosomal protein S2 | -0.0182522 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0182044 |
| RPL7A | ribosomal protein L7a | -0.018199 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0180031 |
| RPL36 | ribosomal protein L36 | -0.0179337 |
| RPS23 | ribosomal protein S23 | -0.0178552 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0178247 |
| MT1X | metallothionein 1X | -0.0178021 |
| RPL30 | ribosomal protein L30 | -0.0174301 |
| DEK | DEK proto-oncogene | -0.0170492 |
| CAVIN1 | caveolae associated protein 1 | -0.0169974 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0169472 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0168128 |
| RPL37A | ribosomal protein L37a | -0.0164885 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.016466 |
| CSTB | cystatin B (stefin B) | -0.016396 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0162942 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0162736 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0162346 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0161007 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0159954 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0159312 |
| S100A4 | S100 calcium binding protein A4 | -0.0159126 |
| SEC61G | Sec61 gamma subunit | -0.0158237 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0157143 |
| RPL36A | ribosomal protein L36a | -0.0155973 |
| HMGA1 | high mobility group AT-hook 1 | -0.0153757 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0151852 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0151501 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0151182 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0150959 |
| RPLP0 | ribosomal protein, large, P0 | -0.0150923 |
| RPS15 | ribosomal protein S15 | -0.0150299 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0148162 |
