| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.075617 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0490225 |
| FLNB | filamin B, beta | 0.0468934 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0427406 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0412673 |
| ZNF841 | zinc finger protein 841 | 0.0386377 |
| NDRG1 | N-myc downstream regulated 1 | 0.0385486 |
| ATP13A3 | ATPase type 13A3 | 0.0374573 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0362426 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0356005 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0353275 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0350957 |
| VEGFA | vascular endothelial growth factor A | 0.0345221 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0296204 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0291184 |
| NAV2 | neuron navigator 2 | 0.028743 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0276511 |
| SMAD3 | SMAD family member 3 | 0.0271048 |
| PLEC | plectin | 0.0260332 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0252031 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0234809 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0220802 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0217831 |
| SPAG9 | sperm associated antigen 9 | 0.0214982 |
| FLNA | filamin A, alpha | 0.0213401 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0212063 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0204591 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0195351 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0185086 |
| AFAP1 | actin filament associated protein 1 | 0.0185067 |
| CEP250 | centrosomal protein 250kDa | 0.018064 |
| HLA-C | major histocompatibility complex, class I, C | 0.0175167 |
| ADM | adrenomedullin | 0.017224 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0171477 |
| IL6ST | interleukin 6 signal transducer | 0.0168476 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0164425 |
| NUP58 | nucleoporin 58 | 0.0163117 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0160692 |
| CD44 | CD44 molecule (Indian blood group) | 0.0160567 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.015844 |
| STK4 | serine/threonine kinase 4 | 0.0156964 |
| FMNL2 | formin-like 2 | 0.0155132 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0154647 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0152446 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0151503 |
| FUS | FUS RNA binding protein | 0.0150582 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.014939 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.014748 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0147209 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0146314 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0145981 |
| APP | amyloid beta (A4) precursor protein | 0.0144059 |
| PDE10A | phosphodiesterase 10A | 0.0142872 |
| OGA | O-GlcNAcase | 0.0142578 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0141936 |
| TPD52 | tumor protein D52 | 0.0141933 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0141307 |
| KLC1 | kinesin light chain 1 | 0.0140529 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0140449 |
| NONO | non-POU domain containing, octamer-binding | 0.0138879 |
| WTAP | Wilms tumor 1 associated protein | 0.0138519 |
| PLIN2 | perilipin 2 | 0.013761 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0136659 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.013641 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0135815 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0135543 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0134306 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0132346 |
| ARRDC3 | arrestin domain containing 3 | 0.0131649 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0131265 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0129854 |
| PTK2 | protein tyrosine kinase 2 | 0.0128891 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0127328 |
| ZFR | zinc finger RNA binding protein | 0.0125165 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0124222 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0124209 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.012315 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0123054 |
| FNIP1 | folliculin interacting protein 1 | 0.0121141 |
| PODXL | podocalyxin-like | 0.0120678 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.012018 |
| SFTPA2 | surfactant protein A2 | 0.0119394 |
| MKI67 | marker of proliferation Ki-67 | 0.0117799 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.011706 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0116923 |
| DENND5A | DENN/MADD domain containing 5A | 0.0116492 |
| NGLY1 | N-glycanase 1 | 0.0116313 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.011533 |
| UPP1 | uridine phosphorylase 1 | 0.0115266 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0115233 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.011422 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0113911 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0113872 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0113448 |
| FAM107B | family with sequence similarity 107, member B | 0.0112523 |
| AFDN | afadin, adherens junction formation factor | 0.0109108 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0109053 |
| DENND4C | DENN/MADD domain containing 4C | 0.0108859 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0108825 |
| DST | dystonin | 0.0107974 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.128461 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.108222 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0855608 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0667756 |
| POTEF | POTE ankyrin domain family, member F | -0.0599531 |
| MT2A | metallothionein 2A | -0.0472661 |
| DEK | DEK proto-oncogene | -0.0447273 |
| FN1 | fibronectin 1 | -0.0429695 |
| FTL | ferritin, light polypeptide | -0.041666 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0403789 |
| TMSB10 | thymosin beta 10 | -0.0291466 |
| LDHA | lactate dehydrogenase A | -0.0289934 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0284326 |
| ARF4 | ADP-ribosylation factor 4 | -0.0282961 |
| VIM | vimentin | -0.0267934 |
| TPM1 | tropomyosin 1 (alpha) | -0.0266343 |
| ERBIN | erbb2 interacting protein | -0.0250592 |
| ENO1 | enolase 1, (alpha) | -0.025053 |
| PFN1 | profilin 1 | -0.0246927 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0246259 |
| PKM | pyruvate kinase, muscle | -0.0240498 |
| RPS6 | ribosomal protein S6 | -0.0240151 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.02202 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0208585 |
| GLIS3 | GLIS family zinc finger 3 | -0.0205593 |
| CTSD | cathepsin D | -0.0200056 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0196411 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0193553 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0187827 |
| DIAPH3 | diaphanous-related formin 3 | -0.0186104 |
| ACTG1 | actin gamma 1 | -0.0185154 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.018272 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.017691 |
| MAP1B | microtubule-associated protein 1B | -0.0176402 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0174653 |
| SCFD2 | sec1 family domain containing 2 | -0.0173964 |
| ZNF804A | zinc finger protein 804A | -0.0173866 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0173783 |
| PLCB4 | phospholipase C, beta 4 | -0.0172945 |
| KRT7 | keratin 7, type II | -0.0172126 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.017073 |
| TPI1 | triosephosphate isomerase 1 | -0.0164852 |
| PCBP2 | poly(rC) binding protein 2 | -0.0164642 |
| TGFB2 | transforming growth factor, beta 2 | -0.0163234 |
| TENM3 | teneurin transmembrane protein 3 | -0.0162211 |
| HLA-A | major histocompatibility complex, class I, A | -0.0158117 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0156727 |
| VEGFC | vascular endothelial growth factor C | -0.0154397 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0154081 |
| CCND1 | cyclin D1 | -0.0149597 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0149315 |
| CCDC80 | coiled-coil domain containing 80 | -0.0148373 |
| SULF1 | sulfatase 1 | -0.0145983 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0144134 |
| LOX | lysyl oxidase | -0.0140934 |
| HMGB1 | high mobility group box 1 | -0.0139368 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0138246 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0137311 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0136954 |
| TPM4 | tropomyosin 4 | -0.0136147 |
| TUBA1B | tubulin, alpha 1b | -0.0135749 |
| TXNRD1 | thioredoxin reductase 1 | -0.0134941 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0134132 |
| CENPF | centromere protein F, 350/400kDa | -0.0131387 |
| S100A6 | S100 calcium binding protein A6 | -0.0128757 |
| EGR1 | early growth response 1 | -0.0128657 |
| RPLP2 | ribosomal protein, large, P2 | -0.0128286 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0127658 |
| TUBB | tubulin, beta class I | -0.0127438 |
| NRXN3 | neurexin 3 | -0.0126968 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0126872 |
| HMGA1 | high mobility group AT-hook 1 | -0.0126563 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0124131 |
| TAPBP | TAP binding protein (tapasin) | -0.0122304 |
| CALD1 | caldesmon 1 | -0.0122151 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0121987 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0118646 |
| LIMA1 | LIM domain and actin binding 1 | -0.0118279 |
| AXL | AXL receptor tyrosine kinase | -0.0117944 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0117553 |
| MYADM | myeloid-associated differentiation marker | -0.0117308 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0117305 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0116725 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0115692 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0114778 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0114622 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0113847 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0113831 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0113636 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.011362 |
| COG6 | component of oligomeric golgi complex 6 | -0.0112991 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0112709 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0111872 |
| TPX2 | TPX2, microtubule-associated | -0.0110731 |
| VCL | vinculin | -0.0109516 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0108676 |
| POSTN | periostin, osteoblast specific factor | -0.0108278 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.010782 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0107108 |
| HLA-B | major histocompatibility complex, class I, B | -0.0107076 |
