| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.226478 |
| VEGFA | vascular endothelial growth factor A | 0.113189 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0903144 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0864796 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0791616 |
| PLEC | plectin | 0.066461 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0650836 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0630103 |
| HYOU1 | hypoxia up-regulated 1 | 0.0626529 |
| NPSR1 | neuropeptide S receptor 1 | 0.0625739 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0622647 |
| FLNB | filamin B, beta | 0.0622288 |
| KRT18 | keratin 18, type I | 0.0520408 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0474458 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0473553 |
| LMO7 | LIM domain 7 | 0.0472299 |
| NCOR2 | nuclear receptor corepressor 2 | 0.047022 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0446813 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0444324 |
| ANXA1 | annexin A1 | 0.0441549 |
| KLHL29 | kelch-like family member 29 | 0.0440989 |
| NDRG1 | N-myc downstream regulated 1 | 0.0431189 |
| GOLGA4 | golgin A4 | 0.0406316 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0404132 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0390151 |
| PGM3 | phosphoglucomutase 3 | 0.0368197 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0363766 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0354793 |
| MYO5B | myosin VB | 0.0351952 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0344504 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0334777 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0322428 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0319255 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0318798 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0314602 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0299654 |
| ANXA2 | annexin A2 | 0.0291749 |
| HKDC1 | hexokinase domain containing 1 | 0.0285553 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0278191 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273874 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0273399 |
| HM13 | histocompatibility (minor) 13 | 0.0273023 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0269791 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268703 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0263627 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0262768 |
| ANXA3 | annexin A3 | 0.0262442 |
| KIF16B | kinesin family member 16B | 0.0261866 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0261286 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0260702 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0259488 |
| RPL3 | ribosomal protein L3 | 0.025193 |
| H1-0 | H1.0 linker histone | 0.0251167 |
| DSPP | dentin sialophosphoprotein | 0.0249992 |
| TPM3 | tropomyosin 3 | 0.0249368 |
| NONO | non-POU domain containing, octamer-binding | 0.0248098 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.024797 |
| MYO18A | myosin XVIIIA | 0.0247719 |
| KRT7 | keratin 7, type II | 0.0244523 |
| FAM13A | family with sequence similarity 13, member A | 0.0244279 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0242969 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0242853 |
| COPA | coatomer protein complex, subunit alpha | 0.0241837 |
| SET | SET nuclear proto-oncogene | 0.0240602 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0240201 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0238697 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0238607 |
| HDAC9 | histone deacetylase 9 | 0.0237538 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0235825 |
| LAMB3 | laminin, beta 3 | 0.0235174 |
| KRT8 | keratin 8, type II | 0.0234166 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0230627 |
| GOLGB1 | golgin B1 | 0.023024 |
| FNIP1 | folliculin interacting protein 1 | 0.0229451 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0229095 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0228684 |
| BRD2 | bromodomain containing 2 | 0.0227137 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0226856 |
| KRT17 | keratin 17, type I | 0.0226559 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0226431 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 0.0223691 |
| PRDM16 | PR domain containing 16 | 0.022046 |
| ITGA6 | integrin, alpha 6 | 0.0218498 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0217385 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0216014 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0215342 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0212267 |
| HELZ | helicase with zinc finger | 0.0211981 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0209424 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.020888 |
| DSCAM | Down syndrome cell adhesion molecule | 0.020881 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0207456 |
| TRIM2 | tripartite motif containing 2 | 0.0206687 |
| PMM2 | phosphomannomutase 2 | 0.0205571 |
| FLNA | filamin A, alpha | 0.0205324 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0203103 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0202452 |
| RNF213 | ring finger protein 213 | 0.0200527 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0200064 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0199896 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.168822 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.132192 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115164 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0990343 |
| RPL35A | ribosomal protein L35a | -0.0973603 |
| RPLP1 | ribosomal protein, large, P1 | -0.0852763 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0837167 |
| FTL | ferritin, light polypeptide | -0.0787209 |
| RPS19 | ribosomal protein S19 | -0.0747603 |
| RPS6 | ribosomal protein S6 | -0.0678402 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0639957 |
| PTMA | prothymosin, alpha | -0.061634 |
| RPL23 | ribosomal protein L23 | -0.0561728 |
| RPS24 | ribosomal protein S24 | -0.054779 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.053489 |
| S100A9 | S100 calcium binding protein A9 | -0.0534661 |
| RPS25 | ribosomal protein S25 | -0.0524361 |
| RPS21 | ribosomal protein S21 | -0.0485544 |
| S100P | S100 calcium binding protein P | -0.0468961 |
| EPCAM | epithelial cell adhesion molecule | -0.0466749 |
| HLA-A | major histocompatibility complex, class I, A | -0.0464497 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0463292 |
| RPLP2 | ribosomal protein, large, P2 | -0.042696 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0414884 |
| S100A6 | S100 calcium binding protein A6 | -0.0402257 |
| RPL19 | ribosomal protein L19 | -0.0399869 |
| RPL28 | ribosomal protein L28 | -0.0389479 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0388716 |
| S100A10 | S100 calcium binding protein A10 | -0.0385059 |
| RPL34 | ribosomal protein L34 | -0.0384951 |
| RPS8 | ribosomal protein S8 | -0.0382928 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0373247 |
| RPS16 | ribosomal protein S16 | -0.0373238 |
| ATF5 | activating transcription factor 5 | -0.0364541 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0362115 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0359131 |
| RPL26 | ribosomal protein L26 | -0.0354024 |
| RPS29 | ribosomal protein S29 | -0.0352737 |
| RPL38 | ribosomal protein L38 | -0.0339111 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0337799 |
| RPL7A | ribosomal protein L7a | -0.0328372 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0325454 |
| RPL27 | ribosomal protein L27 | -0.0325173 |
| RPL9 | ribosomal protein L9 | -0.0324537 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0322731 |
| RPL12 | ribosomal protein L12 | -0.0317224 |
| RPL36A | ribosomal protein L36a | -0.0316834 |
| HLA-E | major histocompatibility complex, class I, E | -0.0314588 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0312965 |
| DEK | DEK proto-oncogene | -0.0312468 |
| GSTP1 | glutathione S-transferase pi 1 | -0.030988 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303113 |
| RPS20 | ribosomal protein S20 | -0.0300847 |
| B2M | beta-2-microglobulin | -0.0299221 |
| RPL32 | ribosomal protein L32 | -0.0290486 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0287884 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0287067 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0283915 |
| TMC5 | transmembrane channel-like 5 | -0.0278174 |
| RPL35 | ribosomal protein L35 | -0.02764 |
| UBB | ubiquitin B | -0.0267825 |
| SEC61G | Sec61 gamma subunit | -0.0263728 |
| SERF2 | small EDRK-rich factor 2 | -0.025986 |
| RRBP1 | ribosome binding protein 1 | -0.0256131 |
| H3-3B | H3.3 histone B | -0.0251375 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0249937 |
| IER3 | immediate early response 3 | -0.0246014 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0242469 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0238371 |
| RPL8 | ribosomal protein L8 | -0.0235672 |
| RPL37 | ribosomal protein L37 | -0.0233698 |
| RPL37A | ribosomal protein L37a | -0.0233416 |
| GNAS | GNAS complex locus | -0.0233081 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0232851 |
| HMGB1 | high mobility group box 1 | -0.023229 |
| RPS27A | ribosomal protein S27a | -0.0230707 |
| RPL36 | ribosomal protein L36 | -0.0227152 |
| HLA-B | major histocompatibility complex, class I, B | -0.022359 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0222755 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0220044 |
| RPS23 | ribosomal protein S23 | -0.0219893 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0219208 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0219105 |
| TMEM123 | transmembrane protein 123 | -0.0218429 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0217327 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0215107 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | -0.0214757 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0212506 |
| CLDN4 | claudin 4 | -0.021205 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0209486 |
| RPS15 | ribosomal protein S15 | -0.0208858 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0208006 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0206483 |
| RPL31 | ribosomal protein L31 | -0.0206147 |
| RPL5 | ribosomal protein L5 | -0.0205654 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0204525 |
| HLA-C | major histocompatibility complex, class I, C | -0.020247 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0200175 |
| KLF6 | Kruppel-like factor 6 | -0.0199241 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0197567 |
