| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.22233 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.146594 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.109538 |
| FAT1 | FAT atypical cadherin 1 | 0.0952477 |
| FLNB | filamin B, beta | 0.0894748 |
| KRT18 | keratin 18, type I | 0.0863069 |
| ITGA6 | integrin, alpha 6 | 0.0819719 |
| KRT8 | keratin 8, type II | 0.0785662 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0752044 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0706879 |
| TXNIP | thioredoxin interacting protein | 0.0704715 |
| NDRG1 | N-myc downstream regulated 1 | 0.0697918 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0686551 |
| RPL3 | ribosomal protein L3 | 0.0649962 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0648016 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0622284 |
| ONECUT3 | one cut homeobox 3 | 0.06087 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0568052 |
| FAM13A | family with sequence similarity 13, member A | 0.0553737 |
| ANKRD11 | ankyrin repeat domain 11 | 0.054773 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0528727 |
| CALR | calreticulin | 0.0527277 |
| PTMA | prothymosin, alpha | 0.0510913 |
| AREG | amphiregulin | 0.0503755 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0501765 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0471419 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0448304 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0441726 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0440303 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0434141 |
| PLEC | plectin | 0.0430347 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0426984 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0424685 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0420985 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.041359 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0395295 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0393837 |
| LMO7 | LIM domain 7 | 0.039327 |
| MED13L | mediator complex subunit 13-like | 0.0390808 |
| MYO5B | myosin VB | 0.0390546 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0389616 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0377669 |
| ASPH | aspartate beta-hydroxylase | 0.0376227 |
| MINK1 | misshapen-like kinase 1 | 0.0372222 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0367934 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0362929 |
| RPS12 | ribosomal protein S12 | 0.035606 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0348679 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0341431 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0341194 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0340584 |
| MED13 | mediator complex subunit 13 | 0.0337824 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0336961 |
| SETD5 | SET domain containing 5 | 0.033598 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0334774 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0334599 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0331566 |
| MT2A | metallothionein 2A | 0.0329775 |
| RNF145 | ring finger protein 145 | 0.0318241 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0317471 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.031328 |
| EREG | epiregulin | 0.0311517 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0311036 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306707 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0305301 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.030485 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0303173 |
| RREB1 | ras responsive element binding protein 1 | 0.0302617 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) | 0.0297972 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0297965 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0296276 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.0296145 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0295752 |
| CCNY | cyclin Y | 0.0294733 |
| TMSB4X | thymosin beta 4, X-linked | 0.0291837 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0288113 |
| PNN | pinin, desmosome associated protein | 0.0286048 |
| DSPP | dentin sialophosphoprotein | 0.0281271 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0280915 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0280438 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0279525 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0278827 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0275913 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0273826 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0270976 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0267191 |
| APP | amyloid beta (A4) precursor protein | 0.0265754 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0261509 |
| MLEC | malectin | 0.0259352 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0258139 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0254163 |
| MYO18A | myosin XVIIIA | 0.0252944 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0251526 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0250773 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0249672 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0249134 |
| TNS4 | tensin 4 | 0.0248845 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0247824 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0247631 |
| RNF43 | ring finger protein 43 | 0.0246767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.163035 |
| NPSR1 | neuropeptide S receptor 1 | -0.100037 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0923869 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0598208 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0581672 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0559154 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0503942 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0490919 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0461717 |
| AHNAK | AHNAK nucleoprotein | -0.0454404 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0439582 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0428077 |
| RPS24 | ribosomal protein S24 | -0.040427 |
| GPHN | gephyrin | -0.0393332 |
| VCL | vinculin | -0.0337372 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322965 |
| CCND1 | cyclin D1 | -0.0321829 |
| TMSB10 | thymosin beta 10 | -0.0312669 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0307316 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0302137 |
| DSTN | destrin (actin depolymerizing factor) | -0.0299604 |
| FHIT | fragile histidine triad | -0.0253226 |
| RPL4 | ribosomal protein L4 | -0.0252837 |
| TFRC | transferrin receptor | -0.0250817 |
| LDHA | lactate dehydrogenase A | -0.0242533 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0241624 |
| HMGB1 | high mobility group box 1 | -0.0239321 |
| CD44 | CD44 molecule (Indian blood group) | -0.022807 |
| IGFL2 | IGF-like family member 2 | -0.0227859 |
| IER3 | immediate early response 3 | -0.0222321 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0219799 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0215706 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0214164 |
| RPLP1 | ribosomal protein, large, P1 | -0.0208086 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0207108 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0205396 |
| DEK | DEK proto-oncogene | -0.0204864 |
| TPM4 | tropomyosin 4 | -0.0200094 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0200016 |
| POTEF | POTE ankyrin domain family, member F | -0.019801 |
| SERINC5 | serine incorporator 5 | -0.0196582 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0193997 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0193069 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0190365 |
| ABLIM1 | actin binding LIM protein 1 | -0.0189419 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0185228 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0182503 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0181963 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0180787 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.018009 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0179808 |
| MYO1D | myosin ID | -0.0179419 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0178287 |
| RNF217 | ring finger protein 217 | -0.0174058 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0172753 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0170638 |
| FRMD5 | FERM domain containing 5 | -0.0166014 |
| RPS20 | ribosomal protein S20 | -0.0165077 |
| TMEM123 | transmembrane protein 123 | -0.0164557 |
| BSG | basigin (Ok blood group) | -0.0163934 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0163904 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0161196 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0159935 |
| CENPF | centromere protein F, 350/400kDa | -0.0156803 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0156554 |
| ARF4 | ADP-ribosylation factor 4 | -0.0155456 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0154289 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0154142 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0153686 |
| SPIDR | scaffolding protein involved in DNA repair | -0.015347 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0151705 |
| CDK6 | cyclin-dependent kinase 6 | -0.0150643 |
| PKP4 | plakophilin 4 | -0.0149637 |
| MECOM | MDS1 and EVI1 complex locus | -0.0149279 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0149112 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0147696 |
| HMGA1 | high mobility group AT-hook 1 | -0.0146165 |
| FBXO33 | F-box protein 33 | -0.014602 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0145464 |
| FBXO34 | F-box protein 34 | -0.014419 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0140494 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0140128 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0140028 |
| RPS2 | ribosomal protein S2 | -0.0139799 |
| WWC1 | WW and C2 domain containing 1 | -0.0139639 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0138248 |
| MTAP | methylthioadenosine phosphorylase | -0.0138237 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0138001 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.013787 |
| FOXP1 | forkhead box P1 | -0.0136256 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0135919 |
| LSAMP | limbic system-associated membrane protein | -0.013536 |
| LAMA4 | laminin, alpha 4 | -0.0133116 |
| KLK10 | kallikrein-related peptidase 10 | -0.0133067 |
| TUBA1B | tubulin, alpha 1b | -0.0131402 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0130455 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0130288 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0129672 |
| CENPE | centromere protein E, 312kDa | -0.012873 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0128718 |
