| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.170157 |
| FLNB | filamin B, beta | 0.113004 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.106816 |
| FAT1 | FAT atypical cadherin 1 | 0.0958824 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0896461 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0894667 |
| RPL3 | ribosomal protein L3 | 0.0638456 |
| MKI67 | marker of proliferation Ki-67 | 0.0638428 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0633836 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0632876 |
| TXNRD1 | thioredoxin reductase 1 | 0.0608663 |
| ITGA6 | integrin, alpha 6 | 0.0587438 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0578209 |
| GOLGA4 | golgin A4 | 0.0531975 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0515951 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0507128 |
| MYOF | myoferlin | 0.0471851 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0469821 |
| RPL23 | ribosomal protein L23 | 0.0454016 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0442272 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0436832 |
| SHROOM3 | shroom family member 3 | 0.0435801 |
| PKP2 | plakophilin 2 | 0.0429202 |
| YBX3 | Y box binding protein 3 | 0.0420367 |
| PRELID2 | PRELI domain containing 2 | 0.0420255 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0401185 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0379194 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0373922 |
| VEGFA | vascular endothelial growth factor A | 0.0372726 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0366508 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0364733 |
| SMAD3 | SMAD family member 3 | 0.0358018 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0351665 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0348193 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0346847 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0343244 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0339806 |
| RPL5 | ribosomal protein L5 | 0.0339687 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.033966 |
| EPHA2 | EPH receptor A2 | 0.0336477 |
| SETD5 | SET domain containing 5 | 0.0335262 |
| RACK1 | receptor for activated C kinase 1 | 0.033451 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0324112 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0323854 |
| RNF145 | ring finger protein 145 | 0.0319552 |
| FOXO1 | forkhead box O1 | 0.03175 |
| CANX | calnexin | 0.0309845 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0309825 |
| OGA | O-GlcNAcase | 0.0306868 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0304387 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0304346 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0303954 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0302334 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0299837 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0293441 |
| LRRC1 | leucine rich repeat containing 1 | 0.0292096 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0291977 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0290761 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.029056 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0290542 |
| CALB1 | calbindin 1, 28kDa | 0.0289848 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0281659 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0279776 |
| CENPF | centromere protein F, 350/400kDa | 0.0279206 |
| PLAC8 | placenta-specific 8 | 0.0275691 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0272821 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0272786 |
| CDK19 | cyclin-dependent kinase 19 | 0.0268027 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.02677 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0266624 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0260002 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0258646 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.025859 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0256792 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0254256 |
| AFDN | afadin, adherens junction formation factor | 0.0253515 |
| RAD21 | RAD21 homolog (S. pombe) | 0.025118 |
| PTEN | phosphatase and tensin homolog | 0.0244737 |
| PCDHB16 | protocadherin beta 16 | 0.0243256 |
| GDF15 | growth differentiation factor 15 | 0.0242607 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.024214 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0240989 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0240737 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0239016 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0238328 |
| MED13L | mediator complex subunit 13-like | 0.0238279 |
| WWC1 | WW and C2 domain containing 1 | 0.0237498 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0236474 |
| NKTR | natural killer cell triggering receptor | 0.023594 |
| ZNF292 | zinc finger protein 292 | 0.0235288 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0234789 |
| KIF16B | kinesin family member 16B | 0.0232652 |
| HDLBP | high density lipoprotein binding protein | 0.0231284 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0228802 |
| RBM39 | RNA binding motif protein 39 | 0.0228552 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0228162 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0225236 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0224607 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0224071 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.189144 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0871521 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0734293 |
| FRMD5 | FERM domain containing 5 | -0.0549011 |
| HLA-B | major histocompatibility complex, class I, B | -0.054885 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0514791 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0488339 |
| RPS24 | ribosomal protein S24 | -0.0487878 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0462093 |
| RPL31 | ribosomal protein L31 | -0.045613 |
| RPLP2 | ribosomal protein, large, P2 | -0.0410983 |
| SERINC5 | serine incorporator 5 | -0.0399024 |
| RPLP1 | ribosomal protein, large, P1 | -0.0367015 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0366774 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0350949 |
| RPS25 | ribosomal protein S25 | -0.0317118 |
| MYO1E | myosin IE | -0.0311411 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0303735 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0292857 |
| SP100 | SP100 nuclear antigen | -0.0286841 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0285599 |
| POTEF | POTE ankyrin domain family, member F | -0.0277386 |
| S100A6 | S100 calcium binding protein A6 | -0.0268815 |
| RPL34 | ribosomal protein L34 | -0.0263919 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0257533 |
| RPL37 | ribosomal protein L37 | -0.0256802 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0256078 |
| NPSR1 | neuropeptide S receptor 1 | -0.0253432 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0251551 |
| INTS6 | integrator complex subunit 6 | -0.0246531 |
| MCU | mitochondrial calcium uniporter | -0.0242049 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0241568 |
| PERP | PERP, TP53 apoptosis effector | -0.0238521 |
| RPL35A | ribosomal protein L35a | -0.0233664 |
| RPL36A | ribosomal protein L36a | -0.023196 |
| TSPAN8 | tetraspanin 8 | -0.0225329 |
| RPL27A | ribosomal protein L27a | -0.0224857 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0224277 |
| XAF1 | XIAP associated factor 1 | -0.0213915 |
| DSG2 | desmoglein 2 | -0.0212099 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0211549 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0210085 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0208926 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0208832 |
| RPL37A | ribosomal protein L37a | -0.0200173 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0198871 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0198348 |
| RPS29 | ribosomal protein S29 | -0.0198182 |
| S100A11 | S100 calcium binding protein A11 | -0.0197794 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0194874 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0194208 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0193568 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0193242 |
| RPL38 | ribosomal protein L38 | -0.0191825 |
| NABP1 | nucleic acid binding protein 1 | -0.0190486 |
| EMP1 | epithelial membrane protein 1 | -0.0189354 |
| RIGI | RNA sensor RIG-I | -0.0186987 |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | -0.018254 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0180566 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0180554 |
| LRRC23 | leucine rich repeat containing 23 | -0.0177533 |
| CCND1 | cyclin D1 | -0.0177101 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0176859 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0174235 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0173357 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0172997 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0172551 |
| S100P | S100 calcium binding protein P | -0.0172195 |
| UBC | ubiquitin C | -0.0170002 |
| RPS21 | ribosomal protein S21 | -0.0169049 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0168824 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0164208 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0163894 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0163846 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0163021 |
| RPL9 | ribosomal protein L9 | -0.0162846 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.016259 |
| PKM | pyruvate kinase, muscle | -0.0161396 |
| HLA-A | major histocompatibility complex, class I, A | -0.0160194 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0159592 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0158968 |
| IER3 | immediate early response 3 | -0.0156263 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0156095 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0155626 |
| AEBP2 | AE binding protein 2 | -0.0155255 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0154284 |
| RNF217 | ring finger protein 217 | -0.0153662 |
| SVIL | supervillin | -0.0153644 |
| FOXO3 | forkhead box O3 | -0.0153562 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0151668 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0149538 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0148895 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0146732 |
| FBXO11 | F-box protein 11 | -0.0146702 |
| DSC3 | desmocollin 3 | -0.0145457 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.014225 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.01412 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0140027 |
| RPS11 | ribosomal protein S11 | -0.0139851 |
| RPL39 | ribosomal protein L39 | -0.0139821 |
