| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.115884 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0739405 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0563073 |
| FLNB | filamin B, beta | 0.055409 |
| RAI1 | retinoic acid induced 1 | 0.0550027 |
| FMNL2 | formin-like 2 | 0.0511357 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.048881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0469191 |
| TXNRD1 | thioredoxin reductase 1 | 0.0426632 |
| LOXL2 | lysyl oxidase-like 2 | 0.0422564 |
| UPP1 | uridine phosphorylase 1 | 0.0409879 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0408286 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0399011 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0381601 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0370713 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0365252 |
| NAV2 | neuron navigator 2 | 0.0363488 |
| CAPRIN2 | caprin family member 2 | 0.0356892 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0356537 |
| EZR | ezrin | 0.0352819 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0352746 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.033876 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0332635 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0327161 |
| TMEM41B | transmembrane protein 41B | 0.0322634 |
| CANX | calnexin | 0.0314832 |
| APP | amyloid beta (A4) precursor protein | 0.0306022 |
| SPAG9 | sperm associated antigen 9 | 0.0305 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0278474 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0276975 |
| KLF6 | Kruppel-like factor 6 | 0.0275556 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0272902 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0271097 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0270146 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0269742 |
| FNIP1 | folliculin interacting protein 1 | 0.0262484 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.025391 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0246618 |
| ANGPTL4 | angiopoietin-like 4 | 0.0245336 |
| SQSTM1 | sequestosome 1 | 0.0242245 |
| PLEC | plectin | 0.0241514 |
| EREG | epiregulin | 0.0240688 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0240207 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0238543 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.023595 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0234488 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234463 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0234243 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0231701 |
| OGA | O-GlcNAcase | 0.022764 |
| YEATS2 | YEATS domain containing 2 | 0.0225218 |
| TMSB4X | thymosin beta 4, X-linked | 0.0225216 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0225045 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0217822 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0215486 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0215294 |
| ANXA1 | annexin A1 | 0.0214947 |
| FDPS | farnesyl diphosphate synthase | 0.0214519 |
| PODXL | podocalyxin-like | 0.0214236 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0213235 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0208837 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0204052 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0202967 |
| NDRG1 | N-myc downstream regulated 1 | 0.0201456 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0201343 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0194778 |
| PYGL | phosphorylase, glycogen, liver | 0.0192114 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0190147 |
| MKI67 | marker of proliferation Ki-67 | 0.019013 |
| PLK2 | polo-like kinase 2 | 0.0189333 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0189119 |
| GSK3B | glycogen synthase kinase 3 beta | 0.018801 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0185693 |
| SMAD3 | SMAD family member 3 | 0.0183295 |
| ACTN1 | actinin, alpha 1 | 0.0182796 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0182075 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0181775 |
| RPL3 | ribosomal protein L3 | 0.0181127 |
| ANXA2 | annexin A2 | 0.0180998 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0180347 |
| MED15 | mediator complex subunit 15 | 0.0179668 |
| HDLBP | high density lipoprotein binding protein | 0.0179407 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0177974 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.017685 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0175417 |
| VEGFA | vascular endothelial growth factor A | 0.0175396 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0174013 |
| USP34 | ubiquitin specific peptidase 34 | 0.0173804 |
| CEP250 | centrosomal protein 250kDa | 0.0173645 |
| RGS4 | regulator of G-protein signaling 4 | 0.0173415 |
| DENND1A | DENN/MADD domain containing 1A | 0.0173391 |
| CDK19 | cyclin-dependent kinase 19 | 0.0173266 |
| ARRDC3 | arrestin domain containing 3 | 0.017225 |
| CLTC | clathrin, heavy chain (Hc) | 0.0172194 |
| HDAC9 | histone deacetylase 9 | 0.0171868 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0171241 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0170634 |
| NONO | non-POU domain containing, octamer-binding | 0.0169951 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0168293 |
| LPIN1 | lipin 1 | 0.0166966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0734474 |
| MT2A | metallothionein 2A | -0.0695923 |
| TMSB10 | thymosin beta 10 | -0.0681146 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0587575 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0509801 |
| CADM2 | cell adhesion molecule 2 | -0.0483604 |
| POTEF | POTE ankyrin domain family, member F | -0.042436 |
| CD44 | CD44 molecule (Indian blood group) | -0.0403518 |
| TP63 | tumor protein p63 | -0.0397589 |
| HMGA1 | high mobility group AT-hook 1 | -0.0375689 |
| HLA-B | major histocompatibility complex, class I, B | -0.0373326 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0367005 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0352403 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0299908 |
| RIGI | RNA sensor RIG-I | -0.0295897 |
| FTL | ferritin, light polypeptide | -0.0295179 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0270176 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0264448 |
| PTMA | prothymosin, alpha | -0.0252236 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0247225 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.023998 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0235383 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0232153 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0229757 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.022538 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0218384 |
| RPL35A | ribosomal protein L35a | -0.0216621 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0209045 |
| RPS19 | ribosomal protein S19 | -0.020472 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0204572 |
| SP100 | SP100 nuclear antigen | -0.0204284 |
| RPL36 | ribosomal protein L36 | -0.020318 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0199947 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0199421 |
| DPH6 | diphthamine biosynthesis 6 | -0.0188444 |
| RPL23 | ribosomal protein L23 | -0.0187649 |
| ENO1 | enolase 1, (alpha) | -0.0184639 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0182723 |
| PLSCR1 | phospholipid scramblase 1 | -0.0179471 |
| DEK | DEK proto-oncogene | -0.0175115 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0174659 |
| HMGB1 | high mobility group box 1 | -0.0168947 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0168699 |
| S100A9 | S100 calcium binding protein A9 | -0.0166631 |
| PMP22 | peripheral myelin protein 22 | -0.0166196 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0164976 |
| RPLP2 | ribosomal protein, large, P2 | -0.0162065 |
| TPI1 | triosephosphate isomerase 1 | -0.0161825 |
| RPL12 | ribosomal protein L12 | -0.0160768 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0159269 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0155774 |
| RPS6 | ribosomal protein S6 | -0.0152916 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0152117 |
| RPL19 | ribosomal protein L19 | -0.0149783 |
| RPLP1 | ribosomal protein, large, P1 | -0.014885 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0148279 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0148035 |
| PKM | pyruvate kinase, muscle | -0.0145711 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0145696 |
| PFN1 | profilin 1 | -0.0144219 |
| RPS24 | ribosomal protein S24 | -0.0141412 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0140293 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0139449 |
| PCBP2 | poly(rC) binding protein 2 | -0.013725 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0136552 |
| RAD51B | RAD51 paralog B | -0.0136318 |
| CCNL1 | cyclin L1 | -0.0135592 |
| SRGN | serglycin | -0.0133637 |
| MT1E | metallothionein 1E | -0.0132872 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0131679 |
| HLA-A | major histocompatibility complex, class I, A | -0.0130034 |
| RPS14 | ribosomal protein S14 | -0.0128613 |
| RNF213 | ring finger protein 213 | -0.0128337 |
| RPL28 | ribosomal protein L28 | -0.0125599 |
| RPS29 | ribosomal protein S29 | -0.0124308 |
| RPL35 | ribosomal protein L35 | -0.0122122 |
| ZNF292 | zinc finger protein 292 | -0.0119527 |
| RPS5 | ribosomal protein S5 | -0.0118925 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0118118 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0117157 |
| TMEM123 | transmembrane protein 123 | -0.0116981 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0114435 |
| RBM25 | RNA binding motif protein 25 | -0.0114157 |
| RPS20 | ribosomal protein S20 | -0.011413 |
| BSG | basigin (Ok blood group) | -0.011313 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0112899 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0112342 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0110336 |
| RPS21 | ribosomal protein S21 | -0.010888 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0105401 |
| XAF1 | XIAP associated factor 1 | -0.0104216 |
| RPL8 | ribosomal protein L8 | -0.0103905 |
| TAPBP | TAP binding protein (tapasin) | -0.0103038 |
| MYADM | myeloid-associated differentiation marker | -0.0102836 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0102263 |
| UBB | ubiquitin B | -0.0101891 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0100373 |
| ETNK1 | ethanolamine kinase 1 | -0.0100295 |
| CDK6 | cyclin-dependent kinase 6 | -0.00998457 |
| RPS2 | ribosomal protein S2 | -0.00984883 |
