| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cyclosporin A_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.141627 |
| PLEC | plectin | 0.139757 |
| LOC112694756 | uncharaterized LOC112694756 | 0.119676 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.109222 |
| EGR1 | early growth response 1 | 0.106422 |
| LAMB3 | laminin, beta 3 | 0.105827 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.104348 |
| H1-0 | H1.0 linker histone | 0.0959367 |
| LAMC2 | laminin, gamma 2 | 0.0894822 |
| ARRDC3 | arrestin domain containing 3 | 0.0822166 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0789338 |
| TXNRD1 | thioredoxin reductase 1 | 0.0742434 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0690567 |
| ANXA2 | annexin A2 | 0.0690166 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0664458 |
| PKM | pyruvate kinase, muscle | 0.0649585 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0645086 |
| LMO7 | LIM domain 7 | 0.0641645 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0633398 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0623452 |
| SPAG9 | sperm associated antigen 9 | 0.0622486 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0584433 |
| SMAD3 | SMAD family member 3 | 0.0584382 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0581705 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0561129 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.055334 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0552631 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0547204 |
| PGK1 | phosphoglycerate kinase 1 | 0.0534823 |
| RPS3 | ribosomal protein S3 | 0.0527219 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0509696 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0492936 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0490274 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0482571 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0473939 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0460011 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0448922 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0442975 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0440937 |
| MYO1E | myosin IE | 0.043251 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0431233 |
| ANXA1 | annexin A1 | 0.0427882 |
| RPL3 | ribosomal protein L3 | 0.0426984 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0415388 |
| ANO6 | anoctamin 6 | 0.0412706 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0410605 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0406088 |
| B2M | beta-2-microglobulin | 0.0404476 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0403902 |
| DENND4A | DENN/MADD domain containing 4A | 0.0402682 |
| HDLBP | high density lipoprotein binding protein | 0.0395481 |
| KRT18 | keratin 18, type I | 0.0393832 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0393131 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.039084 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0389173 |
| RAB7A | RAB7A, member RAS oncogene family | 0.038739 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0385269 |
| KRT8 | keratin 8, type II | 0.0383759 |
| CTTN | cortactin | 0.0380603 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0379808 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0366881 |
| MCL1 | myeloid cell leukemia 1 | 0.0360134 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0357186 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0356499 |
| BRD2 | bromodomain containing 2 | 0.0356308 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0354089 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0353382 |
| EMP1 | epithelial membrane protein 1 | 0.0351629 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0350287 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0350022 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0347727 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0345767 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0345212 |
| MYO5B | myosin VB | 0.0341397 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0339191 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0339189 |
| MKI67 | marker of proliferation Ki-67 | 0.0337285 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0337003 |
| INTS6 | integrator complex subunit 6 | 0.0336767 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0329788 |
| MED15 | mediator complex subunit 15 | 0.0327513 |
| CTBP2 | C-terminal binding protein 2 | 0.0324134 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.0321367 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0320797 |
| EP300 | E1A binding protein p300 | 0.0317455 |
| YEATS2 | YEATS domain containing 2 | 0.0313735 |
| VEGFA | vascular endothelial growth factor A | 0.0309931 |
| APP | amyloid beta (A4) precursor protein | 0.0307167 |
| SMTN | smoothelin | 0.0304879 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.03028 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0302406 |
| RNF169 | ring finger protein 169 | 0.0295128 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0294702 |
| DSPP | dentin sialophosphoprotein | 0.0293762 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0289796 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0287437 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0286939 |
| FAT1 | FAT atypical cadherin 1 | 0.0286194 |
| UVRAG | UV radiation resistance associated | 0.0284854 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0283298 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.164394 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115125 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.114448 |
| MT2A | metallothionein 2A | -0.0712405 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0710932 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0613999 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0504326 |
| RPLP1 | ribosomal protein, large, P1 | -0.0491567 |
| CDCP1 | CUB domain containing protein 1 | -0.0475975 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0461732 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0396785 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0390794 |
| TMSB10 | thymosin beta 10 | -0.0377061 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0371028 |
| TMEM165 | transmembrane protein 165 | -0.0369932 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0366429 |
| IER3 | immediate early response 3 | -0.0353898 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0353744 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0353506 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0349632 |
| CD163L1 | CD163 molecule-like 1 | -0.0348147 |
| RPS6 | ribosomal protein S6 | -0.0341824 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0339977 |
| SEC61G | Sec61 gamma subunit | -0.033973 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0338767 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.033666 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0287623 |
| SEC24D | SEC24 family member D | -0.0282942 |
| RPS25 | ribosomal protein S25 | -0.0277036 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0275964 |
| HM13 | histocompatibility (minor) 13 | -0.026972 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0257932 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0254016 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0246731 |
| S100A10 | S100 calcium binding protein A10 | -0.0245268 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0244988 |
| GNAS | GNAS complex locus | -0.0241288 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0239462 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0238182 |
| GOLGA4 | golgin A4 | -0.0234002 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0229168 |
| HMGA1 | high mobility group AT-hook 1 | -0.0226417 |
| SCFD1 | sec1 family domain containing 1 | -0.0223304 |
| VCL | vinculin | -0.0221929 |
| RTN4 | reticulon 4 | -0.0218803 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0215597 |
| CSTB | cystatin B (stefin B) | -0.0213783 |
| RPL21 | ribosomal protein L21 | -0.0209015 |
| SEPTIN10 | septin 10 | -0.0206161 |
| RPL35A | ribosomal protein L35a | -0.0206121 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0205941 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0205633 |
| CCNL1 | cyclin L1 | -0.0204168 |
| OSMR | oncostatin M receptor | -0.0203466 |
| AGR2 | anterior gradient 2 | -0.0202881 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0202379 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0201653 |
| TRIM56 | tripartite motif containing 56 | -0.0199291 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0198708 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0198066 |
| S100A6 | S100 calcium binding protein A6 | -0.0191723 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0191006 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0186496 |
| SUMF1 | sulfatase modifying factor 1 | -0.0182186 |
| FBXO28 | F-box protein 28 | -0.0182037 |
| POTEF | POTE ankyrin domain family, member F | -0.0181794 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0179867 |
| EFNA5 | ephrin-A5 | -0.0178815 |
| TRAM1 | translocation associated membrane protein 1 | -0.0178129 |
| ASPH | aspartate beta-hydroxylase | -0.0177374 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0176996 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0171782 |
| SHTN1 | shootin 1 | -0.0170657 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0169278 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0165949 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0165925 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.016544 |
| PDE8A | phosphodiesterase 8A | -0.0165311 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0163915 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0162769 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0162583 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0162337 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0161754 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0161521 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0161023 |
| ENSA | endosulfine alpha | -0.0158974 |
| SECISBP2L | SECIS binding protein 2-like | -0.0158794 |
| RPS19 | ribosomal protein S19 | -0.015876 |
| BPTF | bromodomain PHD finger transcription factor | -0.0158275 |
| MT1X | metallothionein 1X | -0.0157347 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.015731 |
| SEC24A | SEC24 family member A | -0.0156149 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0155987 |
| CCND1 | cyclin D1 | -0.0155953 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0154636 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0153804 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0153006 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0152483 |
| ZNF721 | zinc finger protein 721 | -0.0151784 |
| RBM25 | RNA binding motif protein 25 | -0.0151499 |
