| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cyclosporin A_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.121559 |
| GRB10 | growth factor receptor-bound protein 10 | 0.117228 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.108962 |
| VEGFA | vascular endothelial growth factor A | 0.0987509 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.082647 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0807349 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.073572 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0719101 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0697741 |
| NAV2 | neuron navigator 2 | 0.0692502 |
| VIM | vimentin | 0.0649178 |
| FLNB | filamin B, beta | 0.0644136 |
| NDRG1 | N-myc downstream regulated 1 | 0.0627463 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.061377 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0612651 |
| FAM13A | family with sequence similarity 13, member A | 0.0577514 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0577259 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0549468 |
| COPA | coatomer protein complex, subunit alpha | 0.0532677 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0510006 |
| ANXA2 | annexin A2 | 0.0504787 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0488294 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0476955 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0452798 |
| OGA | O-GlcNAcase | 0.0449285 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0444845 |
| RPLP0 | ribosomal protein, large, P0 | 0.0438276 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0415062 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0415002 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0393356 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0392839 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0387437 |
| SMAD3 | SMAD family member 3 | 0.038284 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0381053 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0378145 |
| CALR | calreticulin | 0.0375641 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0373876 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0373694 |
| FAM20C | family with sequence similarity 20, member C | 0.0370784 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0370092 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0366557 |
| YBX1 | Y box binding protein 1 | 0.0364662 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0362623 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.035954 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0359366 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0356333 |
| CD109 | CD109 molecule | 0.0354064 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0346498 |
| CEP250 | centrosomal protein 250kDa | 0.0334387 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0333104 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0332613 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0331297 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0324974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0321022 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0316537 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0304416 |
| CABIN1 | calcineurin binding protein 1 | 0.0301141 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0298808 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.029721 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296901 |
| NGLY1 | N-glycanase 1 | 0.0296161 |
| APP | amyloid beta (A4) precursor protein | 0.0294837 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0294366 |
| RPL23 | ribosomal protein L23 | 0.0293208 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0292525 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0290776 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0287249 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0283872 |
| ATP13A3 | ATPase type 13A3 | 0.0283481 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0282976 |
| SFTPA2 | surfactant protein A2 | 0.0280437 |
| MLPH | melanophilin | 0.0278194 |
| RPL3 | ribosomal protein L3 | 0.0276904 |
| HDLBP | high density lipoprotein binding protein | 0.0276756 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0274079 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0273171 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0271892 |
| CANX | calnexin | 0.0269855 |
| SEPTIN2 | septin 2 | 0.0265303 |
| RACK1 | receptor for activated C kinase 1 | 0.0265164 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.026072 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0259446 |
| SIK3 | SIK family kinase 3 | 0.025943 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0258194 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0254789 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0254477 |
| PTMA | prothymosin, alpha | 0.025416 |
| B2M | beta-2-microglobulin | 0.0254049 |
| FLNA | filamin A, alpha | 0.0251523 |
| FN1 | fibronectin 1 | 0.0249735 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0249255 |
| ARRDC3 | arrestin domain containing 3 | 0.0248712 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0246372 |
| RPS8 | ribosomal protein S8 | 0.0244984 |
| MYOF | myoferlin | 0.0244486 |
| PFKP | phosphofructokinase, platelet | 0.0244006 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0242745 |
| SETD5 | SET domain containing 5 | 0.0241307 |
| HELZ | helicase with zinc finger | 0.0239694 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0237256 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.126127 |
| NRG1 | neuregulin 1 | -0.0590392 |
| EFNA5 | ephrin-A5 | -0.0577926 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0543477 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0537535 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0497264 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.042488 |
| LOX | lysyl oxidase | -0.0422982 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0397546 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0377166 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.036629 |
| ANTXR2 | anthrax toxin receptor 2 | -0.035692 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0339686 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0326457 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0312508 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0311358 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0303294 |
| CDCP1 | CUB domain containing protein 1 | -0.0295942 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0286357 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0283699 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0274964 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0266523 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0262298 |
| MT2A | metallothionein 2A | -0.0259305 |
| RPS2 | ribosomal protein S2 | -0.0258588 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0254119 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0239706 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239224 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0233008 |
| HMGA2 | high mobility group AT-hook 2 | -0.0232005 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0221201 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0218176 |
| RAD51B | RAD51 paralog B | -0.0217984 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0216227 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0216133 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0212302 |
| EXOC4 | exocyst complex component 4 | -0.0206735 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0206447 |
| MECOM | MDS1 and EVI1 complex locus | -0.0204009 |
| GLIS3 | GLIS family zinc finger 3 | -0.0194617 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0192707 |
| ETV6 | ets variant 6 | -0.0191549 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.019055 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0189037 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0185639 |
| FBN1 | fibrillin 1 | -0.0184306 |
| ASPH | aspartate beta-hydroxylase | -0.018293 |
| EREG | epiregulin | -0.017974 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0178426 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0177789 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0176127 |
| DST | dystonin | -0.0176002 |
| IFI44 | interferon-induced protein 44 | -0.0175834 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0175191 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0174875 |
| ARF4 | ADP-ribosylation factor 4 | -0.017276 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0172017 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0171036 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0169322 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0168278 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0166216 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0164848 |
| FRMD4A | FERM domain containing 4A | -0.0164764 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.016444 |
| USP34 | ubiquitin specific peptidase 34 | -0.0161929 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0161807 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0159014 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0158379 |
| SYT1 | synaptotagmin I | -0.0157793 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0157194 |
| IFI44L | interferon-induced protein 44-like | -0.0156914 |
| ZNF804A | zinc finger protein 804A | -0.0155784 |
| MTSS1 | metastasis suppressor 1 | -0.0154716 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0153632 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0152931 |
| NAV3 | neuron navigator 3 | -0.01513 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0150402 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.014984 |
| TAPBP | TAP binding protein (tapasin) | -0.0149204 |
| TMEM165 | transmembrane protein 165 | -0.01474 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0147304 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0147048 |
| ATM | ATM serine/threonine kinase | -0.0146817 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0145495 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0145207 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0143272 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.014156 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0141412 |
| CDK6 | cyclin-dependent kinase 6 | -0.0140965 |
| TMEM131 | transmembrane protein 131 | -0.0140782 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.014049 |
| UBXN4 | UBX domain protein 4 | -0.0138677 |
| SEC24A | SEC24 family member A | -0.0138171 |
| IL1B | interleukin 1, beta | -0.0137761 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0137468 |
| PCBP2 | poly(rC) binding protein 2 | -0.0134986 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0134313 |
| SCFD2 | sec1 family domain containing 2 | -0.0134145 |
| EHBP1 | EH domain binding protein 1 | -0.0134123 |
| NRP1 | neuropilin 1 | -0.0134027 |
