| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cyclosporin A_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.199607 |
| NDRG1 | N-myc downstream regulated 1 | 0.106154 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0929713 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0917698 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.082209 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0810113 |
| COPA | coatomer protein complex, subunit alpha | 0.0766719 |
| GPC6 | glypican 6 | 0.0750917 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0722882 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0702837 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0699394 |
| VIM | vimentin | 0.0685373 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0648172 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0645711 |
| EGFR | epidermal growth factor receptor | 0.0615442 |
| USP3 | ubiquitin specific peptidase 3 | 0.0591553 |
| RPS16 | ribosomal protein S16 | 0.0582363 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.057568 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0572091 |
| ANXA1 | annexin A1 | 0.057021 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0567341 |
| MED13L | mediator complex subunit 13-like | 0.0563589 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0557343 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0551962 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0542002 |
| NUP58 | nucleoporin 58 | 0.0541766 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0534478 |
| FOXJ3 | forkhead box J3 | 0.0531408 |
| NCKAP1 | NCK-associated protein 1 | 0.0526441 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.051837 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0514351 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0512662 |
| HELZ | helicase with zinc finger | 0.0506903 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.050425 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0503356 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0502339 |
| FMNL2 | formin-like 2 | 0.0497065 |
| SETD5 | SET domain containing 5 | 0.0491493 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0490051 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0488021 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0481924 |
| AAK1 | AP2 associated kinase 1 | 0.0481181 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0475762 |
| MYO6 | myosin VI | 0.0475559 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0471786 |
| FUS | FUS RNA binding protein | 0.0471753 |
| ANXA5 | annexin A5 | 0.0464701 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0463798 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0463637 |
| NF1 | neurofibromin 1 | 0.0462066 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0461893 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0436686 |
| SUCO | SUN domain containing ossification factor | 0.0435304 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0433494 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0428384 |
| FMN1 | formin 1 | 0.042477 |
| NAV2 | neuron navigator 2 | 0.0424594 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0423512 |
| PLEC | plectin | 0.0422029 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0419542 |
| YTHDC1 | YTH domain containing 1 | 0.0411712 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0408368 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0407994 |
| LIMA1 | LIM domain and actin binding 1 | 0.0406555 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.040587 |
| SRP54 | signal recognition particle 54kDa | 0.0404736 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0401243 |
| UTRN | utrophin | 0.0400743 |
| ZNF451 | zinc finger protein 451 | 0.0398258 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.039295 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0392806 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0390165 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0389459 |
| RNF24 | ring finger protein 24 | 0.038713 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0386236 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0385636 |
| PHF21A | PHD finger protein 21A | 0.0382707 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.038032 |
| EP400 | E1A binding protein p400 | 0.038024 |
| PKM | pyruvate kinase, muscle | 0.0377137 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0376019 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0372041 |
| PGK1 | phosphoglycerate kinase 1 | 0.0364319 |
| STC1 | stanniocalcin 1 | 0.0363884 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0362359 |
| MT2A | metallothionein 2A | 0.0361489 |
| RREB1 | ras responsive element binding protein 1 | 0.0359551 |
| TCF12 | transcription factor 12 | 0.0356611 |
| CASC3 | cancer susceptibility candidate 3 | 0.0356408 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0350228 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0348497 |
| MYO1E | myosin IE | 0.0345339 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0344353 |
| VMP1 | vacuole membrane protein 1 | 0.0342645 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0340992 |
| AFDN | afadin, adherens junction formation factor | 0.0339814 |
| CLINT1 | clathrin interactor 1 | 0.0337832 |
| MSN | moesin | 0.0337541 |
| FLNA | filamin A, alpha | 0.0336491 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0336425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.152414 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142633 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0973888 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0661862 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0636748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0626234 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0607764 |
| RPL26 | ribosomal protein L26 | -0.0591233 |
| SQSTM1 | sequestosome 1 | -0.0587671 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.057879 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0571439 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0546313 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0536951 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0519019 |
| TXNRD1 | thioredoxin reductase 1 | -0.051026 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0499344 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0494642 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0492736 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048672 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0483881 |
| RPL19 | ribosomal protein L19 | -0.048202 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.048074 |
| RAI14 | retinoic acid induced 14 | -0.047126 |
| ABHD17C | abhydrolase domain containing 17C | -0.0467982 |
| FAM107B | family with sequence similarity 107, member B | -0.0458872 |
| IER3 | immediate early response 3 | -0.0450468 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.044223 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.044005 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0438061 |
| JUN | jun proto-oncogene | -0.0433544 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0429562 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0424688 |
| OXSR1 | oxidative stress responsive 1 | -0.0424326 |
| CDK13 | cyclin-dependent kinase 13 | -0.0423734 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0422235 |
| RPL35A | ribosomal protein L35a | -0.0412287 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0411762 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0408598 |
| MUC16 | mucin 16, cell surface associated | -0.0406485 |
| TUT7 | terminal uridylyl transferase 7 | -0.0404294 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0402907 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0389535 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0389239 |
| FBXO11 | F-box protein 11 | -0.0386344 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0384736 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0380274 |
| BCL2L1 | BCL2-like 1 | -0.0372045 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0371576 |
| RPL5 | ribosomal protein L5 | -0.035624 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0355478 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0354653 |
| AHNAK | AHNAK nucleoprotein | -0.0353758 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0350118 |
| PTGR1 | prostaglandin reductase 1 | -0.0346828 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0344885 |
| RPL4 | ribosomal protein L4 | -0.0342873 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.034057 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340491 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0338137 |
| PCBP3 | poly(rC) binding protein 3 | -0.0337829 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0337812 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0335847 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0334773 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0334007 |
| HMGA2 | high mobility group AT-hook 2 | -0.0332973 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0331804 |
| RPL12 | ribosomal protein L12 | -0.0330319 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0324435 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0323711 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0321191 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0320407 |
| LAMC2 | laminin, gamma 2 | -0.0320007 |
| KIF16B | kinesin family member 16B | -0.0319985 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0319809 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0314784 |
| DSG2 | desmoglein 2 | -0.0313879 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0305407 |
| RIGI | RNA sensor RIG-I | -0.0304497 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0301506 |
| TAOK3 | TAO kinase 3 | -0.0301138 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0300997 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0299315 |
| ABLIM1 | actin binding LIM protein 1 | -0.0296735 |
| SRGN | serglycin | -0.0294909 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0294476 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0293803 |
| BPTF | bromodomain PHD finger transcription factor | -0.0292215 |
| SP100 | SP100 nuclear antigen | -0.0292155 |
| FRMD4A | FERM domain containing 4A | -0.0290571 |
| CD2AP | CD2-associated protein | -0.0290042 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0288751 |
| METTL15 | methyltransferase like 15 | -0.0288336 |
| MSH3 | mutS homolog 3 | -0.0287741 |
| FHIT | fragile histidine triad | -0.0286864 |
| NHSL1 | NHS-like 1 | -0.0286837 |
| JUP | junction plakoglobin | -0.0286553 |
| FOXO1 | forkhead box O1 | -0.0284163 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0281779 |
| OSMR | oncostatin M receptor | -0.0276965 |
| FNIP1 | folliculin interacting protein 1 | -0.0275344 |
