| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.141783 |
| NDRG1 | N-myc downstream regulated 1 | 0.137224 |
| PLEC | plectin | 0.129819 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.129805 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.122531 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.12114 |
| FN1 | fibronectin 1 | 0.102499 |
| G0S2 | G0/G1 switch 2 | 0.101331 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0843086 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0732145 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0639477 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0628951 |
| LAMB3 | laminin, beta 3 | 0.0619909 |
| UPP1 | uridine phosphorylase 1 | 0.053202 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0528166 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0513298 |
| LAMC2 | laminin, gamma 2 | 0.0483924 |
| ARRDC3 | arrestin domain containing 3 | 0.047494 |
| RACK1 | receptor for activated C kinase 1 | 0.0467418 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0451038 |
| FAM13A | family with sequence similarity 13, member A | 0.0440624 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0428768 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0419923 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0406249 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.039727 |
| KRT18 | keratin 18, type I | 0.0397038 |
| COPA | coatomer protein complex, subunit alpha | 0.0393565 |
| MSN | moesin | 0.0389593 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.038807 |
| RPL3 | ribosomal protein L3 | 0.0379743 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.037826 |
| EGR1 | early growth response 1 | 0.0358183 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0356749 |
| TFG | TRK-fused gene | 0.035596 |
| FOSL1 | FOS-like antigen 1 | 0.0350876 |
| QKI | QKI, KH domain containing, RNA binding | 0.0349069 |
| DUSP10 | dual specificity phosphatase 10 | 0.034812 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0345141 |
| YBX1 | Y box binding protein 1 | 0.0344099 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0342147 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.033677 |
| ANXA5 | annexin A5 | 0.0336353 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.033529 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0331762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.033039 |
| FLNA | filamin A, alpha | 0.0324148 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0323522 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0321598 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0320685 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.031344 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0308698 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.030256 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0296862 |
| MED15 | mediator complex subunit 15 | 0.0293178 |
| ANXA1 | annexin A1 | 0.0292685 |
| NUP58 | nucleoporin 58 | 0.0291001 |
| PLAU | plasminogen activator, urokinase | 0.029023 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.028185 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0281479 |
| NONO | non-POU domain containing, octamer-binding | 0.0275408 |
| CCNL1 | cyclin L1 | 0.0269183 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.026698 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0266757 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0262525 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0262419 |
| LRATD2 | LRAT domain containing 2 | 0.0261607 |
| WTAP | Wilms tumor 1 associated protein | 0.0259958 |
| MXD1 | MAX dimerization protein 1 | 0.0256875 |
| FLNB | filamin B, beta | 0.0253554 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0249558 |
| MKI67 | marker of proliferation Ki-67 | 0.0245922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0242801 |
| RPLP0 | ribosomal protein, large, P0 | 0.0238145 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0237527 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0236218 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0233252 |
| DBN1 | drebrin 1 | 0.0229404 |
| RNF145 | ring finger protein 145 | 0.022797 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0225608 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.022556 |
| ANXA2 | annexin A2 | 0.0217371 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0215559 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0214165 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0203968 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0203935 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0203486 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.020325 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0202565 |
| RPS10 | ribosomal protein S10 | 0.0199931 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0199152 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0197184 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0195486 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0189487 |
| B2M | beta-2-microglobulin | 0.0189411 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0185796 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0183043 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0182024 |
| SPAG5 | sperm associated antigen 5 | 0.0180573 |
| HMGB2 | high mobility group box 2 | 0.0178938 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0175744 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.219083 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.212699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178148 |
| TMSB10 | thymosin beta 10 | -0.141129 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.137582 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.122834 |
| AHNAK | AHNAK nucleoprotein | -0.109817 |
| POTEF | POTE ankyrin domain family, member F | -0.109649 |
| S100A6 | S100 calcium binding protein A6 | -0.0916418 |
| PTMA | prothymosin, alpha | -0.0863042 |
| ENO1 | enolase 1, (alpha) | -0.0846259 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0835296 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0780296 |
| FBXO32 | F-box protein 32 | -0.07769 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0706046 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0702912 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0682542 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0678964 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0651336 |
| LDHA | lactate dehydrogenase A | -0.0649976 |
| RPS27A | ribosomal protein S27a | -0.0634749 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0600722 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0597612 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0591769 |
| CCND1 | cyclin D1 | -0.0558551 |
| EFNA5 | ephrin-A5 | -0.0541298 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0538317 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.053446 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0506184 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0476586 |
| EPCAM | epithelial cell adhesion molecule | -0.0452627 |
| VIM | vimentin | -0.0449398 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.044837 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.043402 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0427653 |
| CD2AP | CD2-associated protein | -0.040952 |
| TPM4 | tropomyosin 4 | -0.0408668 |
| RPLP2 | ribosomal protein, large, P2 | -0.0407027 |
| MAP4 | microtubule-associated protein 4 | -0.0402916 |
| MAP1B | microtubule-associated protein 1B | -0.0395318 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0391716 |
| RNF213 | ring finger protein 213 | -0.038259 |
| DSG2 | desmoglein 2 | -0.0377221 |
| RBM25 | RNA binding motif protein 25 | -0.0376503 |
| RPS24 | ribosomal protein S24 | -0.0371227 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0371022 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0359029 |
| LMO7 | LIM domain 7 | -0.0357535 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0351955 |
| PCBP2 | poly(rC) binding protein 2 | -0.0348664 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0345445 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0345444 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0344857 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0344598 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0342755 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.03416 |
| FTL | ferritin, light polypeptide | -0.0339803 |
| F11R | F11 receptor | -0.0339671 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.03375 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0337233 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0330681 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0328892 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0328266 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0328075 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0327416 |
| RBM47 | RNA binding motif protein 47 | -0.031785 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0317033 |
| RAD51B | RAD51 paralog B | -0.0314576 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0314385 |
| SDC4 | syndecan 4 | -0.0312761 |
| FBXO34 | F-box protein 34 | -0.0308295 |
| MYO1E | myosin IE | -0.0306098 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0303239 |
| RHOA | ras homolog family member A | -0.0299527 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0299003 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0297333 |
| ERBIN | erbb2 interacting protein | -0.0296161 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0294026 |
| RPS29 | ribosomal protein S29 | -0.029356 |
| HLA-A | major histocompatibility complex, class I, A | -0.0290898 |
| NF1 | neurofibromin 1 | -0.0280895 |
| HLA-E | major histocompatibility complex, class I, E | -0.0279721 |
| FHIT | fragile histidine triad | -0.0279024 |
| ETV6 | ets variant 6 | -0.0278533 |
| GNAS | GNAS complex locus | -0.027433 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0272504 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0272193 |
| RPS25 | ribosomal protein S25 | -0.0266822 |
| GOLGB1 | golgin B1 | -0.0266178 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.026573 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0265476 |
| RPLP1 | ribosomal protein, large, P1 | -0.0265209 |
| FRMD5 | FERM domain containing 5 | -0.0265124 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0264452 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0263731 |
| CSTB | cystatin B (stefin B) | -0.0263272 |
| MX2 | MX dynamin-like GTPase 2 | -0.0260877 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0259074 |
| RPS13 | ribosomal protein S13 | -0.0256653 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0256522 |
