| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the Cyclosporin A_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.24176 |
| GPC6 | glypican 6 | 0.15906 |
| ATP13A3 | ATPase type 13A3 | 0.142677 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.138188 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.137085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.133347 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.13167 |
| ERBIN | erbb2 interacting protein | 0.119637 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.114803 |
| GOLGA4 | golgin A4 | 0.113068 |
| ACTG1 | actin gamma 1 | 0.101642 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0972048 |
| SPAG9 | sperm associated antigen 9 | 0.092613 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0916569 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0908366 |
| HDLBP | high density lipoprotein binding protein | 0.0897025 |
| CTBP2 | C-terminal binding protein 2 | 0.0862343 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0854439 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0835234 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0829993 |
| TXNRD1 | thioredoxin reductase 1 | 0.0822723 |
| RPL26 | ribosomal protein L26 | 0.0819607 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0804715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0777868 |
| RBM39 | RNA binding motif protein 39 | 0.0739087 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0733912 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0721503 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0706185 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0702507 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0573436 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0565755 |
| GNAS | GNAS complex locus | 0.05543 |
| PTK2 | protein tyrosine kinase 2 | 0.0532383 |
| RPL35A | ribosomal protein L35a | 0.0522165 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0508386 |
| ZNF292 | zinc finger protein 292 | 0.0489032 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0488438 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0485551 |
| FLNB | filamin B, beta | 0.0482599 |
| STC1 | stanniocalcin 1 | 0.0458476 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0410181 |
| RORA | RAR-related orphan receptor A | 0.0408078 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0403498 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0397242 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0395283 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0394301 |
| OGA | O-GlcNAcase | 0.0393122 |
| RAB1A | RAB1A, member RAS oncogene family | 0.039252 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0375664 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0372209 |
| RPL7 | ribosomal protein L7 | 0.0360066 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0359883 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0335457 |
| RPS19 | ribosomal protein S19 | 0.0309849 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0297387 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0272371 |
| RPLP1 | ribosomal protein, large, P1 | 0.026026 |
| CALR | calreticulin | 0.0258475 |
| TPI1 | triosephosphate isomerase 1 | 0.0238304 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0231935 |
| RTN4 | reticulon 4 | 0.0231817 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0209538 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0207883 |
| PDE8A | phosphodiesterase 8A | 0.0191244 |
| HLA-B | major histocompatibility complex, class I, B | 0.0189323 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0188067 |
| EZR | ezrin | 0.0187106 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0187026 |
| RBM33 | RNA binding motif protein 33 | 0.0183491 |
| RPL23 | ribosomal protein L23 | 0.0180262 |
| EFNA5 | ephrin-A5 | 0.0178853 |
| HELZ | helicase with zinc finger | 0.0175751 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0174519 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0168132 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0155714 |
| RPL9 | ribosomal protein L9 | 0.0136341 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.012776 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0120952 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.01175 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00847951 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00811912 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.00805059 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0070386 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00643524 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00616919 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00606519 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00451276 |
| RPLP2 | ribosomal protein, large, P2 | 0.00401842 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00279784 |
| PRKCA | protein kinase C, alpha | 0.00234301 |
| CANX | calnexin | 0.00174449 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00167694 |
| TMSB10 | thymosin beta 10 | 0.00107079 |
| MKI67 | marker of proliferation Ki-67 | 3.97394E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183466 |
| EGFR | epidermal growth factor receptor | -0.166506 |
| MT2A | metallothionein 2A | -0.145168 |
| HMGA2 | high mobility group AT-hook 2 | -0.128503 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.103811 |
| MYO1E | myosin IE | -0.102718 |
| TPM4 | tropomyosin 4 | -0.102384 |
| MYO6 | myosin VI | -0.0941439 |
| LDHA | lactate dehydrogenase A | -0.0940586 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0927459 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0824564 |
| RPS8 | ribosomal protein S8 | -0.0824206 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0809854 |
| PDE10A | phosphodiesterase 10A | -0.0808113 |
| NAV2 | neuron navigator 2 | -0.0808015 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0768302 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0760878 |
| COL5A1 | collagen, type V, alpha 1 | -0.0740339 |
| CDH13 | cadherin 13 | -0.0733383 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0728086 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0697322 |
| ANXA2 | annexin A2 | -0.0692263 |
| RUNX1 | runt-related transcription factor 1 | -0.0678249 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0673188 |
| HDAC9 | histone deacetylase 9 | -0.0664982 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0640346 |
| RPS3 | ribosomal protein S3 | -0.0631063 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0616817 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.060693 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0602308 |
| SLTM | SAFB-like, transcription modulator | -0.0601617 |
| MYOF | myoferlin | -0.0588165 |
| RPL12 | ribosomal protein L12 | -0.058419 |
| RPS12 | ribosomal protein S12 | -0.0567117 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0516963 |
| RPL34 | ribosomal protein L34 | -0.0511485 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0507583 |
| PTMA | prothymosin, alpha | -0.0500291 |
| PKM | pyruvate kinase, muscle | -0.0497206 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0490562 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0488732 |
| DST | dystonin | -0.0487571 |
| RPS23 | ribosomal protein S23 | -0.0479077 |
| SMYD3 | SET and MYND domain containing 3 | -0.0472078 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0467294 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0458574 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0437883 |
| IGF2 | insulin-like growth factor 2 | -0.043712 |
| PARD3 | par-3 family cell polarity regulator | -0.0427184 |
| NDRG1 | N-myc downstream regulated 1 | -0.0420773 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0408287 |
| USP34 | ubiquitin specific peptidase 34 | -0.0406717 |
| RPS6 | ribosomal protein S6 | -0.0393993 |
| ASPH | aspartate beta-hydroxylase | -0.0387853 |
| MAP4 | microtubule-associated protein 4 | -0.0369908 |
| ENO1 | enolase 1, (alpha) | -0.0362009 |
| MORF4L2 | mortality factor 4 like 2 | -0.0342635 |
| FTL | ferritin, light polypeptide | -0.034166 |
| POTEF | POTE ankyrin domain family, member F | -0.0338664 |
| B2M | beta-2-microglobulin | -0.0335001 |
| RPL37A | ribosomal protein L37a | -0.0327746 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0322612 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0307623 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0304847 |
| RPS25 | ribosomal protein S25 | -0.0301687 |
| ARRDC3 | arrestin domain containing 3 | -0.0300709 |
| YBX3 | Y box binding protein 3 | -0.0296867 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0284834 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.028333 |
| FMNL2 | formin-like 2 | -0.0274319 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0265543 |
| CUL3 | cullin 3 | -0.0265417 |
| MCL1 | myeloid cell leukemia 1 | -0.0262248 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0258454 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0255362 |
| UVRAG | UV radiation resistance associated | -0.0240649 |
| LAMB3 | laminin, beta 3 | -0.0240466 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0239377 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0235165 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0201723 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0188488 |
| COPA | coatomer protein complex, subunit alpha | -0.0188188 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0187184 |
| PCBP2 | poly(rC) binding protein 2 | -0.0181578 |
| RPL31 | ribosomal protein L31 | -0.0168031 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.016726 |
| FAM13A | family with sequence similarity 13, member A | -0.0161502 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0150657 |
| DIAPH2 | diaphanous-related formin 2 | -0.0146167 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0143936 |
| VIM | vimentin | -0.0131459 |
| VCL | vinculin | -0.0130107 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0113547 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0106618 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00834963 |
| RPL19 | ribosomal protein L19 | -0.00830522 |
| SBF2 | SET binding factor 2 | -0.00782397 |
| SRPK2 | SRSF protein kinase 2 | -0.00752381 |
| MED13L | mediator complex subunit 13-like | -0.00647103 |
| CD44 | CD44 molecule (Indian blood group) | -0.00629271 |
