| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | 0.0967335 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0852509 |
| DST | dystonin | 0.0850695 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0671363 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0642431 |
| HDAC9 | histone deacetylase 9 | 0.0627256 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0562276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0557936 |
| SPAG9 | sperm associated antigen 9 | 0.0549414 |
| MYO10 | myosin X | 0.0548892 |
| APP | amyloid beta (A4) precursor protein | 0.0530233 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.051655 |
| MB21D2 | Mab-21 domain containing 2 | 0.0510415 |
| FBXO11 | F-box protein 11 | 0.0492285 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0479659 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0473583 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0421507 |
| WDR43 | WD repeat domain 43 | 0.0421504 |
| RBM20 | RNA binding motif protein 20 | 0.0416548 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0414777 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0414169 |
| QKI | QKI, KH domain containing, RNA binding | 0.0400971 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0398044 |
| NCKAP1 | NCK-associated protein 1 | 0.0394491 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0387327 |
| RPL3 | ribosomal protein L3 | 0.03789 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0370133 |
| FUS | FUS RNA binding protein | 0.0363342 |
| CFL2 | cofilin 2 (muscle) | 0.035973 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0354519 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0353563 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0353183 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0352935 |
| NONO | non-POU domain containing, octamer-binding | 0.0349688 |
| SET | SET nuclear proto-oncogene | 0.0343579 |
| MED13L | mediator complex subunit 13-like | 0.0343352 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0343338 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0343201 |
| YAP1 | Yes-associated protein 1 | 0.0342516 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0341087 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0336369 |
| ENAH | enabled homolog (Drosophila) | 0.0335989 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.03348 |
| ITGAV | integrin, alpha V | 0.0319277 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0315234 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0314699 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0308269 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.030538 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0300254 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0296156 |
| VMP1 | vacuole membrane protein 1 | 0.0295779 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0294225 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0292603 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0291741 |
| ANXA5 | annexin A5 | 0.0288655 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0288076 |
| TPM3 | tropomyosin 3 | 0.0283995 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.028261 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0279225 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0279203 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0278898 |
| GAB2 | GRB2-associated binding protein 2 | 0.0278091 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0277551 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0277318 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0277133 |
| SIK3 | SIK family kinase 3 | 0.0276458 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0276121 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0271809 |
| SRP54 | signal recognition particle 54kDa | 0.0268769 |
| VEGFA | vascular endothelial growth factor A | 0.0268627 |
| SYT1 | synaptotagmin I | 0.0266567 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0261481 |
| PNN | pinin, desmosome associated protein | 0.0256486 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0255069 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0252326 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0249118 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.0248352 |
| RBM33 | RNA binding motif protein 33 | 0.0246497 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0245966 |
| CALR | calreticulin | 0.0244379 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0244035 |
| KIF1B | kinesin family member 1B | 0.0234754 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0233691 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0230793 |
| DLX2 | distal-less homeobox 2 | 0.0230146 |
| H1-0 | H1.0 linker histone | 0.022788 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0227297 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0227086 |
| DCTN1 | dynactin 1 | 0.0226041 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0225685 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.022336 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0222479 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0221908 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0221697 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0220668 |
| MSN | moesin | 0.0220562 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0220319 |
| AFAP1 | actin filament associated protein 1 | 0.0220196 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0219263 |
| WDR62 | WD repeat domain 62 | 0.0218907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.136955 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.12516 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.123408 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.119625 |
| PCDH9 | protocadherin 9 | -0.105263 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.104468 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10335 |
| COL11A1 | collagen, type XI, alpha 1 | -0.103112 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.084218 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0802144 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0800319 |
| RPLP1 | ribosomal protein, large, P1 | -0.079578 |
| GPC3 | glypican 3 | -0.0764744 |
| TMSB10 | thymosin beta 10 | -0.0755761 |
| PEG10 | paternally expressed 10 | -0.0677881 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0625553 |
| GNAS | GNAS complex locus | -0.0612679 |
| MEIS2 | Meis homeobox 2 | -0.0590408 |
| RPS16 | ribosomal protein S16 | -0.0561327 |
| ACTG1 | actin gamma 1 | -0.0543061 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0519789 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0512958 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0504122 |
| CADM2 | cell adhesion molecule 2 | -0.0493621 |
| DEK | DEK proto-oncogene | -0.047116 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0456579 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0446302 |
| RPS6 | ribosomal protein S6 | -0.0435781 |
| CENPF | centromere protein F, 350/400kDa | -0.0435308 |
| MKI67 | marker of proliferation Ki-67 | -0.0422472 |
| COL3A1 | collagen, type III, alpha 1 | -0.0419532 |
| RPS8 | ribosomal protein S8 | -0.0413268 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0395814 |
| CDH19 | cadherin 19, type 2 | -0.0393481 |
| RPS24 | ribosomal protein S24 | -0.0381911 |
| DPYD | dihydropyrimidine dehydrogenase | -0.036416 |
| RPL11 | ribosomal protein L11 | -0.0360453 |
| RBM25 | RNA binding motif protein 25 | -0.0357822 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0356681 |
| HMGB1 | high mobility group box 1 | -0.0356493 |
| METAP2 | methionyl aminopeptidase 2 | -0.0349521 |
| RPS19 | ribosomal protein S19 | -0.0348952 |
| FTL | ferritin, light polypeptide | -0.0343559 |
| RPL19 | ribosomal protein L19 | -0.0340962 |
| PRDX1 | peroxiredoxin 1 | -0.0339801 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.033433 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.03332 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0327832 |
| PTMA | prothymosin, alpha | -0.0325519 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0322494 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0322277 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0320423 |
| MTDH | metadherin | -0.0319182 |
| FOXP2 | forkhead box P2 | -0.0314184 |
| CAVIN1 | caveolae associated protein 1 | -0.0300654 |
| PRKD1 | protein kinase D1 | -0.0295222 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0294669 |
| GOLGA4 | golgin A4 | -0.029458 |
| COL1A2 | collagen, type I, alpha 2 | -0.0292467 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0290837 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0288904 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0288052 |
| TUT4 | terminal uridylyl transferase 4 | -0.0287517 |
| WASF2 | WAS protein family, member 2 | -0.0283077 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0283021 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0282766 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0275423 |
| RPL12 | ribosomal protein L12 | -0.0274506 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0273439 |
| ZFR | zinc finger RNA binding protein | -0.026988 |
| RTN3 | reticulon 3 | -0.026862 |
| RFPL4B | ret finger protein-like 4B | -0.0266976 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0264473 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0264374 |
| SNX6 | sorting nexin 6 | -0.0261897 |
| KNL1 | kinetochore scaffold 1 | -0.0260245 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0257945 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0256224 |
| NOP58 | NOP58 ribonucleoprotein | -0.0256143 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0253733 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0252672 |
| UBB | ubiquitin B | -0.0249933 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0248487 |
| NDRG1 | N-myc downstream regulated 1 | -0.0246099 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0243716 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0243485 |
| TPR | translocated promoter region, nuclear basket protein | -0.0243091 |
| RPS21 | ribosomal protein S21 | -0.0240929 |
| RPS2 | ribosomal protein S2 | -0.0239562 |
| RPL8 | ribosomal protein L8 | -0.0239516 |
| GPATCH8 | G patch domain containing 8 | -0.0239115 |
| CDK12 | cyclin-dependent kinase 12 | -0.0238993 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0238576 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0236369 |
| CAPNS1 | calpain, small subunit 1 | -0.0234753 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0234578 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0234269 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0234087 |
| BSG | basigin (Ok blood group) | -0.0233545 |
| SSH2 | slingshot protein phosphatase 2 | -0.0231599 |
