| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0887489 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0607768 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0593597 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0559283 |
| PLEC | plectin | 0.0493616 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.04853 |
| SFTPA2 | surfactant protein A2 | 0.0398811 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0368171 |
| SEPTIN9 | septin 9 | 0.034105 |
| EGR1 | early growth response 1 | 0.032491 |
| ADM | adrenomedullin | 0.03175 |
| RPLP0 | ribosomal protein, large, P0 | 0.0311042 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0308018 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.030299 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0285602 |
| NUP58 | nucleoporin 58 | 0.0271689 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0269288 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0268518 |
| VEGFA | vascular endothelial growth factor A | 0.0267517 |
| SPAG9 | sperm associated antigen 9 | 0.0257009 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0251228 |
| FOSL1 | FOS-like antigen 1 | 0.0248456 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.024001 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0225729 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0225405 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0221655 |
| FBL | fibrillarin | 0.0219676 |
| HPCAL1 | hippocalcin-like 1 | 0.0218379 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.021262 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0206406 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0204221 |
| ZFP36 | ZFP36 ring finger protein | 0.0202501 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0196045 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0195411 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0193913 |
| ARRDC3 | arrestin domain containing 3 | 0.019234 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0191232 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0190225 |
| MLF1 | myeloid leukemia factor 1 | 0.0190206 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0188438 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0187612 |
| SNX14 | sorting nexin 14 | 0.0186226 |
| COPA | coatomer protein complex, subunit alpha | 0.0185863 |
| STC2 | stanniocalcin 2 | 0.018563 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0176834 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0172214 |
| KLF6 | Kruppel-like factor 6 | 0.0172179 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0170346 |
| EPHA2 | EPH receptor A2 | 0.0169177 |
| ANLN | anillin, actin binding protein | 0.0168354 |
| SUCO | SUN domain containing ossification factor | 0.0167877 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0164576 |
| H1-0 | H1.0 linker histone | 0.0164572 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.016452 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0164206 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0162673 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0159114 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0158635 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0158077 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0157878 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0157832 |
| SRP54 | signal recognition particle 54kDa | 0.0153806 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.015311 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0150957 |
| NONO | non-POU domain containing, octamer-binding | 0.0149831 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.014885 |
| WDR45B | WD repeat domain 45B | 0.0147762 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0146151 |
| RPL3 | ribosomal protein L3 | 0.0140889 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0140833 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0140494 |
| TFRC | transferrin receptor | 0.0140059 |
| USP36 | ubiquitin specific peptidase 36 | 0.0139574 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0138068 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0137228 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.013432 |
| GOLGA4 | golgin A4 | 0.0134192 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0132655 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0132596 |
| SEC24A | SEC24 family member A | 0.0132029 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0129788 |
| CRY1 | cryptochrome circadian clock 1 | 0.0129478 |
| CUL4B | cullin 4B | 0.0127334 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0126925 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.012692 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.012535 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0125145 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0124103 |
| FMNL2 | formin-like 2 | 0.0123996 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0122682 |
| NDRG1 | N-myc downstream regulated 1 | 0.0122159 |
| WDR43 | WD repeat domain 43 | 0.0121929 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.0121578 |
| RLF | rearranged L-myc fusion | 0.0121449 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0120945 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0118692 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0117459 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0117414 |
| TLE3 | transducin-like enhancer of split 3 | 0.0115218 |
| TMEM39A | transmembrane protein 39A | 0.0114902 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.268858 |
| RPS16 | ribosomal protein S16 | -0.218406 |
| AHNAK | AHNAK nucleoprotein | -0.155568 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.136035 |
| UBC | ubiquitin C | -0.134435 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0953592 |
| TMSB10 | thymosin beta 10 | -0.0929596 |
| ENO1 | enolase 1, (alpha) | -0.0922208 |
| RPS27A | ribosomal protein S27a | -0.0860746 |
| ACTN4 | actinin, alpha 4 | -0.0722356 |
| ASPH | aspartate beta-hydroxylase | -0.0691628 |
| RPLP2 | ribosomal protein, large, P2 | -0.0665912 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0631759 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0628208 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.06214 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0605619 |
| VCL | vinculin | -0.0591749 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0551275 |
| RPLP1 | ribosomal protein, large, P1 | -0.0514861 |
| CD44 | CD44 molecule (Indian blood group) | -0.050692 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0498049 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0479115 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0475852 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0475486 |
| RTN4 | reticulon 4 | -0.0474108 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0473275 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0448999 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0410919 |
| FNDC3B | fibronectin type III domain containing 3B | -0.040989 |
| PCBP2 | poly(rC) binding protein 2 | -0.0396624 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0395718 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0394487 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0389538 |
| PTK2 | protein tyrosine kinase 2 | -0.0385682 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.038016 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0375973 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0359217 |
| RPS24 | ribosomal protein S24 | -0.035293 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0347984 |
| DST | dystonin | -0.0345558 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0339055 |
| RPS3 | ribosomal protein S3 | -0.0335501 |
| RPL37A | ribosomal protein L37a | -0.0333772 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0322785 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0314867 |
| SMYD3 | SET and MYND domain containing 3 | -0.0312652 |
| PKM | pyruvate kinase, muscle | -0.0311732 |
| RPL23 | ribosomal protein L23 | -0.0310656 |
| RPS12 | ribosomal protein S12 | -0.0306858 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0301811 |
| RPS8 | ribosomal protein S8 | -0.0298056 |
| PTMA | prothymosin, alpha | -0.0297942 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0295476 |
| MT2A | metallothionein 2A | -0.029045 |
| LDHA | lactate dehydrogenase A | -0.0287588 |
| EHBP1 | EH domain binding protein 1 | -0.0283979 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0281247 |
| PHF14 | PHD finger protein 14 | -0.0280874 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0275725 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0272438 |
| CDCP1 | CUB domain containing protein 1 | -0.0269942 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0265304 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0264241 |
| EFNA5 | ephrin-A5 | -0.0260122 |
| VMP1 | vacuole membrane protein 1 | -0.0259787 |
| DEK | DEK proto-oncogene | -0.0259525 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0257285 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0255992 |
| MCL1 | myeloid cell leukemia 1 | -0.025578 |
| RPL4 | ribosomal protein L4 | -0.0255613 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.025424 |
| IPO7 | importin 7 | -0.0250803 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0248829 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0246004 |
| RPS17 | ribosomal protein S17 | -0.0245946 |
| EGFR | epidermal growth factor receptor | -0.0245925 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0245835 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0244678 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0240592 |
| HMGA2 | high mobility group AT-hook 2 | -0.0239701 |
| S100A6 | S100 calcium binding protein A6 | -0.0238273 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0237112 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0236412 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0233641 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0230837 |
| DSTN | destrin (actin depolymerizing factor) | -0.0230005 |
| EXOC4 | exocyst complex component 4 | -0.0229859 |
| NF1 | neurofibromin 1 | -0.0226763 |
| RPS25 | ribosomal protein S25 | -0.0226102 |
| RPL28 | ribosomal protein L28 | -0.0226052 |
| OSMR | oncostatin M receptor | -0.0225859 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0225234 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.022473 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0224551 |
| SATB2 | SATB homeobox 2 | -0.022406 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0223941 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0223205 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0222753 |
| RPL26 | ribosomal protein L26 | -0.0222524 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0222193 |
