| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.25556 |
| VGF | VGF nerve growth factor inducible | 0.0806997 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0608865 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0574022 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0501566 |
| CENPF | centromere protein F, 350/400kDa | 0.0497263 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0448964 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.041725 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0397483 |
| LOC112694756 | uncharaterized LOC112694756 | 0.039699 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0379971 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0363827 |
| VEGFA | vascular endothelial growth factor A | 0.0361634 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0352536 |
| PTMA | prothymosin, alpha | 0.0351336 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0334317 |
| FAT1 | FAT atypical cadherin 1 | 0.0328968 |
| NCOR1 | nuclear receptor corepressor 1 | 0.032523 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0315183 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0313107 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0308113 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0306223 |
| MATR3 | matrin 3 | 0.0301339 |
| MKI67 | marker of proliferation Ki-67 | 0.0281636 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0271792 |
| SET | SET nuclear proto-oncogene | 0.0269858 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0261666 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0259076 |
| INHBA | inhibin, beta A | 0.0253976 |
| PNN | pinin, desmosome associated protein | 0.0250731 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0250545 |
| NUP58 | nucleoporin 58 | 0.0244812 |
| PCM1 | pericentriolar material 1 | 0.0243797 |
| NFIA | nuclear factor I/A | 0.0241478 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0241257 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0238733 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0236227 |
| NCKAP1 | NCK-associated protein 1 | 0.0236019 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0235103 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.023416 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0231493 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0229654 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0229242 |
| FOXN3 | forkhead box N3 | 0.0229157 |
| XPO1 | exportin 1 | 0.0228998 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0228175 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0227125 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0226642 |
| TPM3 | tropomyosin 3 | 0.0225017 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0223116 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0222067 |
| SETD5 | SET domain containing 5 | 0.0220739 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0220118 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0219368 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0218673 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0218531 |
| KIF1A | kinesin family member 1A | 0.0218526 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0218407 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0217786 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0217346 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0209617 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0207063 |
| HMGB2 | high mobility group box 2 | 0.0206639 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0204126 |
| EXOC5 | exocyst complex component 5 | 0.0203378 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0201924 |
| RPL3 | ribosomal protein L3 | 0.0201484 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0198996 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0194446 |
| MED13L | mediator complex subunit 13-like | 0.0194109 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0193996 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0193468 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0193426 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0189619 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0189184 |
| SARS1 | seryl-tRNA synthetase 1 | 0.0188949 |
| YY1AP1 | YY1 associated protein 1 | 0.0185011 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0184715 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0184159 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0183459 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0181099 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0180717 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0180479 |
| TXNIP | thioredoxin interacting protein | 0.0178876 |
| TPX2 | TPX2, microtubule-associated | 0.017848 |
| NONO | non-POU domain containing, octamer-binding | 0.0177596 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0177369 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0176944 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0176524 |
| SPAG5 | sperm associated antigen 5 | 0.0176286 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0176138 |
| CDCA2 | cell division cycle associated 2 | 0.0175048 |
| SLC35F4 | solute carrier family 35, member F4 | 0.017488 |
| XPOT | exportin, tRNA | 0.0174347 |
| MYEF2 | myelin expression factor 2 | 0.0174342 |
| RPL7 | ribosomal protein L7 | 0.0173786 |
| NKTR | natural killer cell triggering receptor | 0.0173218 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0170776 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0170644 |
| RACK1 | receptor for activated C kinase 1 | 0.0170367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.183635 |
| NRG1 | neuregulin 1 | -0.165681 |
| GPC6 | glypican 6 | -0.123801 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.108291 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0969097 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0944867 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0933157 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0871182 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0817568 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0792381 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0779569 |
| RORA | RAR-related orphan receptor A | -0.0712983 |
| ESRRG | estrogen-related receptor gamma | -0.0711369 |
| GPC5 | glypican 5 | -0.0693349 |
| SNTG1 | syntrophin, gamma 1 | -0.065067 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0640416 |
| SMYD3 | SET and MYND domain containing 3 | -0.0614581 |
| CNKSR3 | CNKSR family member 3 | -0.0591908 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0538762 |
| KIF26B | kinesin family member 26B | -0.0523725 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0520124 |
| SCG2 | secretogranin II | -0.0494653 |
| PTCHD4 | patched domain containing 4 | -0.0474955 |
| EFNA5 | ephrin-A5 | -0.0472589 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0471112 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0466835 |
| LSAMP | limbic system-associated membrane protein | -0.0461184 |
| NCKAP5 | NCK-associated protein 5 | -0.0461045 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0455625 |
| RNF213 | ring finger protein 213 | -0.0454095 |
| ACTG1 | actin gamma 1 | -0.0453253 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0451025 |
| FGF14 | fibroblast growth factor 14 | -0.0442508 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0438816 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0432687 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0427819 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0425552 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0422125 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0397539 |
| TOX | thymocyte selection-associated high mobility group box | -0.0395804 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0391414 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0383904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0375124 |
| NELL1 | NEL-like 1 (chicken) | -0.0371132 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0355927 |
| SYT1 | synaptotagmin I | -0.0348545 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0347812 |
| MCL1 | myeloid cell leukemia 1 | -0.0322633 |
| RIT2 | Ras-like without CAAX 2 | -0.0321228 |
| RALYL | RALY RNA binding protein-like | -0.0318195 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0309968 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0309825 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0307499 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0303612 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0291838 |
| RIGI | RNA sensor RIG-I | -0.0290297 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286454 |
| WWOX | WW domain containing oxidoreductase | -0.0283529 |
| ZNF804A | zinc finger protein 804A | -0.0279748 |
| CHGA | chromogranin A | -0.0275493 |
| ENO1 | enolase 1, (alpha) | -0.0274027 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.0272134 |
| SP100 | SP100 nuclear antigen | -0.0270467 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0270266 |
| NBEA | neurobeachin | -0.0264902 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0264491 |
| NDRG1 | N-myc downstream regulated 1 | -0.0262845 |
| MYT1L | myelin transcription factor 1-like | -0.0261349 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0259491 |
| LRFN2 | leucine rich repeat and fibronectin type III domain containing 2 | -0.0254626 |
| PCDH9 | protocadherin 9 | -0.02498 |
| STC1 | stanniocalcin 1 | -0.0246878 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0246301 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0246195 |
| ASPH | aspartate beta-hydroxylase | -0.0243964 |
| NAV2 | neuron navigator 2 | -0.0242982 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | -0.023972 |
| EPHA6 | EPH receptor A6 | -0.0237644 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.023464 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0233389 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0232459 |
| MMP26 | matrix metallopeptidase 26 | -0.0231717 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0231269 |
| EXOC4 | exocyst complex component 4 | -0.0230454 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0229797 |
| NLGN1 | neuroligin 1 | -0.022784 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0226544 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | -0.0224049 |
| MACROD2 | MACRO domain containing 2 | -0.0223669 |
| DTNA | dystrobrevin, alpha | -0.0216346 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0216026 |
| TRIM9 | tripartite motif containing 9 | -0.0215563 |
| FHIT | fragile histidine triad | -0.0215373 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0215016 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0211896 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0211589 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | -0.0209782 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0208291 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0207793 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0205629 |
