| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.136088 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.11368 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0751886 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0725454 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0618661 |
| FLNA | filamin A, alpha | 0.0608623 |
| PLEC | plectin | 0.0569187 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0527909 |
| PRELID2 | PRELI domain containing 2 | 0.0520988 |
| SFTPA2 | surfactant protein A2 | 0.0516698 |
| SQSTM1 | sequestosome 1 | 0.0514432 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0510296 |
| SPAG9 | sperm associated antigen 9 | 0.0487851 |
| CTTN | cortactin | 0.0472131 |
| MSI2 | musashi RNA-binding protein 2 | 0.0463725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0428404 |
| ANGPTL4 | angiopoietin-like 4 | 0.0428075 |
| NDRG1 | N-myc downstream regulated 1 | 0.0416279 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0404921 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0384323 |
| CANX | calnexin | 0.0380991 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.036661 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0365032 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0356993 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0356658 |
| CEP250 | centrosomal protein 250kDa | 0.0353298 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0352763 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0352288 |
| OGA | O-GlcNAcase | 0.0348587 |
| VIM | vimentin | 0.0348509 |
| ASPH | aspartate beta-hydroxylase | 0.0346139 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0345894 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0342602 |
| MMP12 | matrix metallopeptidase 12 | 0.0337392 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0336539 |
| TPM3 | tropomyosin 3 | 0.0336219 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0335899 |
| SEPTIN9 | septin 9 | 0.0331395 |
| STK10 | serine/threonine kinase 10 | 0.032919 |
| FMNL2 | formin-like 2 | 0.0327709 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0322318 |
| VEGFA | vascular endothelial growth factor A | 0.0318854 |
| MORF4L2 | mortality factor 4 like 2 | 0.0313991 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0310712 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0309382 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0305514 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0305358 |
| NGLY1 | N-glycanase 1 | 0.0303355 |
| EP300 | E1A binding protein p300 | 0.0301036 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0296883 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0293424 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0289713 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0287433 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0286432 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0279288 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0279168 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0277766 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0273945 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0273648 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0271723 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0270453 |
| CTBP2 | C-terminal binding protein 2 | 0.026985 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0265073 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0263479 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0262907 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0258115 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0256186 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0255331 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0254762 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0254069 |
| WDR45B | WD repeat domain 45B | 0.0252526 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0251942 |
| ANK2 | ankyrin 2, neuronal | 0.0245642 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0244153 |
| NAV2 | neuron navigator 2 | 0.0241229 |
| CFDP1 | craniofacial development protein 1 | 0.0241091 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0240625 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0239537 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0237676 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0237558 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0235196 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0234867 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0232333 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230443 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0226669 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0226015 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0224045 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0222467 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0221656 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.02208 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0219599 |
| RPS3 | ribosomal protein S3 | 0.021931 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0219114 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0218934 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0217957 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0217767 |
| ARRDC3 | arrestin domain containing 3 | 0.0216803 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.02153 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0214627 |
| TMEM51 | transmembrane protein 51 | 0.0214532 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.183869 |
| FN1 | fibronectin 1 | -0.113246 |
| FMN1 | formin 1 | -0.104298 |
| FRMD5 | FERM domain containing 5 | -0.0950241 |
| CCND1 | cyclin D1 | -0.0790153 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0549042 |
| CDK6 | cyclin-dependent kinase 6 | -0.0531242 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0519928 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0496273 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0408399 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0405976 |
| POTEF | POTE ankyrin domain family, member F | -0.0390641 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0376062 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0352556 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0311172 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0307726 |
| RAD51B | RAD51 paralog B | -0.0300106 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0293635 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0290838 |
| FRMD4A | FERM domain containing 4A | -0.0289329 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0285805 |
| RUNX1 | runt-related transcription factor 1 | -0.0269696 |
| MACROD2 | MACRO domain containing 2 | -0.0262749 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0250092 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0245557 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0239439 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0238755 |
| TSC22D2 | TSC22 domain family, member 2 | -0.023335 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0227828 |
| RIGI | RNA sensor RIG-I | -0.0225798 |
| TXNRD1 | thioredoxin reductase 1 | -0.0221549 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0218651 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0218191 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.021786 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0215075 |
| PLSCR1 | phospholipid scramblase 1 | -0.0210246 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.020978 |
| PHF14 | PHD finger protein 14 | -0.0206363 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0204986 |
| BPTF | bromodomain PHD finger transcription factor | -0.0198921 |
| TMSB10 | thymosin beta 10 | -0.0196277 |
| RNF213 | ring finger protein 213 | -0.019567 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0195289 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0192698 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | -0.0192379 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0192114 |
| HMGA1 | high mobility group AT-hook 1 | -0.0189245 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0189045 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0188754 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0188602 |
| PMP22 | peripheral myelin protein 22 | -0.0188273 |
| CBX3 | chromobox homolog 3 | -0.0185837 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0185258 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0185053 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0184818 |
| EFNA5 | ephrin-A5 | -0.0184426 |
| ERBIN | erbb2 interacting protein | -0.0183511 |
| MTAP | methylthioadenosine phosphorylase | -0.0181406 |
| KIF5C | kinesin family member 5C | -0.0180534 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0179907 |
| RPS16 | ribosomal protein S16 | -0.0179576 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0178507 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0178406 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0178374 |
| SMYD3 | SET and MYND domain containing 3 | -0.0178227 |
| NRXN3 | neurexin 3 | -0.0177479 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0175102 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0170423 |
| FHIT | fragile histidine triad | -0.0170045 |
| ETV6 | ets variant 6 | -0.0169402 |
| RASAL2 | RAS protein activator like 2 | -0.0168034 |
| PRAME | preferentially expressed antigen in melanoma | -0.0167611 |
| PCNX4 | pecanex 4 | -0.0167139 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0166441 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0166316 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0163262 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0162552 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0162317 |
| FOXP1 | forkhead box P1 | -0.016169 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0158903 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0158558 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0157427 |
| CENPE | centromere protein E, 312kDa | -0.0154847 |
| IFI44L | interferon-induced protein 44-like | -0.0154619 |
| EHBP1 | EH domain binding protein 1 | -0.0152502 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0151944 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.015139 |
| ULK4 | unc-51 like kinase 4 | -0.0148959 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0148875 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0148327 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0146555 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0145399 |
| TCF12 | transcription factor 12 | -0.0145253 |
| COMMD10 | COMM domain containing 10 | -0.0144176 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0142481 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0142294 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0141482 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0141293 |
| DHFR | dihydrofolate reductase | -0.0140293 |
| SCFD2 | sec1 family domain containing 2 | -0.0139039 |
