| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.158472 |
| VEGFA | vascular endothelial growth factor A | 0.116161 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.108396 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.10205 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0981193 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0939448 |
| FN1 | fibronectin 1 | 0.0939229 |
| NAV2 | neuron navigator 2 | 0.0905317 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0856737 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.080821 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0743284 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0675155 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0647805 |
| ADM | adrenomedullin | 0.060425 |
| ARRDC3 | arrestin domain containing 3 | 0.0589263 |
| NDRG1 | N-myc downstream regulated 1 | 0.0544349 |
| OGA | O-GlcNAcase | 0.0509304 |
| MKI67 | marker of proliferation Ki-67 | 0.0494974 |
| SFTPA2 | surfactant protein A2 | 0.0478796 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0435963 |
| ATP13A3 | ATPase type 13A3 | 0.0422991 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0411915 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0404532 |
| ANLN | anillin, actin binding protein | 0.0403371 |
| SPAG9 | sperm associated antigen 9 | 0.0401375 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0401286 |
| B2M | beta-2-microglobulin | 0.0387739 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0382187 |
| GOLGA4 | golgin A4 | 0.0377446 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0376294 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0369501 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0366 |
| ZNF292 | zinc finger protein 292 | 0.0363578 |
| WTAP | Wilms tumor 1 associated protein | 0.0360469 |
| FLNB | filamin B, beta | 0.035807 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0353753 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0353497 |
| MSN | moesin | 0.0352009 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0349791 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0346823 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0339176 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0336376 |
| HELZ | helicase with zinc finger | 0.032944 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0328025 |
| NONO | non-POU domain containing, octamer-binding | 0.0324864 |
| CENPF | centromere protein F, 350/400kDa | 0.0322133 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0315364 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0312395 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.031203 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0306627 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0305957 |
| APP | amyloid beta (A4) precursor protein | 0.0301775 |
| KIF4A | kinesin family member 4A | 0.0300127 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0299381 |
| RPLP0 | ribosomal protein, large, P0 | 0.0298307 |
| STC1 | stanniocalcin 1 | 0.0294786 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.029236 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0292195 |
| CDK19 | cyclin-dependent kinase 19 | 0.0285655 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0283527 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0275274 |
| KLF6 | Kruppel-like factor 6 | 0.0272283 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0271373 |
| JMJD1C | jumonji domain containing 1C | 0.0266833 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0266321 |
| FLNA | filamin A, alpha | 0.0265852 |
| ANXA2 | annexin A2 | 0.0265735 |
| ICAM1 | intercellular adhesion molecule 1 | 0.026311 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0261406 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0260703 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0257546 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0257431 |
| FNIP1 | folliculin interacting protein 1 | 0.0257092 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0255346 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0252557 |
| DIAPH3 | diaphanous-related formin 3 | 0.0245359 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.024042 |
| DENND5A | DENN/MADD domain containing 5A | 0.0238434 |
| USP37 | ubiquitin specific peptidase 37 | 0.0237379 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0236377 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0234347 |
| COPA | coatomer protein complex, subunit alpha | 0.0228708 |
| TPX2 | TPX2, microtubule-associated | 0.0224079 |
| SNX9 | sorting nexin 9 | 0.0220417 |
| EZR | ezrin | 0.0219404 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0215726 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0212438 |
| FMNL2 | formin-like 2 | 0.0210808 |
| NGLY1 | N-glycanase 1 | 0.021054 |
| PTMA | prothymosin, alpha | 0.0207224 |
| MATR3 | matrin 3 | 0.0207062 |
| FOXO3 | forkhead box O3 | 0.0206444 |
| CEP250 | centrosomal protein 250kDa | 0.0205637 |
| PHIP | pleckstrin homology domain interacting protein | 0.0205576 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0204628 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0203904 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0203471 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0202711 |
| WDR45B | WD repeat domain 45B | 0.0201588 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201226 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.190094 |
| GLIS3 | GLIS family zinc finger 3 | -0.162889 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.136114 |
| HMGA2 | high mobility group AT-hook 2 | -0.0895641 |
| VCL | vinculin | -0.0756274 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0721263 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0713907 |
| EXT1 | exostosin glycosyltransferase 1 | -0.070768 |
| BICC1 | BicC family RNA binding protein 1 | -0.0679597 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.063126 |
| IER3 | immediate early response 3 | -0.0597001 |
| DST | dystonin | -0.0563553 |
| VCAN | versican | -0.0559694 |
| CDH13 | cadherin 13 | -0.0549405 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0495108 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0477748 |
| ASPH | aspartate beta-hydroxylase | -0.0455395 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0451749 |
| NAV1 | neuron navigator 1 | -0.044534 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0437816 |
| AHNAK | AHNAK nucleoprotein | -0.0433278 |
| RAI14 | retinoic acid induced 14 | -0.0423363 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0416356 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0407368 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0403187 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0395998 |
| TENM2 | teneurin transmembrane protein 2 | -0.0395206 |
| EGFR | epidermal growth factor receptor | -0.0383582 |
| NABP1 | nucleic acid binding protein 1 | -0.0373917 |
| TMSB10 | thymosin beta 10 | -0.0373784 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0373701 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0367177 |
| TPM1 | tropomyosin 1 (alpha) | -0.0347427 |
| DIAPH2 | diaphanous-related formin 2 | -0.0345557 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0343467 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0334574 |
| SLC35F3 | solute carrier family 35, member F3 | -0.033302 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0332519 |
| TNS3 | tensin 3 | -0.0323732 |
| GPC6 | glypican 6 | -0.0321646 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0319465 |
| TMEM132D | transmembrane protein 132D | -0.0314486 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0302291 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0298418 |
| EFNA5 | ephrin-A5 | -0.0295005 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0283984 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0282544 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0281935 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0279558 |
| FTL | ferritin, light polypeptide | -0.027621 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0275186 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.027117 |
| INTS6 | integrator complex subunit 6 | -0.0270094 |
| COL1A1 | collagen, type I, alpha 1 | -0.0269948 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265838 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0262142 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0259528 |
| NCKAP5 | NCK-associated protein 5 | -0.0257388 |
| CTSD | cathepsin D | -0.0255276 |
| RAD51B | RAD51 paralog B | -0.0253318 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0250692 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0248542 |
| UTRN | utrophin | -0.0242312 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.0239739 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0237789 |
| EHBP1 | EH domain binding protein 1 | -0.0235286 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0235172 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0234916 |
| LOX | lysyl oxidase | -0.0234652 |
| RNF213 | ring finger protein 213 | -0.0233895 |
| COL5A1 | collagen, type V, alpha 1 | -0.0224785 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0221932 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0216532 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.02154 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.021297 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0209274 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0209232 |
| BNC2 | basonuclin 2 | -0.0208648 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0207905 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0206919 |
| PRKCA | protein kinase C, alpha | -0.0202935 |
| SVIL | supervillin | -0.0201788 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0200721 |
| RRBP1 | ribosome binding protein 1 | -0.0199736 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0197641 |
| CNTN6 | contactin 6 | -0.0195162 |
| AUTS2 | autism susceptibility candidate 2 | -0.0194691 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0194592 |
| SMYD3 | SET and MYND domain containing 3 | -0.0194395 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0191462 |
| PRR16 | proline rich 16 | -0.0191267 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0189644 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0189581 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0187239 |
| WDR27 | WD repeat domain 27 | -0.0187027 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0184779 |
| EXOC4 | exocyst complex component 4 | -0.0181719 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0180792 |
| CLMP | CXADR-like membrane protein | -0.0177425 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.017728 |
