| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.323147 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.138717 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.108943 |
| VEGFA | vascular endothelial growth factor A | 0.0959412 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0858359 |
| NDRG1 | N-myc downstream regulated 1 | 0.0757354 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0674226 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0642437 |
| COPA | coatomer protein complex, subunit alpha | 0.0639919 |
| CDH13 | cadherin 13 | 0.0638553 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0619089 |
| B2M | beta-2-microglobulin | 0.0597553 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0586574 |
| SBF2 | SET binding factor 2 | 0.0572123 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0545961 |
| PLEC | plectin | 0.0534785 |
| COL5A1 | collagen, type V, alpha 1 | 0.0526374 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0518891 |
| TMEM165 | transmembrane protein 165 | 0.0510108 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0474983 |
| FN1 | fibronectin 1 | 0.0442741 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0441754 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0433706 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.043044 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0408214 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0403154 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0399651 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0396968 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0387694 |
| CD44 | CD44 molecule (Indian blood group) | 0.0384264 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0383646 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0378636 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.037703 |
| MSN | moesin | 0.0364635 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0363903 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0362988 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0362932 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0361634 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0358687 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0358156 |
| ATP13A3 | ATPase type 13A3 | 0.0355183 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0354806 |
| HMGA2 | high mobility group AT-hook 2 | 0.0346802 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0344727 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.0341802 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0341461 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0341429 |
| MMP12 | matrix metallopeptidase 12 | 0.0340211 |
| KAZN | kazrin, periplakin interacting protein | 0.0333131 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0332149 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0318815 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0315589 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.031278 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0311762 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0309469 |
| FUS | FUS RNA binding protein | 0.0309371 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0309071 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0308186 |
| STC2 | stanniocalcin 2 | 0.0307426 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0306391 |
| FLNA | filamin A, alpha | 0.0299029 |
| FNIP1 | folliculin interacting protein 1 | 0.0298061 |
| SMTN | smoothelin | 0.0297411 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0293103 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0288818 |
| SEPTIN9 | septin 9 | 0.028865 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0283648 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0282494 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0281707 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0279648 |
| PTGES2 | prostaglandin E synthase 2 | 0.0279441 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0276555 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0275978 |
| IL6 | interleukin 6 | 0.0275802 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0275723 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0275282 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0274861 |
| EGFR | epidermal growth factor receptor | 0.0270503 |
| SPAG9 | sperm associated antigen 9 | 0.0270497 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0268497 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0266618 |
| NPTN | neuroplastin | 0.026548 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0265328 |
| PRRC2B | proline-rich coiled-coil 2B | 0.026504 |
| FMNL2 | formin-like 2 | 0.0265004 |
| S100A10 | S100 calcium binding protein A10 | 0.0264637 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0263548 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0263485 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0262698 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0260979 |
| SEPTIN2 | septin 2 | 0.026052 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0259787 |
| ARRDC3 | arrestin domain containing 3 | 0.025867 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0258335 |
| RPS12 | ribosomal protein S12 | 0.0256655 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0256599 |
| ENO1 | enolase 1, (alpha) | 0.0255999 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0255017 |
| CLMP | CXADR-like membrane protein | 0.0251932 |
| SNX9 | sorting nexin 9 | 0.0251381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197305 |
| TMSB10 | thymosin beta 10 | -0.0704725 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0584505 |
| MT1X | metallothionein 1X | -0.0574879 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.049246 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0481195 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0421459 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0415169 |
| VCL | vinculin | -0.04028 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0364867 |
| SMAD3 | SMAD family member 3 | -0.0359239 |
| MT2A | metallothionein 2A | -0.0354025 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0353535 |
| S100A6 | S100 calcium binding protein A6 | -0.0350618 |
| RPS24 | ribosomal protein S24 | -0.03378 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0337399 |
| COL1A1 | collagen, type I, alpha 1 | -0.0331477 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0329868 |
| CCNI | cyclin I | -0.0328322 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0325996 |
| PALLD | palladin, cytoskeletal associated protein | -0.0324465 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0320587 |
| PCM1 | pericentriolar material 1 | -0.0318705 |
| S100A9 | S100 calcium binding protein A9 | -0.0314385 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0312504 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0309403 |
| CLINT1 | clathrin interactor 1 | -0.0308087 |
| GLIS3 | GLIS family zinc finger 3 | -0.0304174 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0294641 |
| CDK13 | cyclin-dependent kinase 13 | -0.0292921 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.028974 |
| LOX | lysyl oxidase | -0.0288379 |
| RPLP1 | ribosomal protein, large, P1 | -0.0284657 |
| RPS19 | ribosomal protein S19 | -0.0282474 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0281964 |
| DUSP6 | dual specificity phosphatase 6 | -0.0280893 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0280158 |
| SETBP1 | SET binding protein 1 | -0.0278764 |
| CALD1 | caldesmon 1 | -0.0277516 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0274911 |
| TPM4 | tropomyosin 4 | -0.0270521 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0269266 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0268455 |
| RPS5 | ribosomal protein S5 | -0.0266769 |
| RPL37 | ribosomal protein L37 | -0.0262036 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0261 |
| CDK6 | cyclin-dependent kinase 6 | -0.0260313 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0259026 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0254023 |
| NKTR | natural killer cell triggering receptor | -0.025115 |
| TXNIP | thioredoxin interacting protein | -0.0250983 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.024921 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0246802 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245813 |
| CDC73 | cell division cycle 73 | -0.0244977 |
| ENAH | enabled homolog (Drosophila) | -0.0244257 |
| UBC | ubiquitin C | -0.0244131 |
| ZNF292 | zinc finger protein 292 | -0.0243263 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0243145 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0238075 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0237176 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.023611 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0234961 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0234852 |
| H3-3B | H3.3 histone B | -0.0232504 |
| VMP1 | vacuole membrane protein 1 | -0.0231964 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0231306 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | -0.0229344 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0228987 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase | -0.0227315 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0225332 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0223234 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0223039 |
| FMN1 | formin 1 | -0.0222581 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0220229 |
| WBP11 | WW domain binding protein 11 | -0.0220163 |
| CFDP1 | craniofacial development protein 1 | -0.021826 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0217741 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0217189 |
| EFNA5 | ephrin-A5 | -0.0216107 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0215916 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0215631 |
| PURA | purine-rich element binding protein A | -0.0214713 |
| CERT1 | ceramide transporter 1 | -0.0213436 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0213173 |
| CLOCK | clock circadian regulator | -0.0212238 |
| PHKB | phosphorylase kinase, beta | -0.0212198 |
| STAG2 | stromal antigen 2 | -0.0211413 |
| RRBP1 | ribosome binding protein 1 | -0.0208137 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0207974 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.020655 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0205979 |
| FCHO2 | FCH domain only 2 | -0.0203144 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.0201425 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0200721 |
| DISC1 | disrupted in schizophrenia 1 | -0.0199705 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0198655 |
| TMEM14B | transmembrane protein 14B | -0.019812 |
| HMGB1 | high mobility group box 1 | -0.0197227 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0196523 |
