| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.125551 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.115325 |
| PRRC2C | proline-rich coiled-coil 2C | 0.112504 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0974228 |
| VEGFA | vascular endothelial growth factor A | 0.0917699 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0813982 |
| RNF145 | ring finger protein 145 | 0.0748707 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0711738 |
| AHR | aryl hydrocarbon receptor | 0.0673468 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0652397 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0628259 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0617006 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0600932 |
| MT2A | metallothionein 2A | 0.0581342 |
| ZNF292 | zinc finger protein 292 | 0.0566993 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0563422 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0544206 |
| COPA | coatomer protein complex, subunit alpha | 0.0530431 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0528832 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0527028 |
| TMEM156 | transmembrane protein 156 | 0.0524896 |
| MKI67 | marker of proliferation Ki-67 | 0.0522631 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0501178 |
| OGA | O-GlcNAcase | 0.0495388 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0493361 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0489956 |
| NUP58 | nucleoporin 58 | 0.0489837 |
| SMAD3 | SMAD family member 3 | 0.0479122 |
| FAT1 | FAT atypical cadherin 1 | 0.0470531 |
| PTK2 | protein tyrosine kinase 2 | 0.0470237 |
| RACK1 | receptor for activated C kinase 1 | 0.0464723 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0464344 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0461664 |
| CAB39 | calcium binding protein 39 | 0.0460289 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0457234 |
| GOLGA4 | golgin A4 | 0.0455753 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0452828 |
| NEK7 | NIMA-related kinase 7 | 0.0452551 |
| HELZ | helicase with zinc finger | 0.0452315 |
| TXNRD1 | thioredoxin reductase 1 | 0.0449486 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0449203 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0429656 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.042951 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0428559 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0418782 |
| FNBP1 | formin binding protein 1 | 0.0410772 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0404904 |
| OSMR | oncostatin M receptor | 0.0404318 |
| CD109 | CD109 molecule | 0.0396059 |
| APP | amyloid beta (A4) precursor protein | 0.0392976 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.037951 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.037549 |
| PELO | pelota homolog (Drosophila) | 0.0375153 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0374568 |
| CANX | calnexin | 0.0374269 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0374129 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0369755 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0368165 |
| FLNA | filamin A, alpha | 0.036529 |
| B2M | beta-2-microglobulin | 0.0364855 |
| NRP1 | neuropilin 1 | 0.0363138 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0361114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0360315 |
| FAM13A | family with sequence similarity 13, member A | 0.0356636 |
| TPM3 | tropomyosin 3 | 0.0354999 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0352701 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0352542 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0351326 |
| SEPTIN7 | septin 7 | 0.0351219 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0345886 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0343141 |
| CALR | calreticulin | 0.0339904 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0338332 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0338003 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.033457 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0330585 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0328451 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0328275 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0327947 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0327272 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0326861 |
| RUNX2 | runt-related transcription factor 2 | 0.0326624 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0321112 |
| HDGF | hepatoma-derived growth factor | 0.0318025 |
| YBX1 | Y box binding protein 1 | 0.0316103 |
| CD44 | CD44 molecule (Indian blood group) | 0.0312146 |
| SPAG9 | sperm associated antigen 9 | 0.0311388 |
| PNN | pinin, desmosome associated protein | 0.0310885 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0308027 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0306187 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0305415 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0304881 |
| TFG | TRK-fused gene | 0.0303153 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0300646 |
| RTN4 | reticulon 4 | 0.0299569 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0292637 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0290008 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0289962 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0289159 |
| CDC73 | cell division cycle 73 | 0.0289034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.22623 |
| FN1 | fibronectin 1 | -0.137203 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.126352 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.120242 |
| HMGA2 | high mobility group AT-hook 2 | -0.0842464 |
| INTS6 | integrator complex subunit 6 | -0.0796846 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0761378 |
| SQSTM1 | sequestosome 1 | -0.075846 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0694205 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0685925 |
| VCL | vinculin | -0.0648034 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.061167 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0609215 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0602175 |
| AEBP2 | AE binding protein 2 | -0.0581443 |
| EGR1 | early growth response 1 | -0.0474923 |
| IER3 | immediate early response 3 | -0.0474072 |
| LRRC23 | leucine rich repeat containing 23 | -0.0447669 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0447447 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0438117 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0436326 |
| PTMA | prothymosin, alpha | -0.0432381 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0427784 |
| TMSB10 | thymosin beta 10 | -0.0416651 |
| ACTG1 | actin gamma 1 | -0.0416413 |
| CADM1 | cell adhesion molecule 1 | -0.0402915 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0394495 |
| HLA-B | major histocompatibility complex, class I, B | -0.0393149 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0390065 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0380022 |
| RPS24 | ribosomal protein S24 | -0.0379243 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0373235 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0365593 |
| S100A6 | S100 calcium binding protein A6 | -0.0362733 |
| FTL | ferritin, light polypeptide | -0.0356739 |
| DUSP6 | dual specificity phosphatase 6 | -0.034761 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.034339 |
| RAI14 | retinoic acid induced 14 | -0.0342381 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0338919 |
| MCL1 | myeloid cell leukemia 1 | -0.033659 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0329137 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0324844 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0322635 |
| STC2 | stanniocalcin 2 | -0.0321714 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0320739 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0315574 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0309758 |
| PALLD | palladin, cytoskeletal associated protein | -0.0306849 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0305878 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0305428 |
| EFNA5 | ephrin-A5 | -0.0302533 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0297033 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0288861 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0288332 |
| SYT1 | synaptotagmin I | -0.0288004 |
| RPL31 | ribosomal protein L31 | -0.02854 |
| LOX | lysyl oxidase | -0.0280772 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0263283 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0259664 |
| CCDC138 | coiled-coil domain containing 138 | -0.0257602 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0257282 |
| CUX1 | cut-like homeobox 1 | -0.0255729 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0252269 |
| CTSD | cathepsin D | -0.025185 |
| SCFD2 | sec1 family domain containing 2 | -0.0245872 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0242248 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0241988 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0239471 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0237475 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0236878 |
| TENM4 | teneurin transmembrane protein 4 | -0.0236437 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0235269 |
| PRKCA | protein kinase C, alpha | -0.0234893 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0234313 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0233866 |
| FBN1 | fibrillin 1 | -0.0233663 |
| TMSB4X | thymosin beta 4, X-linked | -0.0231174 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.023076 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0230245 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0229523 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0228938 |
| VIM | vimentin | -0.0228666 |
| MYO1E | myosin IE | -0.0227885 |
| TUFT1 | tuftelin 1 | -0.0226483 |
| POU2F2 | POU class 2 homeobox 2 | -0.0219879 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0219553 |
| CDK13 | cyclin-dependent kinase 13 | -0.021893 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0218851 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0213843 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0212938 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0208792 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0207794 |
| NXN | nucleoredoxin | -0.0206062 |
| HLA-A | major histocompatibility complex, class I, A | -0.0204593 |
| UBC | ubiquitin C | -0.020397 |
| ARF4 | ADP-ribosylation factor 4 | -0.0202691 |
| EXOC4 | exocyst complex component 4 | -0.0201149 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.020073 |
| CLIC4 | chloride intracellular channel 4 | -0.0198778 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0194476 |
