| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cyclosporin A perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cyclosporin A_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.217509 |
| KRT8 | keratin 8, type II | 0.150027 |
| KRT18 | keratin 18, type I | 0.134647 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.106241 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0914138 |
| ANXA2 | annexin A2 | 0.0820119 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0817257 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0751774 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0745797 |
| PLEC | plectin | 0.0723967 |
| EZR | ezrin | 0.0706845 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0698163 |
| BCL2L1 | BCL2-like 1 | 0.0683697 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0680898 |
| FAT1 | FAT atypical cadherin 1 | 0.0667071 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0663467 |
| PTMA | prothymosin, alpha | 0.0639158 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0636392 |
| FLNA | filamin A, alpha | 0.0628292 |
| ACTN4 | actinin, alpha 4 | 0.0624879 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0597398 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0579049 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0556446 |
| EGR1 | early growth response 1 | 0.0545455 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0522891 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0497327 |
| TMSB4X | thymosin beta 4, X-linked | 0.0464862 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0442046 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.044107 |
| B2M | beta-2-microglobulin | 0.043894 |
| MED15 | mediator complex subunit 15 | 0.0435318 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0435297 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0432602 |
| NDRG1 | N-myc downstream regulated 1 | 0.043242 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0429387 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0419859 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0417534 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0406085 |
| SNX9 | sorting nexin 9 | 0.0405976 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0405723 |
| PKM | pyruvate kinase, muscle | 0.0394215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0389993 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0382959 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.037938 |
| CALR | calreticulin | 0.0376978 |
| VEGFA | vascular endothelial growth factor A | 0.0371548 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0363496 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0353621 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0352611 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0350096 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0342539 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0335708 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0329492 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0325118 |
| MYOF | myoferlin | 0.0324977 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0322096 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0321955 |
| AMOTL2 | angiomotin like 2 | 0.0315319 |
| ANXA11 | annexin A11 | 0.0315033 |
| H1-0 | H1.0 linker histone | 0.0305853 |
| JUP | junction plakoglobin | 0.0301897 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0300543 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0299989 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0295687 |
| SET | SET nuclear proto-oncogene | 0.0295393 |
| NONO | non-POU domain containing, octamer-binding | 0.0294657 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0294034 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0293892 |
| PERP | PERP, TP53 apoptosis effector | 0.0290987 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0289852 |
| APP | amyloid beta (A4) precursor protein | 0.0289224 |
| DSPP | dentin sialophosphoprotein | 0.0286143 |
| SQSTM1 | sequestosome 1 | 0.0283673 |
| MYO5B | myosin VB | 0.028338 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0278254 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0277473 |
| MKI67 | marker of proliferation Ki-67 | 0.0275531 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0275095 |
| FUS | FUS RNA binding protein | 0.0274806 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0273678 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0272874 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0270723 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0269268 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0267454 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.026737 |
| ANKRD11 | ankyrin repeat domain 11 | 0.02669 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0265404 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0264502 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0264406 |
| CTSA | cathepsin A | 0.0261877 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0261577 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0259388 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0259116 |
| OXSR1 | oxidative stress responsive 1 | 0.025865 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0258199 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0257751 |
| PLK2 | polo-like kinase 2 | 0.0257627 |
| POTEF | POTE ankyrin domain family, member F | 0.0257422 |
| ITGA6 | integrin, alpha 6 | 0.0257347 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0256288 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.03583 |
| RPS6 | ribosomal protein S6 | -0.0313101 |
| TMSB10 | thymosin beta 10 | -0.0287796 |
| RPS2 | ribosomal protein S2 | -0.0250531 |
| RPLP1 | ribosomal protein, large, P1 | -0.0227696 |
| IER3 | immediate early response 3 | -0.0182973 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0174597 |
| RPLP2 | ribosomal protein, large, P2 | -0.0173408 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0173232 |
| HMGB1 | high mobility group box 1 | -0.0170458 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0163595 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0152206 |
| RPL32 | ribosomal protein L32 | -0.0149263 |
| RPS19 | ribosomal protein S19 | -0.0148431 |
| RPL28 | ribosomal protein L28 | -0.0147011 |
| RPL12 | ribosomal protein L12 | -0.0145325 |
| RPS5 | ribosomal protein S5 | -0.0140645 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0139823 |
| RPL35A | ribosomal protein L35a | -0.0139058 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0138052 |
| RPL19 | ribosomal protein L19 | -0.012924 |
| SEPTIN7 | septin 7 | -0.0124815 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0122438 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.011714 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0115574 |
| RPS24 | ribosomal protein S24 | -0.0114553 |
| DACH1 | dachshund family transcription factor 1 | -0.0109677 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0109289 |
| DEK | DEK proto-oncogene | -0.0108388 |
| RIGI | RNA sensor RIG-I | -0.0106286 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0105572 |
| VIM | vimentin | -0.010289 |
| RPS11 | ribosomal protein S11 | -0.0102418 |
| RPL23A | ribosomal protein L23a | -0.0101415 |
| RPL7 | ribosomal protein L7 | -0.0100955 |
| NEMF | nuclear export mediator factor | -0.00978626 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.00977565 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.00958421 |
| RPS15 | ribosomal protein S15 | -0.00957152 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00952006 |
| USP3 | ubiquitin specific peptidase 3 | -0.00935153 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00920711 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.00915269 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00911603 |
| FAM76B | family with sequence similarity 76, member B | -0.00911311 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.00910272 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00892887 |
| RPL9 | ribosomal protein L9 | -0.00889457 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00887048 |
| RPL36 | ribosomal protein L36 | -0.00886645 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.00881532 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00872848 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00858438 |
| RNF149 | ring finger protein 149 | -0.00852002 |
| RPL38 | ribosomal protein L38 | -0.00845027 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.00840819 |
| RPS25 | ribosomal protein S25 | -0.00833815 |
| FNDC3A | fibronectin type III domain containing 3A | -0.00825656 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.00821648 |
| H1-4 | H1.4 linker histone, cluster member | -0.00820102 |
| RPL14 | ribosomal protein L14 | -0.00819102 |
| NHSL1 | NHS-like 1 | -0.00808879 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0080563 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.00795982 |
| HBP1 | HMG-box transcription factor 1 | -0.00790988 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0077792 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.00774835 |
| RNF13 | ring finger protein 13 | -0.0076713 |
| RPL31 | ribosomal protein L31 | -0.00759197 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0075458 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.00753065 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.00749032 |
| SELENOT | selenoprotein T | -0.00745779 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.00745588 |
| MX2 | MX dynamin-like GTPase 2 | -0.00744058 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.00743415 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.00741154 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.00740841 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.00720254 |
| MYO9A | myosin IXA | -0.00717379 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.00711399 |
| CCDC91 | coiled-coil domain containing 91 | -0.00710876 |
| RPL4 | ribosomal protein L4 | -0.00706722 |
| NKTR | natural killer cell triggering receptor | -0.00706563 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0070289 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.00696913 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00695118 |
| SSR4 | signal sequence receptor, delta | -0.00694943 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.00690671 |
| GPSM2 | G-protein signaling modulator 2 | -0.00687905 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.00687749 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0068522 |
| CENPF | centromere protein F, 350/400kDa | -0.00679473 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00678713 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00676498 |
| GPHN | gephyrin | -0.00676042 |
| RPAP2 | RNA polymerase II associated protein 2 | -0.00675239 |
| RPAP3 | RNA polymerase II associated protein 3 | -0.00671192 |
| RPL34 | ribosomal protein L34 | -0.0067044 |
| RPS27A | ribosomal protein S27a | -0.0066944 |
