Cystathioninuria Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An elevated urinary concentration of cystathionine. (Human Phenotype Ontology, HP_0003153)
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Genes

57 genes co-occuring with the disease Cystathioninuria in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CTH cystathionine gamma-lyase 2.929
CBS cystathionine-beta-synthase 2.476
MPST mercaptopyruvate sulfurtransferase 2.104
ARMCX5 armadillo repeat containing, X-linked 5 2.073
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.873
NLE1 notchless homolog 1 (Drosophila) 1.746
ZNF460 zinc finger protein 460 1.742
TBCK TBC1 domain containing kinase 1.675
TST thiosulfate sulfurtransferase (rhodanese) 1.664
DGUOK deoxyguanosine kinase 1.647
SQOR sulfide quinone oxidoreductase 1.636
AMT aminomethyltransferase 1.573
GMPR guanosine monophosphate reductase 1.552
TRIM66 tripartite motif containing 66 1.488
GRSF1 G-rich RNA sequence binding factor 1 1.476
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 1.474
TMCO1 transmembrane and coiled-coil domains 1 1.449
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 1.447
MAT1A methionine adenosyltransferase I, alpha 1.44
SUOX sulfite oxidase 1.429
CCDC60 coiled-coil domain containing 60 1.404
RPIA ribose 5-phosphate isomerase A 1.387
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 1.381
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.374
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 1.325
ADSL adenylosuccinate lyase 1.32
ETHE1 ethylmalonic encephalopathy 1 1.318
CDO1 cysteine dioxygenase type 1 1.318
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 1.301
AS3MT arsenite methyltransferase 1.298
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 1.291
BIVM-ERCC5 BIVM-ERCC5 readthrough 1.29
OAT ornithine aminotransferase 1.288
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.287
ERCC5 excision repair cross-complementation group 5 1.266
MLYCD malonyl-CoA decarboxylase 1.265
GMPS guanine monphosphate synthase 1.252
GLDC glycine dehydrogenase (decarboxylating) 1.243
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 1.238
OPLAH 5-oxoprolinase (ATP-hydrolysing) 1.221
MEAK7 MTOR associated protein, eak-7 homolog 1.212
DAO D-amino-acid oxidase 1.198
TXN thioredoxin 1.149
CCNG2 cyclin G2 1.143
ATG3 autophagy related 3 1.139
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 1.139
CARS1 cysteinyl-tRNA synthetase 1 1.11
PTGR2 prostaglandin reductase 2 1.1
MSRB2 methionine sulfoxide reductase B2 1.097
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.083
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 1.083
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 1.053
NTHL1 nth endonuclease III-like 1 (E. coli) 1.043
SH2D1B SH2 domain containing 1B 1.039
KIF27 kinesin family member 27 1.03
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.027
MOCS3 molybdenum cofactor synthesis 3 1.012