| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.131297 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0983413 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0961578 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0885229 |
| NLGN1 | neuroligin 1 | 0.0852514 |
| ACTG1 | actin gamma 1 | 0.077293 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0704998 |
| YAP1 | Yes-associated protein 1 | 0.0674707 |
| PDGFC | platelet derived growth factor C | 0.0564358 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0557485 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0547677 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0513393 |
| TENM3 | teneurin transmembrane protein 3 | 0.0490289 |
| PCDH7 | protocadherin 7 | 0.0466681 |
| RPS12 | ribosomal protein S12 | 0.0455477 |
| RRM2 | ribonucleotide reductase M2 | 0.0452442 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0450161 |
| HDAC9 | histone deacetylase 9 | 0.0438587 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0435977 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0425224 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0421227 |
| INTS6 | integrator complex subunit 6 | 0.0419301 |
| POTEF | POTE ankyrin domain family, member F | 0.0395435 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0393697 |
| RPL37A | ribosomal protein L37a | 0.0390849 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.038104 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0368838 |
| RASAL2 | RAS protein activator like 2 | 0.0366526 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0358492 |
| BCHE | butyrylcholinesterase | 0.0351418 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0339862 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0339076 |
| RPS8 | ribosomal protein S8 | 0.0333286 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0332703 |
| AREG | amphiregulin | 0.0327463 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0312403 |
| WWOX | WW domain containing oxidoreductase | 0.0310458 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0307919 |
| TBCA | tubulin folding cofactor A | 0.0300203 |
| FTL | ferritin, light polypeptide | 0.0296042 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0287853 |
| RPS23 | ribosomal protein S23 | 0.0287296 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0285792 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0280127 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0265667 |
| BRD2 | bromodomain containing 2 | 0.0261934 |
| DENND5A | DENN/MADD domain containing 5A | 0.0259489 |
| SETD5 | SET domain containing 5 | 0.0256471 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0253104 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0251109 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0250039 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0245915 |
| EPHA6 | EPH receptor A6 | 0.0245651 |
| RCOR1 | REST corepressor 1 | 0.0244524 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0243918 |
| CMIP | c-Maf inducing protein | 0.0237347 |
| COMMD10 | COMM domain containing 10 | 0.0237037 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0236116 |
| PFN1 | profilin 1 | 0.0235243 |
| NEGR1 | neuronal growth regulator 1 | 0.023297 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0231104 |
| CCN2 | cellular communication network factor 2 | 0.023033 |
| NHSL1 | NHS-like 1 | 0.0228398 |
| PRKCE | protein kinase C, epsilon | 0.0227521 |
| RPS26 | ribosomal protein S26 | 0.0224518 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.022026 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218194 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0215105 |
| RBM19 | RNA binding motif protein 19 | 0.0215037 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0213793 |
| ADIPOR2 | adiponectin receptor 2 | 0.0212143 |
| AEBP2 | AE binding protein 2 | 0.0211902 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0209919 |
| RPL23 | ribosomal protein L23 | 0.0209162 |
| SERTAD2 | SERTA domain containing 2 | 0.0208935 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0208849 |
| PCDH9 | protocadherin 9 | 0.0207029 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0206254 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0206151 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0204451 |
| HELLS | helicase, lymphoid-specific | 0.020342 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0201316 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.020037 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0200252 |
| ASPH | aspartate beta-hydroxylase | 0.0199981 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0197774 |
| KIAA0232 | KIAA0232 | 0.0197146 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.0196982 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0196943 |
| ZNF644 | zinc finger protein 644 | 0.0195273 |
| MGAT4C | MGAT4 family, member C | 0.0194722 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0194213 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0193821 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193635 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0193201 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0192539 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0191593 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0191583 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.019065 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0189698 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.165024 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.078028 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0765535 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0666209 |
| PTMA | prothymosin, alpha | -0.0664819 |
| AHNAK | AHNAK nucleoprotein | -0.0659321 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0520878 |
| ANXA1 | annexin A1 | -0.0514311 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0513557 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0481938 |
| TPI1 | triosephosphate isomerase 1 | -0.0481237 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0474841 |
| EHBP1 | EH domain binding protein 1 | -0.0457638 |
| TMEM123 | transmembrane protein 123 | -0.0454221 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0453712 |
| MKI67 | marker of proliferation Ki-67 | -0.0443517 |
| TMEM41B | transmembrane protein 41B | -0.0441598 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0426689 |
| PEG10 | paternally expressed 10 | -0.0413678 |
| TXNRD1 | thioredoxin reductase 1 | -0.0411202 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0399091 |
| KIF5B | kinesin family member 5B | -0.0387836 |
| VMP1 | vacuole membrane protein 1 | -0.0385364 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0385003 |
| PGK1 | phosphoglycerate kinase 1 | -0.0375495 |
| XPO1 | exportin 1 | -0.0368336 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0344317 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0336549 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0334781 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0325871 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0324225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0313351 |
| H1-0 | H1.0 linker histone | -0.0312058 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0309455 |
| CAVIN1 | caveolae associated protein 1 | -0.0307086 |
| CLDN1 | claudin 1 | -0.0306629 |
| LMO7 | LIM domain 7 | -0.0291155 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0288316 |
| ZNF217 | zinc finger protein 217 | -0.0288114 |
| S100A6 | S100 calcium binding protein A6 | -0.0285101 |
| JMJD1C | jumonji domain containing 1C | -0.0270408 |
| MATR3 | matrin 3 | -0.0268833 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0265484 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0264114 |
| FAM162A | family with sequence similarity 162, member A | -0.0261872 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0260095 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0259914 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0259134 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0257563 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0249534 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0246174 |
| NF1 | neurofibromin 1 | -0.0245762 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0244964 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.023916 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0238073 |
| ECT2 | epithelial cell transforming 2 | -0.0236587 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0234339 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0231736 |
| PRKCI | protein kinase C, iota | -0.0230785 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0229914 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226168 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0225227 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0225018 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0223469 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0221021 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0220568 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0218962 |
| KLF6 | Kruppel-like factor 6 | -0.0217137 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0216661 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0213676 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0213248 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0208549 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0207771 |
| MAP1B | microtubule-associated protein 1B | -0.0207177 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0203266 |
| PREPL | prolyl endopeptidase-like | -0.020321 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0202113 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0198762 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0197897 |
| SEPTIN7 | septin 7 | -0.019271 |
| MMP12 | matrix metallopeptidase 12 | -0.0192548 |
| TCERG1 | transcription elongation regulator 1 | -0.0192512 |
| SPAG9 | sperm associated antigen 9 | -0.0192392 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0192231 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.0191569 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0190962 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.018889 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.018831 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0187665 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0186087 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0185776 |
| ENO1 | enolase 1, (alpha) | -0.0185754 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.0183201 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0182068 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0181958 |
| TUT4 | terminal uridylyl transferase 4 | -0.0181286 |
| FBXO11 | F-box protein 11 | -0.0180583 |
| NEK7 | NIMA-related kinase 7 | -0.017963 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0177851 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0176758 |
