| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Cysteamine (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.123609 |
| HLA-B | major histocompatibility complex, class I, B | 0.123008 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.118299 |
| APOL1 | apolipoprotein L, 1 | 0.0872492 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0767764 |
| CALU | calumenin | 0.0754851 |
| APP | amyloid beta (A4) precursor protein | 0.0745482 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0712792 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0685888 |
| RPS2 | ribosomal protein S2 | 0.0638769 |
| CA12 | carbonic anhydrase XII | 0.0552726 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.054188 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0540076 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0535127 |
| CAVIN1 | caveolae associated protein 1 | 0.0506065 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0503533 |
| NDRG1 | N-myc downstream regulated 1 | 0.0476847 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0476158 |
| RPL37A | ribosomal protein L37a | 0.045568 |
| SFTPA2 | surfactant protein A2 | 0.045374 |
| RPL26 | ribosomal protein L26 | 0.0439608 |
| SEPTIN9 | septin 9 | 0.0436945 |
| NAV2 | neuron navigator 2 | 0.0436486 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0429271 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0423782 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0417954 |
| PLEC | plectin | 0.0415004 |
| ANKRD11 | ankyrin repeat domain 11 | 0.040748 |
| RND3 | Rho family GTPase 3 | 0.0395587 |
| CD44 | CD44 molecule (Indian blood group) | 0.0395474 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0372632 |
| RPS6 | ribosomal protein S6 | 0.0371279 |
| CP | ceruloplasmin (ferroxidase) | 0.0367222 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0358778 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0358359 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0351756 |
| GPC5 | glypican 5 | 0.0350384 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0349037 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0347831 |
| RPL28 | ribosomal protein L28 | 0.0335206 |
| COL5A1 | collagen, type V, alpha 1 | 0.033212 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0329707 |
| RPL37 | ribosomal protein L37 | 0.0326198 |
| VEGFA | vascular endothelial growth factor A | 0.0324768 |
| FSTL1 | follistatin-like 1 | 0.0324767 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0310716 |
| CTSD | cathepsin D | 0.0308501 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0307821 |
| GOLGB1 | golgin B1 | 0.0305892 |
| LOXL2 | lysyl oxidase-like 2 | 0.030415 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0304145 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0303538 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0298641 |
| TLN1 | talin 1 | 0.0298314 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 0.0296807 |
| RRBP1 | ribosome binding protein 1 | 0.0294823 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0287024 |
| RPL27 | ribosomal protein L27 | 0.0286781 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.02851 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0283251 |
| HLA-A | major histocompatibility complex, class I, A | 0.0281171 |
| FAM13A | family with sequence similarity 13, member A | 0.0280389 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0279606 |
| LMNA | lamin A/C | 0.0278893 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0277882 |
| ATP13A3 | ATPase type 13A3 | 0.0274451 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0272865 |
| UBE3C | ubiquitin protein ligase E3C | 0.0272699 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0268616 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0266875 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0266028 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0264758 |
| HDLBP | high density lipoprotein binding protein | 0.0264354 |
| PRKCA | protein kinase C, alpha | 0.0262266 |
| SET | SET nuclear proto-oncogene | 0.0261658 |
| RPS8 | ribosomal protein S8 | 0.0256251 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.025599 |
| MYO1E | myosin IE | 0.0254677 |
| HLA-C | major histocompatibility complex, class I, C | 0.0252978 |
| ACTG1 | actin gamma 1 | 0.024961 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0249494 |
| CD82 | CD82 molecule | 0.0247259 |
| OSMR | oncostatin M receptor | 0.0246168 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0245945 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0245699 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0244006 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0243024 |
| SDC4 | syndecan 4 | 0.0242796 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0242787 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0242188 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0241788 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0241336 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0239852 |
| EFNA5 | ephrin-A5 | 0.0238529 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0238104 |
| FAM107B | family with sequence similarity 107, member B | 0.0237905 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0236612 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0236437 |
| SURF4 | surfeit 4 | 0.0236241 |
| HLA-E | major histocompatibility complex, class I, E | 0.0233845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.183299 |
| FTL | ferritin, light polypeptide | -0.178042 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.135235 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.112469 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.100865 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0967219 |
| TMSB10 | thymosin beta 10 | -0.0894615 |
| TXNRD1 | thioredoxin reductase 1 | -0.0805908 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0594727 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.05773 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.05767 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0560854 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0548803 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0540908 |
| PKM | pyruvate kinase, muscle | -0.0536757 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0506727 |
| PFN1 | profilin 1 | -0.0504162 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0498703 |
| PLK2 | polo-like kinase 2 | -0.0453648 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0450671 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0449462 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.044211 |
| ANLN | anillin, actin binding protein | -0.0429924 |
| CADM1 | cell adhesion molecule 1 | -0.0429544 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0427691 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0423739 |
| NRP2 | neuropilin 2 | -0.0420199 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0417454 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0414794 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0406303 |
| TUBA1B | tubulin, alpha 1b | -0.0360192 |
| CENPF | centromere protein F, 350/400kDa | -0.0351655 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0348979 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.03479 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.034392 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0336665 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0327942 |
| CCNL1 | cyclin L1 | -0.0326225 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0321643 |
| RHEB | Ras homolog enriched in brain | -0.0315884 |
| G0S2 | G0/G1 switch 2 | -0.0306827 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0304328 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0302784 |
| RTN4 | reticulon 4 | -0.0298001 |
| RPS5 | ribosomal protein S5 | -0.0297688 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0294739 |
| RPL35A | ribosomal protein L35a | -0.0292077 |
| ANKRD33B | ankyrin repeat domain 33B | -0.028936 |
| TFG | TRK-fused gene | -0.0289092 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.028828 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0286506 |
| CXXC1 | CXXC finger protein 1 | -0.0285189 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0283676 |
| PCBP2 | poly(rC) binding protein 2 | -0.0282192 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0279864 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0277905 |
| INSIG1 | insulin induced gene 1 | -0.0277878 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0275198 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0273969 |
| MORF4L2 | mortality factor 4 like 2 | -0.0273641 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0270243 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0269112 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0265467 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0263909 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0261459 |
| MAP1B | microtubule-associated protein 1B | -0.0259825 |
| VCAN | versican | -0.0259758 |
| CLTC | clathrin, heavy chain (Hc) | -0.0257701 |
| ITGAV | integrin, alpha V | -0.0255927 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0255262 |
| S100A10 | S100 calcium binding protein A10 | -0.0253713 |
| CLINT1 | clathrin interactor 1 | -0.02536 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0252358 |
| PLPP3 | phospholipid phosphatase 3 | -0.0251766 |
| SEPTIN7 | septin 7 | -0.0247186 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0243394 |
| IRF1 | interferon regulatory factor 1 | -0.0243302 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0242921 |
| CD70 | CD70 molecule | -0.0242521 |
| RNF145 | ring finger protein 145 | -0.0242246 |
| DIAPH3 | diaphanous-related formin 3 | -0.0239916 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0234121 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0233726 |
| CDK6 | cyclin-dependent kinase 6 | -0.0233418 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0232588 |
| NFIB | nuclear factor I/B | -0.0232443 |
| CBX3 | chromobox homolog 3 | -0.0232216 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0232164 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0231011 |
| SPAG9 | sperm associated antigen 9 | -0.0230128 |
| GLIS3 | GLIS family zinc finger 3 | -0.022959 |
| SDCBP | syndecan binding protein (syntenin) | -0.0227324 |
| TKT | transketolase | -0.0227148 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0226501 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.0226057 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0225954 |
| TAGLN2 | transgelin 2 | -0.0225435 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0224865 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0224791 |
| MTF2 | metal response element binding transcription factor 2 | -0.022312 |
