| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.22985 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.206074 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0816494 |
| PDE10A | phosphodiesterase 10A | 0.0695078 |
| FNIP1 | folliculin interacting protein 1 | 0.0618636 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0616847 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0556929 |
| GSE1 | Gse1 coiled-coil protein | 0.049011 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0483124 |
| SMYD3 | SET and MYND domain containing 3 | 0.0483028 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0460058 |
| PCM1 | pericentriolar material 1 | 0.045642 |
| BBX | bobby sox homolog (Drosophila) | 0.0444799 |
| VEGFA | vascular endothelial growth factor A | 0.0433704 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0414289 |
| KIF1B | kinesin family member 1B | 0.0401133 |
| CUX1 | cut-like homeobox 1 | 0.0395503 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0389339 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0388298 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.038248 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0381282 |
| PRELID2 | PRELI domain containing 2 | 0.0364277 |
| SIK3 | SIK family kinase 3 | 0.0360912 |
| EGFR | epidermal growth factor receptor | 0.0359149 |
| TNS3 | tensin 3 | 0.0358029 |
| HMGA2 | high mobility group AT-hook 2 | 0.0356424 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0355441 |
| PTEN | phosphatase and tensin homolog | 0.0349585 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0345178 |
| SPIDR | scaffolding protein involved in DNA repair | 0.033997 |
| RANBP17 | RAN binding protein 17 | 0.0338547 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0338293 |
| ACTG1 | actin gamma 1 | 0.0337898 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0333685 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0329962 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0326951 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0319447 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0317384 |
| ITGAV | integrin, alpha V | 0.0314362 |
| HDAC8 | histone deacetylase 8 | 0.0306597 |
| WWOX | WW domain containing oxidoreductase | 0.0306367 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.030407 |
| HELLS | helicase, lymphoid-specific | 0.0302837 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0301216 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0300207 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0299146 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0296489 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0294532 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0293277 |
| RPS2 | ribosomal protein S2 | 0.0291209 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0289316 |
| NBEA | neurobeachin | 0.0285126 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0284204 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0282993 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0280578 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0279538 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0277673 |
| UST | uronyl-2-sulfotransferase | 0.0276648 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0269967 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0269226 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0267515 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0265532 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0264836 |
| TXNRD1 | thioredoxin reductase 1 | 0.0262671 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0261794 |
| RPL37 | ribosomal protein L37 | 0.0261473 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0259482 |
| GANAB | glucosidase, alpha; neutral AB | 0.0258649 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0258568 |
| SMC1A | structural maintenance of chromosomes 1A | 0.025732 |
| DIAPH3 | diaphanous-related formin 3 | 0.0255676 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0251223 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0249414 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0247799 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0247531 |
| PDE8A | phosphodiesterase 8A | 0.0242504 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.024025 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0239661 |
| RPL3 | ribosomal protein L3 | 0.02385 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0237248 |
| FRMD6 | FERM domain containing 6 | 0.0236465 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.0232357 |
| SCGB1D1 | secretoglobin, family 1D, member 1 | 0.0230005 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0228779 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0228416 |
| UBE3A | ubiquitin protein ligase E3A | 0.0226056 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.0225579 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.0218853 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0217644 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0216386 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0215139 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0214443 |
| TRIM44 | tripartite motif containing 44 | 0.0213958 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0212321 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0211478 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0211295 |
| HOXA3 | homeobox A3 | 0.0210263 |
| ATXN2L | ataxin 2-like | 0.0209485 |
| MTREX | Mtr4 exosome RNA helicase | 0.0208348 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0208103 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102453 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0752155 |
| PEG10 | paternally expressed 10 | -0.0733139 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0729655 |
| FTL | ferritin, light polypeptide | -0.0638925 |
| TMSB10 | thymosin beta 10 | -0.0575527 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0563882 |
| PTMA | prothymosin, alpha | -0.0507257 |
| PHF3 | PHD finger protein 3 | -0.0489486 |
| MATR3 | matrin 3 | -0.0484591 |
| CANX | calnexin | -0.0466051 |
| QKI | QKI, KH domain containing, RNA binding | -0.0435626 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0431162 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0420156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0418091 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0405978 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0396165 |
| MT2A | metallothionein 2A | -0.039469 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0392288 |
| ZNF292 | zinc finger protein 292 | -0.0386203 |
| TFRC | transferrin receptor | -0.0385638 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0368909 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.036185 |
| HBP1 | HMG-box transcription factor 1 | -0.035807 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0356679 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.035446 |
| GNAS | GNAS complex locus | -0.035285 |
| RPL35A | ribosomal protein L35a | -0.034655 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0346536 |
| YBX1 | Y box binding protein 1 | -0.0341787 |
| CDC73 | cell division cycle 73 | -0.0334367 |
| ZNF207 | zinc finger protein 207 | -0.0331085 |
| IGF2 | insulin-like growth factor 2 | -0.0329753 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0320714 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0320328 |
| SPAG9 | sperm associated antigen 9 | -0.0315037 |
| RPS24 | ribosomal protein S24 | -0.0314984 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0314728 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0313379 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0311939 |
| RPS25 | ribosomal protein S25 | -0.0311739 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0311333 |
| MTDH | metadherin | -0.0305035 |
| PGK1 | phosphoglycerate kinase 1 | -0.030489 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0303886 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301886 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0299218 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0298635 |
| CADM2 | cell adhesion molecule 2 | -0.0297564 |
| NDRG1 | N-myc downstream regulated 1 | -0.029671 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0295441 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0295264 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0294075 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0292329 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0291326 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0290399 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.029032 |
| RPL5 | ribosomal protein L5 | -0.0289034 |
| RPL19 | ribosomal protein L19 | -0.0288209 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0283556 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0281319 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0278918 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0276258 |
| GOLGA4 | golgin A4 | -0.0273472 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | -0.0271863 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0270981 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0270472 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0269364 |
| NOP58 | NOP58 ribonucleoprotein | -0.026907 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0267564 |
| MAP4 | microtubule-associated protein 4 | -0.0265781 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.026398 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0263599 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0262639 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.026198 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0260607 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0260587 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0260134 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0259871 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.025819 |
| RHEB | Ras homolog enriched in brain | -0.0258085 |
| RPL8 | ribosomal protein L8 | -0.0257217 |
| RFX7 | regulatory factor X, 7 | -0.0254377 |
| CERT1 | ceramide transporter 1 | -0.025319 |
| CBFB | core-binding factor, beta subunit | -0.0252691 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0252035 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0250672 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.02484 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0245493 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0245334 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0244441 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244141 |
| IER3 | immediate early response 3 | -0.0241208 |
| USP24 | ubiquitin specific peptidase 24 | -0.0240636 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0240376 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0239409 |
| TULP4 | tubby like protein 4 | -0.0239296 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0238881 |
| USP3 | ubiquitin specific peptidase 3 | -0.023852 |
