| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.13443 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.128604 |
| VMP1 | vacuole membrane protein 1 | 0.121466 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.101544 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0869718 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0868408 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0751487 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0746882 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0691214 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0687452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0662057 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0618993 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0616376 |
| DUSP16 | dual specificity phosphatase 16 | 0.0597259 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0576143 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0574989 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0556155 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0551578 |
| OSMR | oncostatin M receptor | 0.0546391 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0540711 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0516812 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0515232 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.050587 |
| EXT1 | exostosin glycosyltransferase 1 | 0.050307 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0502927 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0500959 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.0497157 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0490146 |
| MYO1B | myosin IB | 0.0478181 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0475947 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0464443 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0449982 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 0.044017 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0436706 |
| INSR | insulin receptor | 0.0434915 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0429509 |
| SMYD3 | SET and MYND domain containing 3 | 0.0429438 |
| NTN4 | netrin 4 | 0.0423963 |
| APP | amyloid beta (A4) precursor protein | 0.0423815 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0422437 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0420717 |
| SET | SET nuclear proto-oncogene | 0.0411174 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0399722 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0394403 |
| TMEM165 | transmembrane protein 165 | 0.03881 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0379795 |
| YAP1 | Yes-associated protein 1 | 0.0379414 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0378647 |
| ATXN1 | ataxin 1 | 0.0372487 |
| POTEF | POTE ankyrin domain family, member F | 0.0367589 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0365395 |
| AHR | aryl hydrocarbon receptor | 0.0363843 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.036158 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0361379 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0361379 |
| ASPH | aspartate beta-hydroxylase | 0.0360559 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0352009 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0351121 |
| ADNP | activity-dependent neuroprotector homeobox | 0.034882 |
| GLCCI1 | glucocorticoid induced 1 | 0.0345502 |
| SMAD3 | SMAD family member 3 | 0.0343088 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0342028 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0337956 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.03317 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0331192 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0324343 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0323568 |
| S100A8 | S100 calcium binding protein A8 | 0.0321689 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.032033 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0313619 |
| SYTL2 | synaptotagmin-like 2 | 0.0313403 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.0312476 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0309641 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0304079 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0304014 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0303183 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0302433 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0301142 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0300008 |
| S100A9 | S100 calcium binding protein A9 | 0.0295924 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0294454 |
| ANXA2 | annexin A2 | 0.0290927 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0289462 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0289179 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0288699 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0285478 |
| AREG | amphiregulin | 0.0284928 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0283122 |
| MYOF | myoferlin | 0.0281564 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0277762 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0277562 |
| LMO7 | LIM domain 7 | 0.0277353 |
| USP53 | ubiquitin specific peptidase 53 | 0.0276555 |
| EGFR | epidermal growth factor receptor | 0.0273984 |
| SGMS1 | sphingomyelin synthase 1 | 0.0271929 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.02713 |
| BDKRB2 | bradykinin receptor B2 | 0.0269397 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0266975 |
| TC2N | tandem C2 domains, nuclear | 0.0266676 |
| STOM | stomatin | 0.0262311 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.175997 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121165 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.106266 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0711877 |
| PTMA | prothymosin, alpha | -0.0649513 |
| RPL19 | ribosomal protein L19 | -0.0542483 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0519038 |
| INTS6 | integrator complex subunit 6 | -0.0506509 |
| CDK12 | cyclin-dependent kinase 12 | -0.0496051 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0493373 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0486417 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0475745 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0462857 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0457943 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0426858 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.042656 |
| CLTC | clathrin, heavy chain (Hc) | -0.0422341 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406371 |
| LASP1 | LIM and SH3 protein 1 | -0.0403779 |
| CEP250 | centrosomal protein 250kDa | -0.0388644 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.038426 |
| TMSB4X | thymosin beta 4, X-linked | -0.0383801 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0383043 |
| RPS24 | ribosomal protein S24 | -0.0372733 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0366307 |
| TMEM123 | transmembrane protein 123 | -0.0364754 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0357311 |
| RRBP1 | ribosome binding protein 1 | -0.0355901 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0352112 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0351164 |
| DENND1A | DENN/MADD domain containing 1A | -0.0346005 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0345765 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0322914 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0322683 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0317855 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0305105 |
| RPL37A | ribosomal protein L37a | -0.03004 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | -0.0299791 |
| CANX | calnexin | -0.0289799 |
| AEBP2 | AE binding protein 2 | -0.0285538 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0284977 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0278097 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0275909 |
| TFRC | transferrin receptor | -0.0271256 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0270605 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0269701 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0269206 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0267996 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0263749 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0261093 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.0260115 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0258785 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0253633 |
| PLSCR2 | phospholipid scramblase 2 | -0.0247558 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0238377 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0235359 |
| UBAP2 | ubiquitin associated protein 2 | -0.0235001 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0232388 |
| KIF16B | kinesin family member 16B | -0.0231762 |
| MYL12B | myosin, light chain 12B, regulatory | -0.022759 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.022732 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226455 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0223718 |
| SCFD1 | sec1 family domain containing 1 | -0.0222969 |
| ARF1 | ADP-ribosylation factor 1 | -0.0221626 |
| RPS3 | ribosomal protein S3 | -0.0218874 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0218653 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0216862 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0208841 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0208754 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0208248 |
| TENM2 | teneurin transmembrane protein 2 | -0.0205927 |
| RPL34 | ribosomal protein L34 | -0.0203281 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0201132 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.020105 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0200299 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | -0.0200093 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0198999 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0197814 |
| ANLN | anillin, actin binding protein | -0.019777 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0196655 |
| SBF2 | SET binding factor 2 | -0.0196558 |
| NRF1 | nuclear respiratory factor 1 | -0.0195626 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0193294 |
| FBXO34 | F-box protein 34 | -0.0191475 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0191305 |
| RPL12 | ribosomal protein L12 | -0.0191176 |
| STIP1 | stress-induced phosphoprotein 1 | -0.0190737 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0190567 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0190256 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0190093 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0189673 |
| ACSF2 | acyl-CoA synthetase family member 2 | -0.0189068 |
| VCP | valosin containing protein | -0.0188898 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0188631 |
| ECT2 | epithelial cell transforming 2 | -0.0185897 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0185504 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0184219 |
| RPL31 | ribosomal protein L31 | -0.0183507 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0182503 |
