| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Cysteamine (hydrochloride) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Cysteamine (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.166752 |
| ZNF608 | zinc finger protein 608 | 0.108904 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.108858 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.108593 |
| JMJD1C | jumonji domain containing 1C | 0.0919549 |
| RAD51B | RAD51 paralog B | 0.0890164 |
| SHROOM3 | shroom family member 3 | 0.0759556 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0754947 |
| TOX | thymocyte selection-associated high mobility group box | 0.0741602 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0692623 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0672763 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0668428 |
| VCL | vinculin | 0.0647685 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0644625 |
| ZNF638 | zinc finger protein 638 | 0.0644059 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0607377 |
| CABIN1 | calcineurin binding protein 1 | 0.0581013 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0566929 |
| CCDC88A | coiled-coil domain containing 88A | 0.0562294 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0552348 |
| ZNF644 | zinc finger protein 644 | 0.0551136 |
| VMP1 | vacuole membrane protein 1 | 0.0507926 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0501595 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0493452 |
| BNC2 | basonuclin 2 | 0.0485971 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0471398 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0465502 |
| PCM1 | pericentriolar material 1 | 0.0461886 |
| HOMER1 | homer scaffolding protein 1 | 0.0449781 |
| HSPA8 | heat shock 70kDa protein 8 | 0.044906 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0446771 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0444371 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0439501 |
| PCBP2 | poly(rC) binding protein 2 | 0.0435073 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0420551 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0409791 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0406411 |
| MLIP | muscular LMNA-interacting protein | 0.0405716 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0397486 |
| HELLS | helicase, lymphoid-specific | 0.0393408 |
| MEMO1 | mediator of cell motility 1 | 0.0392766 |
| PDE7A | phosphodiesterase 7A | 0.0390488 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0386925 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.038245 |
| SERTAD2 | SERTA domain containing 2 | 0.0381723 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0381445 |
| NUP58 | nucleoporin 58 | 0.0380956 |
| DST | dystonin | 0.0377702 |
| RPL3 | ribosomal protein L3 | 0.0376968 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0372226 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0369889 |
| WLS | wntless Wnt ligand secretion mediator | 0.0367839 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0366163 |
| PDE8A | phosphodiesterase 8A | 0.0363743 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0357389 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0353519 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0350915 |
| AUTS2 | autism susceptibility candidate 2 | 0.0349403 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0342627 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0340601 |
| MED13 | mediator complex subunit 13 | 0.0340037 |
| CDC73 | cell division cycle 73 | 0.033922 |
| APP | amyloid beta (A4) precursor protein | 0.0338583 |
| CDH18 | cadherin 18, type 2 | 0.0337938 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0337873 |
| H1-0 | H1.0 linker histone | 0.0336845 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0336738 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0331849 |
| RCOR1 | REST corepressor 1 | 0.0330591 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0323466 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0322744 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0322693 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0321924 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.031929 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0319178 |
| SETD5 | SET domain containing 5 | 0.0318158 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0318053 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0312695 |
| JUN | jun proto-oncogene | 0.0310344 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.031031 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0309834 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0307709 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.030705 |
| OGA | O-GlcNAcase | 0.0306303 |
| EGR1 | early growth response 1 | 0.0305693 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0305614 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0304444 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0303627 |
| ZNF292 | zinc finger protein 292 | 0.0302525 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0302482 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.030106 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0300394 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0300301 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0299887 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0298994 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0298867 |
| MCL1 | myeloid cell leukemia 1 | 0.0294415 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0294355 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0293611 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0289906 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPAS3 | neuronal PAS domain protein 3 | -0.0879368 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0856937 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0856248 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0781565 |
| RPS24 | ribosomal protein S24 | -0.0555866 |
| PTMA | prothymosin, alpha | -0.0515755 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.046784 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0455982 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.041765 |
| RPLP1 | ribosomal protein, large, P1 | -0.041554 |
| RPS8 | ribosomal protein S8 | -0.0410294 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0408692 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0393163 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0391844 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0384918 |
| TMSB10 | thymosin beta 10 | -0.0375392 |
| RPL4 | ribosomal protein L4 | -0.0369694 |
| CANX | calnexin | -0.0361071 |
| RPS5 | ribosomal protein S5 | -0.0357515 |
| ZNF33A | zinc finger protein 33A | -0.0350667 |
| RPS19 | ribosomal protein S19 | -0.0327507 |
| ZNF217 | zinc finger protein 217 | -0.0323889 |
| RPLP0 | ribosomal protein, large, P0 | -0.0322857 |
| RPL34 | ribosomal protein L34 | -0.0313648 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0313495 |
| RACK1 | receptor for activated C kinase 1 | -0.0312164 |
| RPS13 | ribosomal protein S13 | -0.0306205 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0299655 |
| RPL31 | ribosomal protein L31 | -0.0289892 |
| RPL12 | ribosomal protein L12 | -0.0284249 |
| RPL37A | ribosomal protein L37a | -0.0283335 |
| VIM | vimentin | -0.0280635 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0279454 |
| LDHA | lactate dehydrogenase A | -0.027766 |
| RPS27A | ribosomal protein S27a | -0.0274671 |
| RPL6 | ribosomal protein L6 | -0.0265463 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0261519 |
| EMP1 | epithelial membrane protein 1 | -0.0259869 |
| RPS28 | ribosomal protein S28 | -0.0256952 |
| RPL7 | ribosomal protein L7 | -0.0251991 |
| MAP4 | microtubule-associated protein 4 | -0.024838 |
| TENM3 | teneurin transmembrane protein 3 | -0.0248205 |
| CENPF | centromere protein F, 350/400kDa | -0.0247311 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0247033 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0243242 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0240606 |
| SNRPD3 | small nuclear ribonucleoprotein D3 polypeptide 18kDa | -0.0237 |
| RPS23 | ribosomal protein S23 | -0.0235816 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.023313 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0231741 |
| RPL38 | ribosomal protein L38 | -0.022546 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0222886 |
| RPL36A | ribosomal protein L36a | -0.0222379 |
| TMEM14B | transmembrane protein 14B | -0.0219111 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0219051 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0217872 |
| ZNF770 | zinc finger protein 770 | -0.0213429 |
| RPL35A | ribosomal protein L35a | -0.0210027 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.0207337 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0205878 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0205481 |
| NGLY1 | N-glycanase 1 | -0.02046 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0203984 |
| RPLP2 | ribosomal protein, large, P2 | -0.0202349 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.0201209 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0200792 |
| ZFP64 | ZFP64 zinc finger protein | -0.0197495 |
| XPOT | exportin, tRNA | -0.0196688 |
| SRP72 | signal recognition particle 72kDa | -0.0194266 |
| RPS25 | ribosomal protein S25 | -0.0193015 |
| HSPA4 | heat shock 70kDa protein 4 | -0.0192437 |
| KIAA1958 | KIAA1958 | -0.0191446 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0190972 |
| SSR1 | signal sequence receptor, alpha | -0.0188782 |
| HMGB1 | high mobility group box 1 | -0.0188283 |
| ARF1 | ADP-ribosylation factor 1 | -0.0186472 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0185669 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0183748 |
| RPS6 | ribosomal protein S6 | -0.0182672 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.018121 |
| RPS4X | ribosomal protein S4, X-linked | -0.017995 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0178864 |
| TUBA1B | tubulin, alpha 1b | -0.0178592 |
| ZFR | zinc finger RNA binding protein | -0.017821 |
| RPL10A | ribosomal protein L10a | -0.0176317 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0175285 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0174819 |
| RAN | RAN, member RAS oncogene family | -0.0173895 |
| RPL7A | ribosomal protein L7a | -0.0173557 |
| CDV3 | CDV3 homolog (mouse) | -0.0173388 |
| HHIP | hedgehog interacting protein | -0.0173211 |
| RPL32 | ribosomal protein L32 | -0.0172707 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0171174 |
| PREPL | prolyl endopeptidase-like | -0.017076 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | -0.0170481 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.016901 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0167895 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0167144 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0166987 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0166841 |
